ProQR Therapeutics (PRQR) EBT Margin (2021 - 2026)
ProQR Therapeutics (PRQR) recorded EBT Margin of -99.36% in the quarter ended Jun 30, 2026, up 219.24 percentage points from -318.60% a year earlier and up 558.93 percentage points from the prior quarter.
ProQR Therapeutics (PRQR) EBT Margin (2021 - 2026) Analysis & Trends
On a TTM basis, ProQR Therapeutics' EBT Margin came in at -229.26% as of Jun 30, 2026, up 12.21 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -265.09%, down 117.19 percentage points from the prior year.
- Annual EBT Margin has a four-year change of +4280.38 percentage points (years ended Dec 2021 to Dec 2025).
- Across earlier years, EBT Margin came in at -147.90% in the year ended Dec 31, 2024 (+279.08 pp), -426.97% in the year ended Dec 31, 2023 (+1356.78 pp), -1783.75% in the year ended Dec 31, 2022 (+2761.72 pp) and -4545.47% in the year ended Dec 31, 2021.
- The figure for the quarter ended Jun 30, 2026 is the highest quarterly EBT Margin since the quarter ended Jun 30, 2024.
- On a year-over-year basis, EBT Margin rose in three of the last eight quarters, with an average year-over-year change of -68.31 percentage points.
- Peak year-over-year performance for EBT Margin in the last five years was a gain of 5775.37 percentage points in the quarter ended Dec 31, 2022, against a drop of 1130.34 percentage points in the quarter ended Sep 30, 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -658.29% (quarter ended Mar 31, 2026), -190.25% (quarter ended Dec 31, 2025) and -381.89% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 26.66% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 25.18% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -4.11% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 29.63% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.19% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 27.53% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -131.41% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -4.34% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 41.75% |
| 10 | ProQR Therapeutics | 173.85 Mn | -289.75 Mn | - | -99.36% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -99.36% |
| Mar 31, 2026 | -658.29% |
| Dec 31, 2025 | -190.25% |
| Sep 30, 2025 | -381.89% |
| Jun 30, 2025 | -318.60% |
| Mar 31, 2025 | -223.04% |
| Dec 31, 2024 | -216.04% |
| Sep 30, 2024 | -210.98% |
| Jun 30, 2024 | -45.87% |
| Mar 31, 2024 | -172.02% |
| Dec 31, 2023 | -166.81% |
| Sep 30, 2023 | -398.61% |
| Jun 30, 2023 | -665.48% |
| Mar 31, 2023 | -1,351.91% |
| Dec 31, 2022 | -1,847.22% |
| Sep 30, 2022 | -2,854.42% |
| Jun 30, 2022 | -1,447.63% |
| Mar 31, 2022 | -1,248.67% |
| Dec 31, 2021 | -7,622.59% |
| Sep 30, 2021 | -1,724.08% |
ProQR Therapeutics EBT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebt-margin&ticker=PRQR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebt-margin", "ticker": "PRQR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebt-margin&ticker=PRQR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();