Stoke Therapeutics (STOK) Net Margin (2022 - 2026)
Stoke Therapeutics (STOK) posted Net Margin of -660.78% for Q2 2026, down 490.83 percentage points from -169.96% a year earlier but up 141.96 percentage points from the prior quarter.
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Analysis
Stoke Therapeutics (STOK) Net Margin (2022 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Net Margin at Stoke Therapeutics was -753.60%, down 779.85 percentage points year-over-year; for FY2025, it came in at -3.73%, up 239.68 percentage points from FY2024.
- Annual Net Margin shows a three-year change of +810.99 percentage points (FY2022 to FY2025).
- In prior years, Stoke Therapeutics' Net Margin was -243.42% in FY2024 (+949.05 pp), -1192.47% in FY2023 (-377.74 pp) and -814.73% in FY2022.
- Quarterly Net Margin has run from a low of -4132.24% in Q4 2025 to a high of 71.19% in Q1 2025 over five years.
- On a year-over-year basis, Net Margin has declined in each of the last three quarters, with an average year-over-year change of -386.87 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Net Margin in the past five years was Q4 2024, with a gain of 915.75 percentage points; the weakest was Q4 2025, with a drop of 4085.89 percentage points.
- According to Business Quant data, Net Margin for the three prior quarters was -802.75% (Q1 2026), -4132.24% (Q4 2025) and -360.68% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Stoke Therapeutics | 1.59 Bn | 421.92 Mn | - | -660.78% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -660.78% |
| Mar 31, 2026 | -802.75% |
| Dec 31, 2025 | -4,132.24% |
| Sep 30, 2025 | -360.68% |
| Jun 30, 2025 | -169.96% |
| Mar 31, 2025 | 71.19% |
| Dec 31, 2024 | -46.35% |
| Sep 30, 2024 | -540.05% |
| Jun 30, 2024 | -531.88% |
| Mar 31, 2024 | -625.57% |
| Dec 31, 2023 | -962.10% |
| Sep 30, 2023 | -741.90% |
| Jun 30, 2023 | -1,235.55% |
| Mar 31, 2023 | -437.60% |
| Dec 31, 2022 | -785.04% |
| Sep 30, 2022 | -898.83% |
| Jun 30, 2022 | -762.98% |
| Mar 31, 2022 | -821.63% |
API Access
Stoke Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=STOK&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "STOK", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=STOK&period=max&api_key=YOUR_API_KEY");
const data = await res.json();