ProQR Therapeutics (PRQR) Net Margin (2021 - 2026)
ProQR Therapeutics (PRQR) posted Net Margin of 658.29% for Q1 2026, down 293.43% sequentially from 167.32% in Q4 2025, and down 43525.0% YoY from N/an in Q1 2025.
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ProQR Therapeutics (PRQR) Net Margin (2021 - 2026) Analysis & Trends
ProQR Therapeutics has reported Net Margin for 15 years, with the latest figure at 658.29% in Q1 2026.
- Quarterly Net Margin fell 43525.0% year-over-year to 658.29% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 336.51% (down 17617.0% YoY) and the FY2025 annual result came in at 265.21%, down 11835.0% from the prior year.
- Net Margin retreated to 658.29% in Q1 2026 per PRQR's latest filing, from 167.32% in the prior quarter.
- Over five years, Net Margin peaked at 42.7% in Q2 2024 and troughed at 2864.62% in Q3 2022.
- A 5-year average of 735.46% and a median of 382.69% in 2025 frame the typical range for Net Margin.
- The widest YoY moves for Net Margin: up 577704 bps in 2022, down 114442 bps in 2022.
- Over 5 years, Net Margin stood at 1846.81% in 2022, then jumped by 92 bps to 150.3% in 2023, then sank by 42 bps to 213.7% in 2024, then climbed by 22 bps to 167.32% in 2025, then plunged by 293 bps to 658.29% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 658.29%, 167.32%, and 382.69% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 32.99% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 30.23% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 31.16% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -539.31% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 13.90% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 12.74% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 12.09% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -3.12% |
| 10 | ProQR Therapeutics | 218.57 Mn | 82.18 Mn | - | -99.65% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -99.65% |
| Mar 31, 2026 | -658.29% |
| Dec 31, 2025 | -186.53% |
| Sep 30, 2025 | -381.89% |
| Jun 30, 2025 | -319.07% |
| Mar 31, 2025 | -223.04% |
| Dec 31, 2024 | -216.04% |
| Sep 30, 2024 | -210.98% |
| Jun 30, 2024 | -42.70% |
| Mar 31, 2024 | -172.09% |
| Dec 31, 2023 | -166.96% |
| Sep 30, 2023 | -416.79% |
| Jun 30, 2023 | -663.32% |
| Mar 31, 2023 | -1,363.82% |
| Dec 31, 2022 | -1,846.81% |
| Sep 30, 2022 | -2,864.62% |
| Jun 30, 2022 | -1,473.12% |
| Mar 31, 2022 | -1,248.58% |
| Dec 31, 2021 | -7,623.85% |
| Sep 30, 2021 | -1,725.57% |