ProQR Therapeutics (PRQR) Operating Expenses (2012 - 2026)

ProQR Therapeutics (PRQR) posted quarterly Operating Expenses of $17.8 million for Q1 2026, up 0.8% year-on-year from $17.7 million in Q1 2025, and down 85.17% on a QoQ basis from $120.4 million in Q4 2025.

ProQR Therapeutics (PRQR) Operating Expenses (2012 - 2026) Analysis & Trends

ProQR Therapeutics (PRQR) has reported Operating Expenses for 15 consecutive years, with $17.8 million the latest figure, recorded in Q1 2026.

  • Quarterly Operating Expenses rose 0.8% year-over-year to $17.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $103.6 million (up 16.25% YoY) and the FY2025 annual result came in at $68.0 million, up 19.55% from the prior year.
  • Operating Expenses eased to $17.8 million in Q1 2026 per PRQR's latest filing, from $120.4 million in the prior quarter.
  • Over the last five years, Operating Expenses for PRQR reached as high as $142.7 million in Q4 2022 and fell as low as -$23.6 million in Q3 2022.
  • A 5-year average of $17.9 million and a median of -$11.4 million in 2024 frame the typical range for Operating Expenses.
  • Annual changes were most pronounced in 2022 — Operating Expenses surged 805.41% — and 2025, when it slumped 61.26%.
  • Year by year, Operating Expenses stood at $142.7 million in 2022, then slumped by 43.94% to $80.0 million in 2023, then grew by 21.66% to $97.3 million in 2024, then advanced by 23.7% to $120.4 million in 2025, then tumbled by 85.17% to $17.8 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $17.8 million, $120.4 million, and -$16.2 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -28.01 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 1.10 Bn
4 NuCana 279.75 Bn 279.75 Bn - -3.78 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 2.89 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 445.22 Mn
10 ProQR Therapeutics 219.53 Mn 175.72 Mn - 17.85 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 17.85 Mn
Dec 31, 2025 120.36 Mn
Sep 30, 2025 -16.16 Mn
Jun 30, 2025 -18.46 Mn
Mar 31, 2025 17.70 Mn
Dec 31, 2024 97.31 Mn
Sep 30, 2024 -14.45 Mn
Jun 30, 2024 -11.45 Mn
Mar 31, 2024 -14.49 Mn
Dec 31, 2023 79.98 Mn
Sep 30, 2023 -9.97 Mn
Jun 30, 2023 -11.44 Mn
Mar 31, 2023 -11.48 Mn
Dec 31, 2022 142.66 Mn
Sep 30, 2022 -23.57 Mn
Jun 30, 2022 -19.19 Mn
Mar 31, 2022 -20.80 Mn
Dec 31, 2021 -20.22 Mn
Sep 30, 2021 -17.88 Mn
Jun 30, 2021 -15.77 Mn