Growth Metrics

ProQR Therapeutics (PRQR) EBIAT (2013 - 2025)

ProQR Therapeutics recorded quarterly EBIAT of -$10.4 million in Q4 2025, up 19.3% quarter-over-quarter from -$12.9 million in Q3 2025, and down 4.42% year-over-year from -$10.9 million in Q4 2024.

ProQR Therapeutics' EBIAT history runs 13 years deep, the most recent figure standing at -$10.4 million for Q4 2025.

  • In Q4 2025, EBIAT fell 4.42% year-over-year to -$10.4 million; the TTM figure through Dec 2025 stood at -$47.6 million (down 58.44% YoY), while the FY2025 annual figure was -$49.1 million, down 65.51% from the prior year.
  • EBIAT came in at -$10.4 million for Q4 2025 at ProQR Therapeutics, up from -$12.9 million in the prior quarter.
  • In the past five years, EBIAT ranged from a high of $19.0 million in Q2 2021 to a low of -$23.5 million in Q3 2022.
  • A 5-year average of -$10.5 million and a median of -$10.5 million in 2025 frame the typical range for EBIAT.
  • On a YoY basis, EBIAT climbed as much as 318.15% in 2021 and fell as far as 85652.29% in 2021.
  • ProQR Therapeutics' EBIAT stood at -$20.9 million in 2021, then surged by 34.97% to -$13.6 million in 2022, then jumped by 56.52% to -$5.9 million in 2023, then sank by 68.55% to -$9.9 million in 2024, then decreased by 4.42% to -$10.4 million in 2025.
  • According to Business Quant data, EBIAT over the past three periods registered -$10.4 million, -$12.9 million, and -$13.8 million for Q4 2025, Q3 2025, and Q2 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIAT (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.99 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 30.90 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.03 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -3.63 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 727.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 205.99 Mn
10 ProQR Therapeutics 174.11 Mn 66.54 Mn - -10.38 Mn

Historic Data

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DateValue
Dec 31, 2025 -10.38 Mn
Sep 30, 2025 -12.87 Mn
Jun 30, 2025 -13.79 Mn
Mar 31, 2025 -10.60 Mn
Dec 31, 2024 -9.94 Mn
Sep 30, 2024 -8.90 Mn
Jun 30, 2024 -2.90 Mn
Mar 31, 2024 -8.32 Mn
Dec 31, 2023 -5.90 Mn
Sep 30, 2023 -5.90 Mn
Jun 30, 2023 -8.69 Mn
Mar 31, 2023 -9.50 Mn
Dec 31, 2022 -13.57 Mn
Sep 30, 2022 -23.50 Mn
Jun 30, 2022 -14.39 Mn
Mar 31, 2022 -15.84 Mn
Dec 31, 2021 -20.87 Mn
Sep 30, 2021 -17.77 Mn
Jun 30, 2021 18.97 Mn
Mar 31, 2021 -15.22 Mn
Dec 31, 2020 -15.77 Mn
Sep 30, 2020 15.41 Mn
Jun 30, 2020 4.54 Mn
Mar 31, 2020 -17,749.13
Dec 31, 2019 20.56 Mn
Sep 30, 2019 13.57 Mn
Jun 30, 2019 -13.18 Mn
Mar 31, 2019 16.19 Mn
Dec 31, 2018 -14.81 Mn
Sep 30, 2018 6.97 Mn
Jun 30, 2018 8.83 Mn
Mar 31, 2018 13,166.19
Dec 31, 2017 13.32 Mn
Sep 30, 2017 12,362.84
Jun 30, 2017 12.49 Mn
Mar 31, 2017 11,165.46
Dec 31, 2016 -9.52 Mn
Sep 30, 2016 -11.30 Mn
Jun 30, 2016 -12.01 Mn
Mar 31, 2016 -9.72 Mn
Dec 31, 2015 -22.82 Mn
Sep 30, 2015 -7,026.30
Jun 30, 2015 -7.13 Mn
Mar 31, 2015 265,510.64
Dec 31, 2014 -2.55 Mn
Sep 30, 2014 4.48 Mn
Mar 31, 2014 -2.63 Mn
Dec 31, 2013 -2.22 Mn
Sep 30, 2013 -1.16 Mn