ProQR Therapeutics (PRQR) EBIT (2013 - 2025)

ProQR Therapeutics (PRQR) reported EBIT of -$10.1 million for Q4 2025, down 37.07% on a YoY basis from -$16.1 million in Q4 2024, and up 22.52% sequentially from -$13.0 million in Q3 2025.

ProQR Therapeutics (PRQR) EBIT (2013 - 2025) Analysis & Trends

ProQR Therapeutics (PRQR) has 13 years of EBIT data on file, last reported at -$10.1 million in Q4 2025.

  • For the quarter ending Q4 2025, EBIT fell 37.07% year-over-year to -$10.1 million; the trailing twelve-month figure through Dec 2025 stood at -$47.7 million (down 68.34% YoY), and the FY2025 full-year result was -$50.6 million, down 55.31% from the prior year.
  • EBIT improved to -$10.1 million in Q4 2025, from -$13.0 million in the prior quarter.
  • In the past five years, EBIT ranged from a high of -$3.3 million in Q2 2024 to a low of -$24.5 million in Q3 2022.
  • A 5-year average of -$12.3 million and a median of -$10.5 million in 2025 frame the typical range for EBIT.
  • Across the five-year window, EBIT plunged 329.6% in 2021 and jumped 75.76% in 2023, its largest moves.
  • Tracing PRQR's EBIT over 5 years: stood at -$21.5 million in 2021, then jumped by 74.76% to -$5.4 million in 2022, then plunged by 35.1% to -$7.3 million in 2023, then retreated by 0.78% to -$7.4 million in 2024, then plunged by 37.07% to -$10.1 million in 2025.
  • Business Quant data shows PRQR's EBIT at -$10.1 million in Q4 2025, -$13.0 million in Q3 2025, and -$13.8 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 ProQR Therapeutics 182.23 Mn 138.42 Mn - -10.11 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -10.11 Mn
Sep 30, 2025 -13.04 Mn
Jun 30, 2025 -13.77 Mn
Mar 31, 2025 -10.82 Mn
Dec 31, 2024 -7.37 Mn
Sep 30, 2024 -9.14 Mn
Jun 30, 2024 -3.32 Mn
Mar 31, 2024 -8.52 Mn
Dec 31, 2023 -7.32 Mn
Sep 30, 2023 -5.94 Mn
Jun 30, 2023 -8.73 Mn
Mar 31, 2023 -9.50 Mn
Dec 31, 2022 -5.42 Mn
Sep 30, 2022 -24.53 Mn
Jun 30, 2022 -15.69 Mn
Mar 31, 2022 -17.20 Mn
Dec 31, 2021 -21.45 Mn
Sep 30, 2021 -18.39 Mn
Jun 30, 2021 -19.60 Mn
Mar 31, 2021 -15.91 Mn