Stoke Therapeutics (STOK) EBITDA (2018 - 2026)

Stoke Therapeutics' quarterly EBITDA came in at -$50.7 million in Q1 2026, down 144.86% year-on-year from $112.9 million in Q1 2025, and up 12.41% quarter-over-quarter from -$57.8 million in Q4 2025.

Stoke Therapeutics has reported EBITDA for 9 years, with the latest figure at -$50.7 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 144.86% year-over-year to -$50.7 million; the trailing twelve-month figure through Mar 2026 stood at -$169.8 million (down 438.42% YoY), and the FY2025 full-year result was -$6.2 million, up 93.05% from the prior year.
  • EBITDA for Q1 2026 stood at -$50.7 million, up from -$57.8 million in the prior quarter.
  • The five-year high for EBITDA was $112.9 million in Q1 2025, with the low at -$57.8 million in Q4 2025.
  • Average EBITDA over 5 years is -$20.7 million, with a median of -$25.7 million recorded in 2024.
  • Peak annual rise in EBITDA reached 528.56% in 2025, while the deepest fall reached 435.58% in 2025.
  • Tracing STOK's EBITDA over 5 years: stood at -$25.1 million in 2022, then fell by 6.8% to -$26.8 million in 2023, then jumped by 59.76% to -$10.8 million in 2024, then sank by 435.58% to -$57.8 million in 2025, then advanced by 12.41% to -$50.7 million in 2026.
  • The last three EBITDA figures came in at -$50.7 million (Q1 2026), -$57.8 million (Q4 2025), and -$38.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -13.63 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 201.19 Mn
10 Stoke Therapeutics 1.92 Bn 1.92 Bn - -50.66 Mn

Historic Data

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DateValue
Mar 31, 2026 -50.66 Mn
Dec 31, 2025 -57.84 Mn
Sep 30, 2025 -38.00 Mn
Jun 30, 2025 -23.28 Mn
Mar 31, 2025 112.93 Mn
Dec 31, 2024 -10.80 Mn
Sep 30, 2024 -26.25 Mn
Jun 30, 2024 -25.71 Mn
Mar 31, 2024 -26.35 Mn
Dec 31, 2023 -26.84 Mn
Sep 30, 2023 -24.31 Mn
Jun 30, 2023 -30.44 Mn
Mar 31, 2023 -21.97 Mn
Dec 31, 2022 -25.13 Mn
Sep 30, 2022 -26.54 Mn
Jun 30, 2022 -25.24 Mn
Mar 31, 2022 -25.17 Mn
Dec 31, 2021 -24.59 Mn
Sep 30, 2021 -22.58 Mn
Jun 30, 2021 -22.01 Mn
Mar 31, 2021 -16.79 Mn
Dec 31, 2020 -14.56 Mn
Sep 30, 2020 -13.68 Mn
Jun 30, 2020 -12.96 Mn
Mar 31, 2020 -11.74 Mn
Dec 31, 2019 -11.07 Mn
Sep 30, 2019 -9.84 Mn
Jun 30, 2019 -8.45 Mn
Mar 31, 2019 -6.32 Mn
Dec 31, 2018 -4.54 Mn
Sep 30, 2018 -3.32 Mn
Jun 30, 2018 -3.01 Mn