ProQR Therapeutics (PRQR) EBT (2013 - 2025)

ProQR Therapeutics (PRQR) reported EBT of -$11.7 million for Q4 2025, down 27.33% on a YoY basis from -$16.1 million in Q4 2024, and up 9.32% sequentially from -$12.9 million in Q3 2025.

ProQR Therapeutics (PRQR) EBT (2013 - 2025) Analysis & Trends

ProQR Therapeutics (PRQR) has 13 years of EBT data on file, last reported at -$11.7 million in Q4 2025.

  • For the quarter ending Q4 2025, EBT fell 27.33% year-over-year to -$11.7 million; the trailing twelve-month figure through Dec 2025 stood at -$48.9 million (down 65.78% YoY), and the FY2025 full-year result was -$50.4 million, down 73.1% from the prior year.
  • EBT grew to -$11.7 million in Q4 2025, from -$12.9 million in the prior quarter.
  • In the past five years, EBT ranged from a high of -$3.1 million in Q2 2024 to a low of -$23.4 million in Q3 2022.
  • A 5-year average of -$12.5 million and a median of -$12.3 million in 2025 frame the typical range for EBT.
  • Across the five-year window, EBT jumped 74.62% in 2023 and sank 342.01% in 2025, its largest moves.
  • Tracing PRQR's EBT over 5 years: stood at -$20.8 million in 2021, then soared by 38.25% to -$12.9 million in 2022, then jumped by 43.15% to -$7.3 million in 2023, then decreased by 25.24% to -$9.2 million in 2024, then fell by 27.33% to -$11.7 million in 2025.
  • Business Quant data shows PRQR's EBT at -$11.7 million in Q4 2025, -$12.9 million in Q3 2025, and -$13.8 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 ProQR Therapeutics 182.23 Mn 138.42 Mn - -11.67 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -11.67 Mn
Sep 30, 2025 -12.87 Mn
Jun 30, 2025 -13.77 Mn
Mar 31, 2025 -10.60 Mn
Dec 31, 2024 -9.16 Mn
Sep 30, 2024 -8.90 Mn
Jun 30, 2024 -3.11 Mn
Mar 31, 2024 -8.32 Mn
Dec 31, 2023 -7.32 Mn
Sep 30, 2023 -5.94 Mn
Jun 30, 2023 -8.73 Mn
Mar 31, 2023 -9.50 Mn
Dec 31, 2022 -12.87 Mn
Sep 30, 2022 -23.43 Mn
Jun 30, 2022 -14.37 Mn
Mar 31, 2022 -15.84 Mn
Dec 31, 2021 -20.84 Mn
Sep 30, 2021 -17.73 Mn
Jun 30, 2021 -18.91 Mn
Mar 31, 2021 -15.21 Mn