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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Sales

ProQR Therapeutics (PRQR) Operating Margin (2021 - 2025)

ProQR Therapeutics' Operating Margin history spans 5 years, with the latest figure at 194.05% for Q4 2025.

  • On a quarterly basis, Operating Margin rose 4001.0% to 194.05% in Q4 2025 year-over-year; TTM through Dec 2025 was 273.87%, a 11251.0% decrease, with the full-year FY2025 number at 273.14%, down 11196.0% from a year prior.
  • Operating Margin hit 194.05% in Q4 2025 for ProQR Therapeutics, up from 391.53% in the prior quarter.
  • Over the last five years, Operating Margin for PRQR hit a ceiling of 57.1% in Q2 2024 and a floor of 7250.21% in Q4 2021.
  • Historically, Operating Margin has averaged 1393.14% across 5 years, with a median of 539.49% in 2023.
  • The widest YoY moves for Operating Margin: up 551965bps in 2022, down -76588bps in 2022.
  • Tracing PRQR's Operating Margin over 5 years: stood at 7250.21% in 2021, then surged by 76bps to 1730.56% in 2022, then surged by 89bps to 190.86% in 2023, then fell by -23bps to 234.06% in 2024, then increased by 17bps to 194.05% in 2025.
  • Business Quant data shows Operating Margin for PRQR at 194.05% in Q4 2025, 391.53% in Q3 2025, and 320.91% in Q2 2025.