Upstream Bio reported a net margin of -10,428.35% for the quarter ended Sep 2026. These financial ratios cover 13 quarters of results from Sep 2023 through Sep 2026, standardized by Business Quant from the company’s SEC filings.
| RatiosRatios | Sep2023 | Dec2023 | Mar2024 | Jun2024 | Sep2024 | Dec2024 | Mar2025 | Jun2025 | Sep2025 | Dec2025 | Mar2026 | Jun2026 | Sep2026 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Profitability | |||||||||||||
| Gross Margin | 45.16% | -177.65% | -258.98% | -350.24% | -276.15% | -967.24% | -272.18% | -1,148.80% | -380.95% | -425.87% | |||
| EBT Margin | -1,265.54% | -2,846.89% | -2,147.97% | -2,875.10% | -2,634.10% | -3,465.25% | -4,818.02% | -4,259.98% | -4,938.36% | -6,364.22% | -3,922.73% | -5,137.00% | -10,417.47% |
| EBIT Margin | -1,511.43% | -3,184.44% | -2,345.78% | -3,439.22% | -3,112.52% | -4,293.31% | -5,656.01% | -4,732.87% | -5,539.39% | -6,911.23% | -4,218.09% | -5,480.98% | -10,982.03% |
| EBITDA Margin | -3,236.44% | -2,441.09% | -3,660.59% | -3,204.45% | -4,174.06% | -5,954.95% | -4,833.51% | -5,555.20% | -6,695.51% | -4,286.27% | -5,479.56% | -11,076.71% | |
| Operating Margin | -1,511.43% | -3,184.44% | -2,345.78% | -3,439.22% | -3,112.52% | -4,293.31% | -5,656.01% | -4,732.87% | -5,539.39% | -6,911.23% | -4,218.09% | -5,480.98% | -10,982.03% |
| Net Margin | -1,006.92% | -3,329.78% | -2,189.06% | -3,835.69% | -3,465.07% | -3,554.65% | -4,818.02% | -4,265.31% | -4,941.14% | -6,356.14% | -3,925.63% | -5,136.09% | -10,428.35% |
| FCF Margin | -3,580.00% | -2,744.06% | -1,575.69% | -2,300.16% | -3,229.53% | -7,272.97% | -4,187.73% | -3,265.59% | -4,593.56% | -4,627.85% | -4,608.15% | -13,729.11% | |
| Efficiency | |||||||||||||
| Assets AverageAssets Avg. | 357.21M | 468.94M | 438.35M | 405.86M | 372.48M | 335.91M | 299.61M | 263.58M | |||||
| Equity AverageEquity Avg. | -117.67M | -128.27M | -140.01M | -153.46M | 154.77M | 457.73M | 427.18M | 393.66M | 359.18M | 321.88M | 287.48M | 252.47M | |
| Asset Utilization RatioAsset Util. | 0.01 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 | |||||
| Valuation | |||||||||||||
| Price to SalesP/S | 94.91 | 142.98 | 216.93 | 362.89 | 515.96 | 147.44 | 120.02 | 100.65 | |||||
| Price to BookP/B | 0.48 | 0.74 | 1.45 | 2.68 | 4.33 | 1.61 | 1.40 | 1.23 | |||||
| Enterprise Value | -245.51M | -103.10M | 197.12M | 643.30M | 1,131.05M | 195.20M | 117.71M | 81.49M | |||||
| Market Capitalization | 224.94M | 328.28M | 590.70M | 1,015.73M | 1,472.55M | 489.78M | 379.02M | 288.86M | |||||
| Return Ratios | |||||||||||||
| Return on Sales [ROS]ROS | -1,511.43% | -3,184.44% | -2,345.78% | -3,439.22% | -3,112.52% | -4,293.31% | -5,656.01% | -4,732.87% | -5,539.39% | -6,911.23% | -4,218.09% | -5,480.98% | -10,982.03% |
| Return on Capital Employed [ROCE]ROCE | -22.44% | -20.63% | -28.44% | -35.67% | -44.66% | -53.36% | -58.69% | -69.76% | |||||
| Return on Assets [ROA]ROA | -17.60% | -16.80% | -23.76% | -30.08% | -38.36% | -46.75% | -52.36% | -62.51% | |||||
| Return on Equity [ROE]ROE | -40.61% | -17.21% | -24.38% | -31.01% | -39.78% | -48.79% | -54.57% | -65.26% |
Pull Upstream Bio's standardized financial statements into your own models, spreadsheets and apps with the Business Quant Financial Statements API. The request below follows the statement, frequency and period selected above. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/statements?ticker=UPB&statement=Ratios&frequency=Quarter&period=all&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/statements"
params = {"ticker": "UPB", "statement": "Ratios", "frequency": "Quarter", "period": "all", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/statements?ticker=UPB&statement=Ratios&frequency=Quarter&period=all&api_key=YOUR_API_KEY");
const data = await res.json();