Growth Metrics

ProQR Therapeutics (PRQR) Enterprise Value (2013 - 2025)

ProQR Therapeutics recorded quarterly Enterprise Value of -$107.6 million in Q4 2025, up 32.62% quarter-over-quarter from -$159.7 million in Q4 2024, and up 32.62% year-over-year from -$81.1 million in Q4 2024.

ProQR Therapeutics' Enterprise Value history runs 13 years deep, the most recent figure standing at -$107.6 million for Q4 2025.

  • In Q4 2025, Enterprise Value rose 32.62% year-over-year to -$107.6 million; the TTM figure through Dec 2025 stood at -$107.6 million (up 32.62% YoY), while the FY2025 annual figure was -$107.6 million, up 32.62% from the prior year.
  • Enterprise Value came in at -$107.6 million for Q4 2025 at ProQR Therapeutics, up from -$159.7 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$91.5 million in Q1 2021 to a low of -$219.1 million in Q4 2021.
  • A 5-year average of -$146.6 million and a median of -$145.1 million in 2023 frame the typical range for Enterprise Value.
  • On a YoY basis, Enterprise Value climbed as much as 99.93% in 2021 and fell as far as 139.65% in 2021.
  • ProQR Therapeutics' Enterprise Value stood at -$219.1 million in 2021, then surged by 55.28% to -$98.0 million in 2022, then sank by 30.59% to -$128.0 million in 2023, then dropped by 24.77% to -$159.7 million in 2024, then soared by 32.62% to -$107.6 million in 2025.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$107.6 million, -$159.7 million, and -$128.0 million for Q4 2025, Q4 2024, and Q4 2023 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -2.32 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -7.25 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn -8.75 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -3.01 Bn
10 ProQR Therapeutics 174.11 Mn 66.54 Mn - -107.57 Mn

Historic Data

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DateValue
Dec 31, 2025 -107.57 Mn
Dec 31, 2024 -159.66 Mn
Dec 31, 2023 -127.96 Mn
Sep 30, 2023 -131.51 Mn
Jun 30, 2023 -140.40 Mn
Mar 31, 2023 -149.82 Mn
Dec 31, 2022 -97.98 Mn
Sep 30, 2022 -189.22 Mn
Jun 30, 2022 -167.13 Mn
Mar 31, 2022 -210.78 Mn
Dec 31, 2021 -219.09 Mn
Sep 30, 2021 -167.11 Mn
Jun 30, 2021 -93.28 Mn
Mar 31, 2021 -91.48 Mn
Dec 31, 2020 -91.42 Mn
Sep 30, 2020 -132.04 Mn
Jun 30, 2020 -123.31 Mn
Mar 31, 2020 -123.59 Bn
Dec 31, 2019 -123.92 Mn
Sep 30, 2019 -117.48 Mn
Jun 30, 2019 -118.63 Mn
Mar 31, 2019 -120.01 Mn
Dec 31, 2018 -120.51 Mn
Sep 30, 2018 -55.95 Mn
Jun 30, 2018 -57.40 Mn
Mar 31, 2018 -59,091.20 Bn
Dec 31, 2017 -56.63 Mn
Sep 30, 2017 -69,563.75 Bn
Jun 30, 2017 -65.09
Mar 31, 2017 -63,072.09
Dec 31, 2016 -63.92 Mn
Sep 30, 2016 -72,463.81
Dec 31, 2015 -103.98 Mn
Sep 30, 2015 -125.39 Bn
Mar 31, 2015 -128.59 Mn
Dec 31, 2014 -140.90 Mn
Sep 30, 2014 -50.69 Mn
Mar 31, 2014 -5.66 Mn
Dec 31, 2013 -5.62 Mn
Sep 30, 2013 -3.52 Mn