Stoke Therapeutics (STOK) Operating Margin (2022 - 2026)
Stoke Therapeutics' quarterly Operating Margin came in at 857.57% in Q1 2026, down 92772.0% year-on-year from N/an in Q1 2025, and up 80.43% quarter-over-quarter from 4382.24% in Q4 2025.
Stoke Therapeutics has reported Operating Margin for 5 years, with the latest figure at 857.57% in Q1 2026.
- For the quarter ending Q1 2026, Operating Margin fell 92772.0% year-over-year to 857.57%; the trailing twelve-month figure through Mar 2026 stood at 577.46% (down 59749.0% YoY), and the FY2025 full-year result was 11.16%, up 26615.0% from the prior year.
- Operating Margin for Q1 2026 stood at 857.57%, up from 4382.24% in the prior quarter.
- The five-year high for Operating Margin was 70.15% in Q1 2025, with the low at 4382.24% in Q4 2025.
- Average Operating Margin over 5 years is 870.53%, with a median of 781.12% recorded in 2022.
- Year-over-year, Operating Margin surged 99551 bps in 2024 and sank 432187 bps in 2025.
- Tracing STOK's Operating Margin over 5 years: stood at 831.58% in 2022, then fell by 27 bps to 1055.89% in 2023, then soared by 94 bps to 60.37% in 2024, then plunged by 7158 bps to 4382.24% in 2025, then surged by 80 bps to 857.57% in 2026.
- The last three Operating Margin figures came in at 857.57% (Q1 2026), 4382.24% (Q4 2025), and 405.3% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 17.83% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 23.02% |
| 10 | Stoke Therapeutics | 1.92 Bn | 1.92 Bn | - | -857.57% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -857.57% |
| Dec 31, 2025 | -4,382.24% |
| Sep 30, 2025 | -405.30% |
| Jun 30, 2025 | -197.58% |
| Mar 31, 2025 | 70.15% |
| Dec 31, 2024 | -60.37% |
| Sep 30, 2024 | -613.06% |
| Jun 30, 2024 | -607.37% |
| Mar 31, 2024 | -672.96% |
| Dec 31, 2023 | -1,055.89% |
| Sep 30, 2023 | -823.28% |
| Jun 30, 2023 | -1,340.67% |
| Mar 31, 2023 | -479.23% |
| Dec 31, 2022 | -831.58% |
| Sep 30, 2022 | -934.53% |
| Jun 30, 2022 | -781.12% |
| Mar 31, 2022 | -826.50% |