Stoke Therapeutics (STOK) Net Margin (2022 - 2026)

Stoke Therapeutics' quarterly Net Margin came in at 802.75% in Q1 2026, down 87393.0% year-on-year from N/an in Q1 2025, and up 80.54% quarter-over-quarter from 4124.39% in Q4 2025.

Stoke Therapeutics has reported Net Margin for 5 years, with the latest figure at 802.75% in Q1 2026.

  • For the quarter ending Q1 2026, Net Margin fell 87393.0% year-over-year to 802.75%; the trailing twelve-month figure through Mar 2026 stood at 528.86% (down 55508.0% YoY), and the FY2025 full-year result was 3.71%, up 23904.0% from the prior year.
  • Net Margin for Q1 2026 stood at 802.75%, up from 4124.39% in the prior quarter.
  • The five-year high for Net Margin was 71.19% in Q1 2025, with the low at 4124.39% in Q4 2025.
  • Average Net Margin over 5 years is 811.03%, with a median of 743.14% recorded in 2023.
  • Year-over-year, Net Margin jumped 91632 bps in 2024 and slumped 407715 bps in 2025.
  • Tracing STOK's Net Margin over 5 years: stood at 786.32% in 2022, then declined by 23 bps to 963.56% in 2023, then soared by 95 bps to 47.24% in 2024, then plunged by 8631 bps to 4124.39% in 2025, then jumped by 81 bps to 802.75% in 2026.
  • The last three Net Margin figures came in at 802.75% (Q1 2026), 4124.39% (Q4 2025), and 360.68% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 0.82%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 34.53%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 20.17%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.65%
10 Stoke Therapeutics 1.92 Bn 1.92 Bn - -802.75%

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -802.75%
Dec 31, 2025 -4,124.39%
Sep 30, 2025 -360.68%
Jun 30, 2025 -169.96%
Mar 31, 2025 71.19%
Dec 31, 2024 -47.24%
Sep 30, 2024 -540.05%
Jun 30, 2024 -531.88%
Mar 31, 2024 -625.57%
Dec 31, 2023 -963.56%
Sep 30, 2023 -743.14%
Jun 30, 2023 -1,237.20%
Mar 31, 2023 -438.41%
Dec 31, 2022 -786.32%
Sep 30, 2022 -900.28%
Jun 30, 2022 -764.28%
Mar 31, 2022 -823.03%