Stoke Therapeutics (STOK) Operating Expenses (2018 - 2026)

Stoke Therapeutics' quarterly Operating Expenses came in at $59.6 million in Q1 2026, up 26.03% year-on-year from $47.3 million in Q1 2025, and up 138.27% quarter-over-quarter from -$155.9 million in Q4 2025.

Stoke Therapeutics has reported Operating Expenses for 9 years, with the latest figure at $59.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Expenses rose 26.03% year-over-year to $59.6 million; the trailing twelve-month figure through Mar 2026 stood at -$46.3 million (down 120.52% YoY), and the FY2025 full-year result was -$13.7 million, down 109.94% from the prior year.
  • Operating Expenses for Q1 2026 stood at $59.6 million, up from -$155.9 million in the prior quarter.
  • The five-year high for Operating Expenses was $147.1 million in Q4 2024, with the low at -$155.9 million in Q4 2025.
  • Average Operating Expenses over 5 years is $24.6 million, with a median of $30.4 million recorded in 2022.
  • Peak annual rise in Operating Expenses reached 2468.82% in 2025, while the deepest fall reached 205.93% in 2025.
  • Tracing STOK's Operating Expenses over 5 years: stood at $30.4 million in 2022, then advanced by 6.39% to $32.4 million in 2023, then jumped by 354.33% to $147.1 million in 2024, then sank by 205.93% to -$155.9 million in 2025, then jumped by 138.27% to $59.6 million in 2026.
  • The last three Operating Expenses figures came in at $59.6 million (Q1 2026), -$155.9 million (Q4 2025), and $53.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 2.97 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 4.33 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -138.30 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 15.76 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.85 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 898.54 Mn
10 Stoke Therapeutics 1.92 Bn 1.92 Bn - 59.65 Mn

Historic Data

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DateValue
Mar 31, 2026 59.65 Mn
Dec 31, 2025 -155.87 Mn
Sep 30, 2025 53.72 Mn
Jun 30, 2025 -3.82 Mn
Mar 31, 2025 47.33 Mn
Dec 31, 2024 147.15 Mn
Sep 30, 2024 34.90 Mn
Jun 30, 2024 -3.65 Mn
Mar 31, 2024 -2.00 Mn
Dec 31, 2023 32.39 Mn
Sep 30, 2023 30.54 Mn
Jun 30, 2023 30.78 Mn
Mar 31, 2023 29.84 Mn
Dec 31, 2022 30.44 Mn
Sep 30, 2022 30.05 Mn
Jun 30, 2022 28.47 Mn
Mar 31, 2022 27.80 Mn
Dec 31, 2021 24.53 Mn
Sep 30, 2021 22.68 Mn
Jun 30, 2021 22.03 Mn
Mar 31, 2021 16.83 Mn
Dec 31, 2020 14.59 Mn
Sep 30, 2020 13.71 Mn
Jun 30, 2020 13.01 Mn
Mar 31, 2020 11.74 Mn
Dec 31, 2019 11.07 Mn
Sep 30, 2019 9.84 Mn
Jun 30, 2019 8.45 Mn
Mar 31, 2019 6.32 Mn
Dec 31, 2018 4.54 Mn
Sep 30, 2018 3.32 Mn
Jun 30, 2018 3.01 Mn