Stoke Therapeutics (STOK) Operating Income (2018 - 2026)

Stoke Therapeutics (STOK) recorded quarterly Operating Income of -$53.4 million in Q1 2026, up 13.06% quarter-over-quarter from -$61.4 million in Q4 2025, and down 148.02% on a YoY basis from $111.2 million in Q1 2025.

Stoke Therapeutics (STOK) Operating Income (2018 - 2026) Analysis & Trends

Stoke Therapeutics' Operating Income history runs 9 years deep, the most recent figure standing at -$53.4 million for Q1 2026.

  • In Q1 2026, Operating Income fell 148.02% year-over-year to -$53.4 million; the TTM figure through Mar 2026 stood at -$185.2 million (down 584.41% YoY), while the FY2025 annual figure was -$20.6 million, up 79.69% from the prior year.
  • Operating Income was -$53.4 million for Q1 2026 at Stoke Therapeutics, up from -$61.4 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $111.2 million in Q1 2025 to a low of -$61.4 million in Q4 2025.
  • Historically, Operating Income has averaged -$23.2 million across 5 years, with a median of -$27.3 million in 2025.
  • Biggest YoY gain for Operating Income was 492.08% in 2025; the steepest drop was 350.0% in 2025.
  • A 5-year view of Operating Income shows it stood at -$27.2 million in 2022, then dropped by 8.87% to -$29.6 million in 2023, then jumped by 53.85% to -$13.7 million in 2024, then plunged by 350.0% to -$61.4 million in 2025, then grew by 13.06% to -$53.4 million in 2026.
  • The last three Operating Income figures came in at -$53.4 million (Q1 2026), -$61.4 million (Q4 2025), and -$43.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Stoke Therapeutics 1.95 Bn 1.95 Bn - -53.42 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -53.42 Mn
Dec 31, 2025 -61.44 Mn
Sep 30, 2025 -43.09 Mn
Jun 30, 2025 -27.30 Mn
Mar 31, 2025 111.24 Mn
Dec 31, 2024 -13.65 Mn
Sep 30, 2024 -30.00 Mn
Jun 30, 2024 -29.34 Mn
Mar 31, 2024 -28.37 Mn
Dec 31, 2023 -29.59 Mn
Sep 30, 2023 -27.23 Mn
Jun 30, 2023 -33.26 Mn
Mar 31, 2023 -24.69 Mn
Dec 31, 2022 -27.18 Mn
Sep 30, 2022 -27.15 Mn
Jun 30, 2022 -25.24 Mn
Mar 31, 2022 -24.80 Mn
Dec 31, 2021 -24.53 Mn
Sep 30, 2021 -22.68 Mn
Jun 30, 2021 -22.03 Mn