Stoke Therapeutics (STOK) EBITDA (2018 - 2026)

Stoke Therapeutics (STOK) recorded quarterly EBITDA of -$50.7 million in Q1 2026, up 12.41% quarter-over-quarter from -$57.8 million in Q4 2025, and down 144.86% on a YoY basis from $112.9 million in Q1 2025.

Stoke Therapeutics (STOK) EBITDA (2018 - 2026) Analysis & Trends

Stoke Therapeutics' EBITDA history runs 9 years deep, the most recent figure standing at -$50.7 million for Q1 2026.

  • In Q1 2026, EBITDA fell 144.86% year-over-year to -$50.7 million; the TTM figure through Mar 2026 stood at -$169.8 million (down 438.42% YoY), while the FY2025 annual figure was -$6.2 million, up 93.05% from the prior year.
  • EBITDA was -$50.7 million for Q1 2026 at Stoke Therapeutics, up from -$57.8 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $112.9 million in Q1 2025 to a low of -$57.8 million in Q4 2025.
  • Historically, EBITDA has averaged -$20.7 million across 5 years, with a median of -$25.7 million in 2024.
  • Biggest YoY gain for EBITDA was 528.56% in 2025; the steepest drop was 435.58% in 2025.
  • A 5-year view of EBITDA shows it stood at -$25.1 million in 2022, then declined by 6.8% to -$26.8 million in 2023, then soared by 59.76% to -$10.8 million in 2024, then slumped by 435.58% to -$57.8 million in 2025, then gained by 12.41% to -$50.7 million in 2026.
  • The last three EBITDA figures came in at -$50.7 million (Q1 2026), -$57.8 million (Q4 2025), and -$38.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Stoke Therapeutics 1.95 Bn 1.95 Bn - -50.66 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -50.66 Mn
Dec 31, 2025 -57.84 Mn
Sep 30, 2025 -38.00 Mn
Jun 30, 2025 -23.28 Mn
Mar 31, 2025 112.93 Mn
Dec 31, 2024 -10.80 Mn
Sep 30, 2024 -26.25 Mn
Jun 30, 2024 -25.71 Mn
Mar 31, 2024 -26.35 Mn
Dec 31, 2023 -26.84 Mn
Sep 30, 2023 -24.31 Mn
Jun 30, 2023 -30.44 Mn
Mar 31, 2023 -21.97 Mn
Dec 31, 2022 -25.13 Mn
Sep 30, 2022 -26.54 Mn
Jun 30, 2022 -25.24 Mn
Mar 31, 2022 -25.17 Mn
Dec 31, 2021 -24.59 Mn
Sep 30, 2021 -22.58 Mn
Jun 30, 2021 -22.01 Mn