ProQR Therapeutics (PRQR) EBIT (2013 - 2025)
ProQR Therapeutics (PRQR) reported EBIT of -$10.1 million for Q4 2025, down 37.07% on a YoY basis from -$16.1 million in Q4 2024, and up 22.52% sequentially from -$13.0 million in Q3 2025.
ProQR Therapeutics (PRQR) EBIT (2013 - 2025) Analysis & Trends
ProQR Therapeutics (PRQR) has 13 years of EBIT data on file, last reported at -$10.1 million in Q4 2025.
- For the quarter ending Q4 2025, EBIT fell 37.07% year-over-year to -$10.1 million; the trailing twelve-month figure through Dec 2025 stood at -$47.7 million (down 68.34% YoY), and the FY2025 full-year result was -$50.6 million, down 55.31% from the prior year.
- EBIT improved to -$10.1 million in Q4 2025, from -$13.0 million in the prior quarter.
- In the past five years, EBIT ranged from a high of -$3.3 million in Q2 2024 to a low of -$24.5 million in Q3 2022.
- A 5-year average of -$12.3 million and a median of -$10.5 million in 2025 frame the typical range for EBIT.
- Across the five-year window, EBIT plunged 329.6% in 2021 and jumped 75.76% in 2023, its largest moves.
- Tracing PRQR's EBIT over 5 years: stood at -$21.5 million in 2021, then jumped by 74.76% to -$5.4 million in 2022, then plunged by 35.1% to -$7.3 million in 2023, then retreated by 0.78% to -$7.4 million in 2024, then plunged by 37.07% to -$10.1 million in 2025.
- Business Quant data shows PRQR's EBIT at -$10.1 million in Q4 2025, -$13.0 million in Q3 2025, and -$13.8 million in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | ProQR Therapeutics | 182.23 Mn | 138.42 Mn | - | -10.11 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -10.11 Mn |
| Sep 30, 2025 | -13.04 Mn |
| Jun 30, 2025 | -13.77 Mn |
| Mar 31, 2025 | -10.82 Mn |
| Dec 31, 2024 | -7.37 Mn |
| Sep 30, 2024 | -9.14 Mn |
| Jun 30, 2024 | -3.32 Mn |
| Mar 31, 2024 | -8.52 Mn |
| Dec 31, 2023 | -7.32 Mn |
| Sep 30, 2023 | -5.94 Mn |
| Jun 30, 2023 | -8.73 Mn |
| Mar 31, 2023 | -9.50 Mn |
| Dec 31, 2022 | -5.42 Mn |
| Sep 30, 2022 | -24.53 Mn |
| Jun 30, 2022 | -15.69 Mn |
| Mar 31, 2022 | -17.20 Mn |
| Dec 31, 2021 | -21.45 Mn |
| Sep 30, 2021 | -18.39 Mn |
| Jun 30, 2021 | -19.60 Mn |
| Mar 31, 2021 | -15.91 Mn |