Stoke Therapeutics STOK
NASDAQ STOK
$29.54 -0.45 (-1.50%)
As of: Sep 4, 2026 · 12:50 PM EDT

Stoke Therapeutics (STOK) Operating Income (2018 - 2026)

Stoke Therapeutics (STOK) posted quarterly Operating Income of -$53.4 million for Q1 2026, down 148.02% year-over-year from $111.2 million in Q1 2025, and up 13.06% quarter-over-quarter from -$61.4 million in Q4 2025.

Analysis

Stoke Therapeutics (STOK) Operating Income (2018 - 2026) Analysis & Trends

Stoke Therapeutics' Operating Income history runs 9 years deep, the most recent figure standing at -$53.4 million for Q1 2026.

  • In Q1 2026, Operating Income fell 148.02% year-over-year to -$53.4 million; the TTM figure through Mar 2026 stood at -$185.2 million (down 584.41% YoY), while the FY2025 annual figure was -$20.6 million, up 79.69% from the prior year.
  • Operating Income for Q1 2026 stood at -$53.4 million, up from -$61.4 million in the prior quarter.
  • The five-year high for Operating Income was $111.2 million in Q1 2025, with the low at -$61.4 million in Q4 2025.
  • The 5-year median for Operating Income is -$27.3 million (2025), against an average of -$23.2 million.
  • Peak annual rise in Operating Income reached 492.08% in 2025, while the deepest fall reached 350.0% in 2025.
  • Stoke Therapeutics' Operating Income stood at -$27.2 million in 2022, then slipped by 8.87% to -$29.6 million in 2023, then soared by 53.85% to -$13.7 million in 2024, then tumbled by 350.0% to -$61.4 million in 2025, then climbed by 13.06% to -$53.4 million in 2026.
  • Business Quant data shows STOK's Operating Income at -$53.4 million in Q1 2026, -$61.4 million in Q4 2025, and -$43.1 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 139.62 Bn 131.77 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.73 Bn 77.73 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.53 Bn 58.35 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.23 Bn 53.09 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.05 Bn 44.05 Bn - -505.13 Mn
6 BeOne Medicines 40.03 Bn 34.93 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.50 Bn 32.19 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.52 Bn 27.68 Bn - 133.12 Mn
9 Insmed 27.46 Bn 26.30 Bn 358.27 Mn -1.55 Mn
10 Stoke Therapeutics 1.95 Bn 1.66 Bn - -65.43 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -65.43 Mn
Mar 31, 2026 -53.42 Mn
Dec 31, 2025 -61.44 Mn
Sep 30, 2025 -43.09 Mn
Jun 30, 2025 -27.30 Mn
Mar 31, 2025 111.24 Mn
Dec 31, 2024 -13.65 Mn
Sep 30, 2024 -30.00 Mn
Jun 30, 2024 -29.34 Mn
Mar 31, 2024 -28.37 Mn
Dec 31, 2023 -29.59 Mn
Sep 30, 2023 -27.23 Mn
Jun 30, 2023 -33.26 Mn
Mar 31, 2023 -24.69 Mn
Dec 31, 2022 -27.18 Mn
Sep 30, 2022 -27.15 Mn
Jun 30, 2022 -25.24 Mn
Mar 31, 2022 -24.80 Mn
Dec 31, 2021 -24.53 Mn
Sep 30, 2021 -22.68 Mn