Stoke Therapeutics (STOK) Profit After Tax (2018 - 2026)

Stoke Therapeutics' (STOK) quarterly Profit After Tax came in at -$50.0 million in Q1 2026, down 144.28% year-on-year from $112.9 million in Q1 2025, and up 14.57% quarter-over-quarter from -$58.5 million in Q4 2025.

Stoke Therapeutics (STOK) Profit After Tax (2018 - 2026) Analysis & Trends

Stoke Therapeutics' Profit After Tax history runs 9 years deep, the most recent figure standing at -$50.0 million for Q1 2026.

  • On a quarterly basis, Profit After Tax fell 144.28% year-over-year to -$50.0 million in Q1 2026; TTM through Mar 2026 was -$170.0 million, a 437.87% decrease from a year earlier, with the FY2025 full-year figure at -$6.9 million, up 92.26% from the prior year.
  • Profit After Tax rose to -$50.0 million in Q1 2026 per STOK's latest filing, from -$58.5 million in the prior quarter.
  • Across five years, Profit After Tax topped out at $112.9 million in Q1 2025 and bottomed at -$58.5 million in Q4 2025.
  • The 5-year median for Profit After Tax is -$25.7 million (2024), against an average of -$20.7 million.
  • Biggest YoY gain for Profit After Tax was 528.17% in 2025; the steepest drop was 458.4% in 2025.
  • Year by year, Profit After Tax stood at -$25.7 million in 2022, then retreated by 4.6% to -$26.8 million in 2023, then soared by 60.94% to -$10.5 million in 2024, then slumped by 458.4% to -$58.5 million in 2025, then gained by 14.57% to -$50.0 million in 2026.
  • Per Business Quant, the three latest STOK Profit After Tax figures stand at -$50.0 million (Q1 2026), -$58.5 million (Q4 2025), and -$38.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -36.84 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -65.60 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Stoke Therapeutics 1.87 Bn 1.53 Bn - -50.00 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -50.00 Mn
Dec 31, 2025 -58.53 Mn
Sep 30, 2025 -38.00 Mn
Jun 30, 2025 -23.48 Mn
Mar 31, 2025 112.93 Mn
Dec 31, 2024 -10.48 Mn
Sep 30, 2024 -26.43 Mn
Jun 30, 2024 -25.70 Mn
Mar 31, 2024 -26.37 Mn
Dec 31, 2023 -26.84 Mn
Sep 30, 2023 -24.31 Mn
Jun 30, 2023 -30.65 Mn
Mar 31, 2023 -22.55 Mn
Dec 31, 2022 -25.66 Mn
Sep 30, 2022 -26.11 Mn
Jun 30, 2022 -24.65 Mn
Mar 31, 2022 -24.65 Mn
Dec 31, 2021 -24.45 Mn
Sep 30, 2021 -22.60 Mn
Jun 30, 2021 -21.97 Mn