Stoke Therapeutics (STOK) Operating Income (2018 - 2026)
Stoke Therapeutics (STOK) recorded quarterly Operating Income of -$53.4 million in Q1 2026, up 13.06% quarter-over-quarter from -$61.4 million in Q4 2025, and down 148.02% on a YoY basis from $111.2 million in Q1 2025.
Stoke Therapeutics (STOK) Operating Income (2018 - 2026) Analysis & Trends
Stoke Therapeutics' Operating Income history runs 9 years deep, the most recent figure standing at -$53.4 million for Q1 2026.
- In Q1 2026, Operating Income fell 148.02% year-over-year to -$53.4 million; the TTM figure through Mar 2026 stood at -$185.2 million (down 584.41% YoY), while the FY2025 annual figure was -$20.6 million, up 79.69% from the prior year.
- Operating Income was -$53.4 million for Q1 2026 at Stoke Therapeutics, up from -$61.4 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $111.2 million in Q1 2025 to a low of -$61.4 million in Q4 2025.
- Historically, Operating Income has averaged -$23.2 million across 5 years, with a median of -$27.3 million in 2025.
- Biggest YoY gain for Operating Income was 492.08% in 2025; the steepest drop was 350.0% in 2025.
- A 5-year view of Operating Income shows it stood at -$27.2 million in 2022, then dropped by 8.87% to -$29.6 million in 2023, then jumped by 53.85% to -$13.7 million in 2024, then plunged by 350.0% to -$61.4 million in 2025, then grew by 13.06% to -$53.4 million in 2026.
- The last three Operating Income figures came in at -$53.4 million (Q1 2026), -$61.4 million (Q4 2025), and -$43.1 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Stoke Therapeutics | 1.95 Bn | 1.95 Bn | - | -53.42 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -53.42 Mn |
| Dec 31, 2025 | -61.44 Mn |
| Sep 30, 2025 | -43.09 Mn |
| Jun 30, 2025 | -27.30 Mn |
| Mar 31, 2025 | 111.24 Mn |
| Dec 31, 2024 | -13.65 Mn |
| Sep 30, 2024 | -30.00 Mn |
| Jun 30, 2024 | -29.34 Mn |
| Mar 31, 2024 | -28.37 Mn |
| Dec 31, 2023 | -29.59 Mn |
| Sep 30, 2023 | -27.23 Mn |
| Jun 30, 2023 | -33.26 Mn |
| Mar 31, 2023 | -24.69 Mn |
| Dec 31, 2022 | -27.18 Mn |
| Sep 30, 2022 | -27.15 Mn |
| Jun 30, 2022 | -25.24 Mn |
| Mar 31, 2022 | -24.80 Mn |
| Dec 31, 2021 | -24.53 Mn |
| Sep 30, 2021 | -22.68 Mn |
| Jun 30, 2021 | -22.03 Mn |