Growth Metrics

ProQR Therapeutics (PRQR) Invested Capital (2013 - 2025)

ProQR Therapeutics recorded quarterly Invested Capital of $70.4 million in Q4 2025, down 34.91% quarter-over-quarter from $108.1 million in Q4 2024, and down 34.91% year-over-year from $108.1 million in Q4 2024.

ProQR Therapeutics' Invested Capital history runs 13 years deep, the most recent figure standing at $70.4 million for Q4 2025.

  • In Q4 2025, Invested Capital fell 34.91% year-over-year to $70.4 million; the TTM figure through Dec 2025 stood at $70.4 million (down 34.91% YoY), while the FY2025 annual figure was $70.4 million, down 34.91% from the prior year.
  • Invested Capital came in at $70.4 million for Q4 2025 at ProQR Therapeutics, down from $108.1 million in the prior quarter.
  • In the past five years, Invested Capital ranged from a high of $175.8 million in Q4 2021 to a low of $79903.5 in Q1 2021.
  • A 5-year average of $98.2 million and a median of $77.0 million in 2022 frame the typical range for Invested Capital.
  • Across the five-year window, Invested Capital slumped 99.92% in 2021 and soared 195418.42% in 2022, its largest moves.
  • ProQR Therapeutics' Invested Capital stood at $175.8 million in 2021, then sank by 52.47% to $83.5 million in 2022, then dropped by 26.8% to $61.1 million in 2023, then surged by 76.84% to $108.1 million in 2024, then sank by 34.91% to $70.4 million in 2025.
  • According to Business Quant data, Invested Capital over the past three periods registered $70.4 million, $108.1 million, and $61.1 million for Q4 2025, Q4 2024, and Q4 2023 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 595,226.00
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - 110.96 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 14.38 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 19.36 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 31.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 1.08 Bn
10 ProQR Therapeutics 174.11 Mn 66.54 Mn - 70.39 Mn

Historic Data

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DateValue
Dec 31, 2025 70.39 Mn
Dec 31, 2024 108.14 Mn
Dec 31, 2023 61.15 Mn
Sep 30, 2023 53.59 Mn
Jun 30, 2023 60.29 Mn
Mar 31, 2023 67.52 Mn
Dec 31, 2022 83.54 Mn
Sep 30, 2022 70.27 Mn
Jun 30, 2022 133.54 Mn
Mar 31, 2022 156.23 Mn
Dec 31, 2021 175.77 Mn
Sep 30, 2021 172.32 Mn
Jun 30, 2021 162.67 Mn
Mar 31, 2021 79,903.49
Dec 31, 2020 71.09 Mn
Sep 30, 2020 99.52 Mn
Jun 30, 2020 93.62 Mn
Mar 31, 2020 104.87 Mn
Dec 31, 2019 104.24 Mn
Sep 30, 2019 78.32 Mn
Jun 30, 2019 91.00 Mn
Mar 31, 2019 200.19
Dec 31, 2018 105.80 Mn
Sep 30, 2018 126.66
Jun 30, 2018 34.48 Mn
Mar 31, 2018 43,337.72
Dec 31, 2017 48.61 Mn
Dec 31, 2016 57.37 Mn
Sep 30, 2016 4,046.17
Dec 31, 2015 98.44 Mn
Mar 31, 2015 3.26 Mn
Dec 31, 2014 140.25 Mn
Sep 30, 2014 3.65 Mn
Dec 31, 2013 1.28 Mn