ProQR Therapeutics (PRQR) Retained Earnings (2013 - 2025)

ProQR Therapeutics (PRQR) posted Retained Earnings of -$544.2 million for Q4 2025, down 19.22% sequentially from -$456.5 million in Q4 2024, and down 19.22% YoY from -$673.7 million in Q4 2024.

ProQR Therapeutics (PRQR) Retained Earnings (2013 - 2025) Analysis & Trends

ProQR Therapeutics has reported Retained Earnings for 13 years, with the latest figure at -$544.2 million in Q4 2025.

  • Quarterly Retained Earnings fell 19.22% year-over-year to -$544.2 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$544.2 million (down 19.22% YoY) and the FY2025 annual result came in at -$544.2 million, down 19.22% from the prior year.
  • Retained Earnings retreated to -$544.2 million in Q4 2025 per PRQR's latest filing, from -$456.5 million in the prior quarter.
  • Over five years, Retained Earnings peaked at -$363.5 million in Q4 2021 and troughed at -$544.2 million in Q4 2025.
  • A 5-year average of -$436.5 million and a median of -$431.3 million in 2023 frame the typical range for Retained Earnings.
  • The sharpest annual moves came in 2024 and 2025: Retained Earnings fell 5.84% in 2024, then decreased 19.22% in 2025.
  • Over 5 years, Retained Earnings stood at -$363.5 million in 2021, then declined by 6.4% to -$386.8 million in 2022, then fell by 11.51% to -$431.3 million in 2023, then dropped by 5.84% to -$456.5 million in 2024, then slipped by 19.22% to -$544.2 million in 2025.
  • According to Business Quant data, Retained Earnings over the past three periods registered -$544.2 million, -$456.5 million, and -$431.3 million for Q4 2025, Q4 2024, and Q4 2023 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 15.69 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 37.62 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.41 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -4.00 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.05 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -104.13 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 4.38 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -6.33 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 6.57 Bn
10 ProQR Therapeutics 206.80 Mn 111.86 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -544.20 Mn
Dec 31, 2024 -456.46 Mn
Dec 31, 2023 -431.29 Mn
Dec 31, 2022 -386.78 Mn
Dec 31, 2021 -363.52 Mn
Dec 31, 2020 -307.31 Mn
Dec 31, 2019 -234.38 Mn
Dec 31, 2018 -177.42 Mn
Dec 31, 2017 -140.55 Mn
Dec 31, 2016 -81.77 Mn
Dec 31, 2015 -40.15 Mn
Dec 31, 2014 -19.74 Mn
Dec 31, 2013 -5.00 Mn