ProQR Therapeutics (PRQR) Net Margin (2021 - 2026)
ProQR Therapeutics' Net Margin was -99.65% in the quarter ended Jun 30, 2026, up 219.43 percentage points from -319.07% a year earlier and up 558.64 percentage points from the prior quarter.
ProQR Therapeutics (PRQR) Net Margin (2021 - 2026) Analysis & Trends
On a trailing twelve-month basis, ProQR Therapeutics' Net Margin was -229.40% through Jun 30, 2026, up 12.18 percentage points year-over-year; for the year ended Dec 31, 2025, it came in at -265.21%, down 118.35 percentage points from the prior year.
- Net Margin shows a four-year change of +4289.02 percentage points (years ended Dec 2021 to Dec 2025).
- In earlier years, Net Margin was -146.86% in the year ended Dec 31, 2024 (+278.92 pp), -425.78% in the year ended Dec 31, 2023 (+1360.65 pp), -1786.42% in the year ended Dec 31, 2022 (+2767.81 pp) and -4554.23% in the year ended Dec 31, 2021.
- The figure for the quarter ended Jun 30, 2026 marks the highest quarterly Net Margin since the quarter ended Jun 30, 2024.
- Compared with a year earlier, Net Margin was higher in three of the last eight quarters, with an average year-over-year change of -66.44 percentage points.
- The best year-over-year quarter for Net Margin over five years was the quarter ended Dec 31, 2022 (a gain of 5784.58 percentage points); the worst was the quarter ended Sep 30, 2022 (a drop of 1134.80 percentage points).
- Per Business Quant data, PRQR's Net Margin in the three quarters before the quarter ended Jun 30, 2026 was -658.29% (quarter ended Mar 31, 2026), -190.27% (quarter ended Dec 31, 2025) and -381.89% (quarter ended Sep 30, 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | ProQR Therapeutics | 173.85 Mn | -289.75 Mn | - | -99.65% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -99.65% |
| Mar 31, 2026 | -658.29% |
| Dec 31, 2025 | -190.27% |
| Sep 30, 2025 | -381.89% |
| Jun 30, 2025 | -319.07% |
| Mar 31, 2025 | -223.04% |
| Dec 31, 2024 | -216.04% |
| Sep 30, 2024 | -210.98% |
| Jun 30, 2024 | -42.70% |
| Mar 31, 2024 | -172.09% |
| Dec 31, 2023 | -166.96% |
| Sep 30, 2023 | -416.79% |
| Jun 30, 2023 | -661.99% |
| Mar 31, 2023 | -1,351.91% |
| Dec 31, 2022 | -1,847.22% |
| Sep 30, 2022 | -2,862.90% |
| Jun 30, 2022 | -1,449.78% |
| Mar 31, 2022 | -1,249.29% |
| Dec 31, 2021 | -7,631.80% |
| Sep 30, 2021 | -1,728.10% |
ProQR Therapeutics Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=PRQR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "PRQR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=PRQR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();