ProQR Therapeutics (PRQR) Retained Earnings (2013 - 2025)
ProQR Therapeutics (PRQR) posted Retained Earnings of -$544.2 million for Q4 2025, down 19.22% sequentially from -$456.5 million in Q4 2024, and down 19.22% YoY from -$673.7 million in Q4 2024.
ProQR Therapeutics (PRQR) Retained Earnings (2013 - 2025) Analysis & Trends
ProQR Therapeutics has reported Retained Earnings for 13 years, with the latest figure at -$544.2 million in Q4 2025.
- Quarterly Retained Earnings fell 19.22% year-over-year to -$544.2 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$544.2 million (down 19.22% YoY) and the FY2025 annual result came in at -$544.2 million, down 19.22% from the prior year.
- Retained Earnings retreated to -$544.2 million in Q4 2025 per PRQR's latest filing, from -$456.5 million in the prior quarter.
- Over five years, Retained Earnings peaked at -$363.5 million in Q4 2021 and troughed at -$544.2 million in Q4 2025.
- A 5-year average of -$436.5 million and a median of -$431.3 million in 2023 frame the typical range for Retained Earnings.
- The sharpest annual moves came in 2024 and 2025: Retained Earnings fell 5.84% in 2024, then decreased 19.22% in 2025.
- Over 5 years, Retained Earnings stood at -$363.5 million in 2021, then declined by 6.4% to -$386.8 million in 2022, then fell by 11.51% to -$431.3 million in 2023, then dropped by 5.84% to -$456.5 million in 2024, then slipped by 19.22% to -$544.2 million in 2025.
- According to Business Quant data, Retained Earnings over the past three periods registered -$544.2 million, -$456.5 million, and -$431.3 million for Q4 2025, Q4 2024, and Q4 2023 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Retained Earnings (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 15.69 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 37.62 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 1.41 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -4.00 Bn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 13.05 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -104.13 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 4.38 Bn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -6.33 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 6.57 Bn |
| 10 | ProQR Therapeutics | 206.80 Mn | 111.86 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -544.20 Mn |
| Dec 31, 2024 | -456.46 Mn |
| Dec 31, 2023 | -431.29 Mn |
| Dec 31, 2022 | -386.78 Mn |
| Dec 31, 2021 | -363.52 Mn |
| Dec 31, 2020 | -307.31 Mn |
| Dec 31, 2019 | -234.38 Mn |
| Dec 31, 2018 | -177.42 Mn |
| Dec 31, 2017 | -140.55 Mn |
| Dec 31, 2016 | -81.77 Mn |
| Dec 31, 2015 | -40.15 Mn |
| Dec 31, 2014 | -19.74 Mn |
| Dec 31, 2013 | -5.00 Mn |