ProQR Therapeutics (PRQR) Operating Expenses (2012 - 2026)

ProQR Therapeutics (PRQR) posted Operating Expenses of $18.4 million for Q1 2026, down 85.09% sequentially from $123.1 million in Q4 2025, and up 12.19% YoY from $16.4 million in Q1 2025.

ProQR Therapeutics (PRQR) Operating Expenses (2012 - 2026) Analysis & Trends

ProQR Therapeutics has reported Operating Expenses for 15 years, with the latest figure at $18.4 million in Q1 2026.

  • Quarterly Operating Expenses rose 12.19% year-over-year to $18.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $106.5 million (up 28.4% YoY) and the FY2025 annual result came in at $69.6 million, up 30.22% from the prior year.
  • Operating Expenses eased to $18.4 million in Q1 2026 per PRQR's latest filing, from $123.1 million in the prior quarter.
  • Over five years, Operating Expenses peaked at $127.9 million in Q4 2022 and troughed at -$20.9 million in Q3 2022.
  • A 5-year average of $17.0 million and a median of -$10.8 million in 2024 frame the typical range for Operating Expenses.
  • The sharpest annual moves came in 2022 and 2025: Operating Expenses surged 729.12% in 2022, then slumped 69.5% in 2025.
  • Over 5 years, Operating Expenses stood at $127.9 million in 2022, then tumbled by 40.88% to $75.6 million in 2023, then rose by 20.83% to $91.4 million in 2024, then soared by 34.75% to $123.1 million in 2025, then tumbled by 85.09% to $18.4 million in 2026.
  • According to Business Quant data, Operating Expenses over the past three periods registered $18.4 million, $123.1 million, and -$16.6 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 ProQR Therapeutics 206.80 Mn 111.86 Mn - 18.36 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 18.36 Mn
Dec 31, 2025 123.12 Mn
Sep 30, 2025 -16.60 Mn
Jun 30, 2025 -18.36 Mn
Mar 31, 2025 16.36 Mn
Dec 31, 2024 91.38 Mn
Sep 30, 2024 -13.94 Mn
Jun 30, 2024 -10.83 Mn
Mar 31, 2024 -13.83 Mn
Dec 31, 2023 75.62 Mn
Sep 30, 2023 -9.54 Mn
Jun 30, 2023 -10.95 Mn
Mar 31, 2023 -10.83 Mn
Dec 31, 2022 127.90 Mn
Sep 30, 2022 -20.88 Mn
Jun 30, 2022 -17.99 Mn
Mar 31, 2022 -20.51 Mn
Dec 31, 2021 -20.33 Mn
Sep 30, 2021 -18.53 Mn
Jun 30, 2021 -16.69 Mn