Stoke Therapeutics (STOK) Operating Expenses (2018 - 2026)

Stoke Therapeutics (STOK) recorded quarterly Operating Expenses of $59.6 million in Q1 2026, up 138.27% quarter-over-quarter from -$155.9 million in Q4 2025, and up 26.03% on a YoY basis from $47.3 million in Q1 2025.

Stoke Therapeutics (STOK) Operating Expenses (2018 - 2026) Analysis & Trends

Stoke Therapeutics' Operating Expenses history runs 9 years deep, the most recent figure standing at $59.6 million for Q1 2026.

  • In Q1 2026, Operating Expenses rose 26.03% year-over-year to $59.6 million; the TTM figure through Mar 2026 stood at -$46.3 million (down 120.52% YoY), while the FY2025 annual figure was -$13.7 million, down 109.94% from the prior year.
  • Operating Expenses was $59.6 million for Q1 2026 at Stoke Therapeutics, up from -$155.9 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $147.1 million in Q4 2024 to a low of -$155.9 million in Q4 2025.
  • Historically, Operating Expenses has averaged $24.6 million across 5 years, with a median of $30.4 million in 2022.
  • Biggest YoY gain for Operating Expenses was 2468.82% in 2025; the steepest drop was 205.93% in 2025.
  • A 5-year view of Operating Expenses shows it stood at $30.4 million in 2022, then gained by 6.39% to $32.4 million in 2023, then soared by 354.33% to $147.1 million in 2024, then slumped by 205.93% to -$155.9 million in 2025, then soared by 138.27% to $59.6 million in 2026.
  • The last three Operating Expenses figures came in at $59.6 million (Q1 2026), -$155.9 million (Q4 2025), and $53.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 4.33 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -138.30 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 574,669.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.96 Bn 91.96 Bn - -67.40 Mn
10 Stoke Therapeutics 1.95 Bn 1.95 Bn - 59.65 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 59.65 Mn
Dec 31, 2025 -155.87 Mn
Sep 30, 2025 53.72 Mn
Jun 30, 2025 -3.82 Mn
Mar 31, 2025 47.33 Mn
Dec 31, 2024 147.15 Mn
Sep 30, 2024 34.90 Mn
Jun 30, 2024 -3.65 Mn
Mar 31, 2024 -2.00 Mn
Dec 31, 2023 32.39 Mn
Sep 30, 2023 30.54 Mn
Jun 30, 2023 30.78 Mn
Mar 31, 2023 29.84 Mn
Dec 31, 2022 30.44 Mn
Sep 30, 2022 30.05 Mn
Jun 30, 2022 28.47 Mn
Mar 31, 2022 27.80 Mn
Dec 31, 2021 24.53 Mn
Sep 30, 2021 22.68 Mn
Jun 30, 2021 22.03 Mn