ProQR Therapeutics (PRQR) Return on Sales (2021 - 2025)

ProQR Therapeutics' Return on Sales history runs 5 years deep, the most recent figure standing at 0.02% for Q4 2025.

• In Q4 2025, Return on Sales changed 0.0% year-over-year to 0.02%; the TTM figure through Dec 2025 stood at 0.03% (down 1.0% YoY), while the FY2025 annual figure was 0.03%, down 1.0% from the prior year.
• Return on Sales came in at 0.02% for Q4 2025 at ProQR Therapeutics, up from 0.04% in the prior quarter.
• In the past five years, Return on Sales ranged from a high of 0.01% in Q2 2024 to a low of 0.73% in Q4 2021.
• A 5-year average of 0.14% and a median of 0.05% in 2023 frame the typical range for Return on Sales.
• On a YoY basis, Return on Sales climbed as much as 55 bps in 2022 and fell as far as 8 bps in 2022.
• ProQR Therapeutics' Return on Sales stood at 0.73% in 2021, then soared by 76 bps to 0.17% in 2022, then surged by 89 bps to 0.02% in 2023, then dropped by 23 bps to 0.02% in 2024, then increased by 17 bps to 0.02% in 2025.
• According to Business Quant data, Return on Sales over the past three periods registered 0.02%, 0.04%, and 0.03% for Q4 2025, Q3 2025, and Q2 2025 respectively.

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