ProQR Therapeutics N.V. (PRQR) Institutional Ownership

Institutions by Trading Activity

105,344,996Shares Outstanding

37,015,434Shares held by institutions

$60,705,312Value of institutional holdings

35.14%Institutional ownership %

5.28%Shares Changed QoQ

64No. of institutional investors

ProQR Therapeutics N.V. (NASDAQ:PRQR) showed up in the 13F filings of 63 institutional investors as of December 2025.

Collectively, these holders controlled 35.1% of ProQR Therapeutics's outstanding shares in December 2025, down from 35.6% in September 2025.
They increased total shares held in ProQR Therapeutics by 5.28% from last quarter, and the number of investors in PRQR decreased 16.0% annually.
Of these 63 funds, 32 grew their exposure to ProQR Therapeutics, 12 cut back, and 19 maintained positions.
Institutional investors collectively held 37.02Mn shares in ProQR Therapeutics as of December 2025, up by 1.86Mn shares quarter on quarter, and down 8.03Mn shares year over year.
MOODY LYNN LIEBERSON & WALKER, LLC holds the largest position in PRQR at 25.0K shares as of December 31, 2025, or 0.02% of shares outstanding.
Top purchasers of PRQR stock for the quarter ending December 2025 included Hilton Head Capital Partners, LLC (1.4K).
Leading sellers of ProQR Therapeutics shares for the quarter ending December 2025 were RFG Advisory, LLC (11.0K).
Per Business Quant data, the top 6 holders of ProQR Therapeutics for the quarter ending December 2025 are MOODY LYNN LIEBERSON & WALKER, LLC (25.0K), RFG Advisory, LLC (19.0K), Hilton Head Capital Partners, LLC (1.4K), Farther Finance Advisors, LLC (1.0K), PFS Partners, LLC (1.0K), Medallion Wealth Advisors, LLC (10).

37,015,434 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	6,253,467	0	0.00%	$12,632,003.00
Privium Fund Management B.V.	31 Dec, 2025	5,357,762	359,475	7.19%	$10,822,680.00
Aberdeen Group plc	31 Dec, 2025	2,950,676	651,853	28.36%	$5,960,366.00
Affinity Asset Advisors, LLC	31 Dec, 2025	2,454,278	-1,145,722	-31.83%	$4,957,642.00
Sio Capital Management, LLC	31 Dec, 2025	2,164,181	89,042	4.29%	$4,371,646.00
DAFNA Capital Management LLC	31 Dec, 2025	1,567,561	0	0.00%	$3,166,473.00
Kynam Capital Management, LP	31 Dec, 2025	1,566,317	-83,145	-5.04%	$3,163,960.00
Ikarian Capital, LLC	31 Dec, 2025	1,492,229	600,000	67.25%	$3,014,301.00
Morgan Stanley	31 Dec, 2025	1,367,119	-1,534,083	-52.88%	$2,761,581.00
PLATINUM INVESTMENT MANAGEMENT LTD	31 Dec, 2025	1,235,514	0	0.00%	$2,495,738.00
ArrowMark Colorado Holdings LLC	31 Dec, 2025	1,164,722	-81,512	-6.54%	$2,352,738.00
M28 Capital Management LP	31 Dec, 2025	1,019,498	0	0.00%	$2,059,386.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	839,384	422,084	101.15%	$1,695,556.00
Point72 Asset Management, L.P.	31 Dec, 2025	813,650	63,650	8.49%	$1,643,573.00
UBS Group AG	31 Dec, 2025	797,664	703,114	743.64%	$1,611,282.00
NOMURA ASSET MANAGEMENT INTERNATIONAL INC.	31 Dec, 2025	620,000	620,000	0.00%	$1,252,000.00
Walleye Capital LLC	31 Dec, 2025	591,785	59,808	11.24%	$1,195,406.00
CITADEL ADVISORS LLC	31 Dec, 2025	583,222	-73,790	-11.23%	$1,178,108.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	452,400	223,800	97.90%	$913,848.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	434,991	194,369	80.78%	$878,682.00

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