ProQR Therapeutics N.V. (PRQR) Operating Margin (2021 - 2026)
ProQR Therapeutics (PRQR) reported Operating Margin of -100.72% for the quarter ended Jun 30, 2026, up 220.19 percentage points from -320.91% a year earlier and up 570.65 percentage points from the prior quarter.
ProQR Therapeutics N.V. (PRQR) Operating Margin (2021 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, ProQR Therapeutics' Operating Margin came in at -233.85%, up 20.87 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -273.14%, down 111.96 percentage points from the prior year.
- Operating Margin has a four-year change of +4012.25 percentage points (years ended Dec 2021 to Dec 2025).
- By year, Operating Margin came in at -161.18% in the year ended Dec 31, 2024 (+327.90 pp), -489.09% in the year ended Dec 31, 2023 (+1323.91 pp), -1812.99% in the year ended Dec 31, 2022 (+2472.40 pp) and -4285.39% in the year ended Dec 31, 2021.
- The figure for the quarter ended Jun 30, 2026 ranks as the highest quarterly Operating Margin since the quarter ended Jun 30, 2024.
- Year over year, Operating Margin gained in three of the last eight quarters, with an average year-over-year change of -48.60 percentage points.
- The high point for year-over-year Operating Margin in five years was the quarter ended Dec 31, 2022 (a gain of 5519.65 percentage points); the low point was the quarter ended Sep 30, 2022 (a drop of 765.88 percentage points).
- Per Business Quant data, the three quarters before the quarter ended Jun 30, 2026 came in at -671.37% (quarter ended Mar 31, 2026), -194.05% (quarter ended Dec 31, 2025) and -391.53% (quarter ended Sep 30, 2025).
Peer Comparison
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -100.72% |
| Mar 31, 2026 | -671.37% |
| Dec 31, 2025 | -194.05% |
| Sep 30, 2025 | -391.53% |
| Jun 30, 2025 | -320.91% |
| Mar 31, 2025 | -239.34% |
| Dec 31, 2024 | -234.06% |
| Sep 30, 2024 | -226.80% |
| Jun 30, 2024 | -57.10% |
| Mar 31, 2024 | -181.46% |
| Dec 31, 2023 | -190.86% |
| Sep 30, 2023 | -539.49% |
| Jun 30, 2023 | -731.20% |
| Mar 31, 2023 | -1,433.44% |
| Dec 31, 2022 | -1,730.56% |
| Sep 30, 2022 | -2,435.26% |
| Jun 30, 2022 | -1,702.37% |
| Mar 31, 2022 | -1,508.32% |
| Dec 31, 2021 | -7,250.21% |
| Sep 30, 2021 | -1,669.38% |
ProQR Therapeutics N.V. Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=PRQR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "PRQR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=PRQR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();