Growth Metrics

ProQR Therapeutics (PRQR) EBITDA (2016 - 2025)

ProQR Therapeutics' EBITDA history spans 5 years, with the latest figure at -$10.6 million for Q4 2025.

  • On a quarterly basis, EBITDA rose 1.7% to -$10.6 million in Q4 2025 year-over-year; TTM through Dec 2025 was -$23.2 million, a 243.95% decrease, with the full-year FY2025 number at -$47.4 million, down 60.16% from a year prior.
  • EBITDA hit -$10.6 million in Q4 2025 for ProQR Therapeutics, down from $12.9 million in the prior quarter.
  • Over the last five years, EBITDA for PRQR hit a ceiling of $20.7 million in Q4 2021 and a floor of -$22.9 million in Q3 2022.
  • Historically, EBITDA has averaged -$1.6 million across 5 years, with a median of -$7.4 million in 2023.
  • Biggest five-year swings in EBITDA: skyrocketed 205.78% in 2022 and later crashed 618.55% in 2025.
  • Tracing PRQR's EBITDA over 5 years: stood at $20.7 million in 2021, then tumbled by 161.46% to -$12.7 million in 2022, then surged by 46.95% to -$6.7 million in 2023, then plummeted by 59.73% to -$10.8 million in 2024, then grew by 1.7% to -$10.6 million in 2025.
  • Business Quant data shows EBITDA for PRQR at -$10.6 million in Q4 2025, $12.9 million in Q3 2025, and -$14.6 million in Q2 2025.