Stoke Therapeutics (STOK) Return on Sales (2022 - 2026)

Stoke Therapeutics' (STOK) quarterly Return on Sales came in at 0.08% in Q1 2026, down 9.0% year-on-year from 0.09% in Q1 2025, and up 81.97% quarter-over-quarter from 0.45% in Q4 2025.

Stoke Therapeutics (STOK) Return on Sales (2022 - 2026) Analysis & Trends

Stoke Therapeutics' Return on Sales history runs 5 years deep, the most recent figure standing at 0.08% for Q1 2026.

  • On a quarterly basis, Return on Sales fell 9.0% year-over-year to 0.08% in Q1 2026; TTM through Mar 2026 was 0.05%, a 6.0% decrease from a year earlier, with the FY2025 full-year figure at 0.01%, up 2.0% from the prior year.
  • Return on Sales advanced to 0.08% in Q1 2026 per STOK's latest filing, from 0.45% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.01% in Q1 2025 and bottomed at 0.58% in Q4 2023.
  • The 5-year median for Return on Sales is 0.08% (2026), against an average of 0.13%.
  • Across the five-year window, Return on Sales jumped 57 bps in 2024 and sank 44 bps in 2025, its largest moves.
  • Year by year, Return on Sales stood at 0.38% in 2022, then plunged by 52 bps to 0.58% in 2023, then jumped by 99 bps to 0.01% in 2024, then tumbled by 6731 bps to 0.45% in 2025, then jumped by 82 bps to 0.08% in 2026.
  • Per Business Quant, the three latest STOK Return on Sales figures stand at 0.08% (Q1 2026), 0.45% (Q4 2025), and 0.04% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.00%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 0.00%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Stoke Therapeutics 1.87 Bn 1.53 Bn - -0.08%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.08%
Dec 31, 2025 -0.45%
Sep 30, 2025 -0.04%
Jun 30, 2025 -0.02%
Mar 31, 2025 0.01%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.05%
Jun 30, 2024 -0.05%
Mar 31, 2024 -0.06%
Dec 31, 2023 -0.58%
Sep 30, 2023 -0.08%
Jun 30, 2023 -0.15%
Mar 31, 2023 -0.05%
Dec 31, 2022 -0.38%
Sep 30, 2022 -0.10%
Jun 30, 2022 -0.10%
Mar 31, 2022 -0.09%