Stoke Therapeutics (STOK) Operating Expenses (2018 - 2026)

Stoke Therapeutics' (STOK) quarterly Operating Expenses came in at $59.6 million in Q1 2026, up 26.03% year-on-year from $47.3 million in Q1 2025, and down 72.28% quarter-over-quarter from $215.2 million in Q4 2025.

Stoke Therapeutics (STOK) Operating Expenses (2018 - 2026) Analysis & Trends

Stoke Therapeutics' Operating Expenses history runs 9 years deep, the most recent figure standing at $59.6 million for Q1 2026.

  • On a quarterly basis, Operating Expenses rose 26.03% year-over-year to $59.6 million in Q1 2026; TTM through Mar 2026 was $324.8 million, a 184.39% increase from a year earlier, with the FY2025 full-year figure at $205.0 million, up 48.64% from the prior year.
  • Operating Expenses declined to $59.6 million in Q1 2026 per STOK's latest filing, from $215.2 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $215.2 million in Q4 2025 and bottomed at -$101.2 million in Q4 2023.
  • The 5-year median for Operating Expenses is $30.5 million (2023), against an average of $34.0 million.
  • Across the five-year window, Operating Expenses plunged 432.54% in 2023 and soared 1603.58% in 2025, its largest moves.
  • Year by year, Operating Expenses stood at $30.4 million in 2022, then plunged by 432.54% to -$101.2 million in 2023, then surged by 135.82% to $36.3 million in 2024, then jumped by 493.4% to $215.2 million in 2025, then tumbled by 72.28% to $59.6 million in 2026.
  • Per Business Quant, the three latest STOK Operating Expenses figures stand at $59.6 million (Q1 2026), $215.2 million (Q4 2025), and $53.7 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Stoke Therapeutics 1.86 Bn 1.51 Bn - 59.65 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 59.65 Mn
Dec 31, 2025 215.21 Mn
Sep 30, 2025 53.72 Mn
Jun 30, 2025 -3.82 Mn
Mar 31, 2025 47.33 Mn
Dec 31, 2024 36.27 Mn
Sep 30, 2024 -3.57 Mn
Jun 30, 2024 34.17 Mn
Mar 31, 2024 32.59 Mn
Dec 31, 2023 -101.24 Mn
Sep 30, 2023 30.54 Mn
Jun 30, 2023 30.78 Mn
Mar 31, 2023 29.84 Mn
Dec 31, 2022 30.44 Mn
Sep 30, 2022 30.05 Mn
Jun 30, 2022 28.47 Mn
Mar 31, 2022 27.80 Mn
Dec 31, 2021 24.53 Mn
Sep 30, 2021 22.68 Mn
Jun 30, 2021 22.03 Mn