ProQR Therapeutics (PRQR) Operating Income (2017 - 2026)

ProQR Therapeutics (PRQR) posted Operating Income of -$16.0 million for Q1 2026, down 50.9% sequentially from -$10.6 million in Q4 2025, and down 40.45% YoY from -$26.8 million in Q1 2025.

ProQR Therapeutics (PRQR) Operating Income (2017 - 2026) Analysis & Trends

ProQR Therapeutics has reported Operating Income for 10 years, with the latest figure at -$16.0 million in Q1 2026.

  • Quarterly Operating Income fell 40.45% year-over-year to -$16.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$53.6 million (down 50.64% YoY) and the FY2025 annual result came in at -$50.6 million, down 55.31% from the prior year.
  • Operating Income slipped to -$16.0 million in Q1 2026 per PRQR's latest filing, from -$10.6 million in the prior quarter.
  • Over five years, Operating Income peaked at -$3.9 million in Q2 2024 and troughed at -$20.0 million in Q3 2022.
  • A 5-year average of -$11.8 million and a median of -$10.8 million in 2024 frame the typical range for Operating Income.
  • The sharpest annual moves came in 2023 and 2025: Operating Income surged 59.75% in 2023, then plunged 257.65% in 2025.
  • Over 5 years, Operating Income stood at -$12.7 million in 2022, then soared by 46.95% to -$6.7 million in 2023, then slumped by 59.73% to -$10.8 million in 2024, then advanced by 1.7% to -$10.6 million in 2025, then slumped by 50.9% to -$16.0 million in 2026.
  • According to Business Quant data, Operating Income over the past three periods registered -$16.0 million, -$10.6 million, and -$13.2 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 493.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 325.05 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -3,158.03
7 Royalty Pharma 33.72 Bn 35.84 Bn - 133.12 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 231.44 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.55 Mn
10 ProQR Therapeutics 206.80 Mn 111.86 Mn - -15.98 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -15.98 Mn
Dec 31, 2025 -10.59 Mn
Sep 30, 2025 -13.19 Mn
Jun 30, 2025 -13.87 Mn
Mar 31, 2025 -11.38 Mn
Dec 31, 2024 -10.77 Mn
Sep 30, 2024 -9.57 Mn
Jun 30, 2024 -3.88 Mn
Mar 31, 2024 -8.77 Mn
Dec 31, 2023 -6.74 Mn
Sep 30, 2023 -8.05 Mn
Jun 30, 2023 -9.59 Mn
Mar 31, 2023 -10.08 Mn
Dec 31, 2022 -12.71 Mn
Sep 30, 2022 -19.99 Mn
Jun 30, 2022 -16.89 Mn
Mar 31, 2022 -19.13 Mn
Dec 31, 2021 -19.82 Mn
Sep 30, 2021 -17.17 Mn
Jun 30, 2021 -15.90 Mn