Enanta Pharmaceuticals (ENTA) EBITDA Margin (2012 - 2026)

Enanta Pharmaceuticals (ENTA) posted EBITDA Margin of 69.07% for Q1 2026, down 14.26% on a QoQ basis from 60.45% in Q4 2025, and up 9525.0% year-over-year from 0.72% in Q1 2025.

Enanta Pharmaceuticals (ENTA) EBITDA Margin (2012 - 2026) Analysis & Trends

Enanta Pharmaceuticals' EBITDA Margin history runs 15 years deep, the most recent figure standing at 69.07% for Q1 2026.

  • Quarterly EBITDA Margin rose 9525.0% year-over-year to 69.07% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 87.24% (up 7116.0% YoY) and the FY2025 annual result came in at 130.65%, up 4927.0% from the prior year.
  • EBITDA Margin was 69.07% for Q1 2026 at Enanta Pharmaceuticals, down from 60.45% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 60.45% in Q4 2025 and bottomed at 221.7% in Q1 2023.
  • A 5-year average of 151.2% and a median of 163.9% in 2023 frame the typical range for EBITDA Margin.
  • Annual changes were most pronounced in 2023 — EBITDA Margin slumped 6652 bps — and 2026, when it surged 9525 bps.
  • Enanta Pharmaceuticals' EBITDA Margin stood at 127.25% in 2022, then plunged by 52 bps to 193.78% in 2023, then advanced by 28 bps to 138.82% in 2024, then soared by 56 bps to 60.45% in 2025, then declined by 14 bps to 69.07% in 2026.
  • Business Quant data shows ENTA's EBITDA Margin at 69.07% in Q1 2026, 60.45% in Q4 2025, and 121.56% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 16.51%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 17.83%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 30.35%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Enanta Pharmaceuticals 369.97 Mn 206.20 Mn - -69.07%

Historic Data

Download Data
DateValue
Mar 31, 2026 -69.07%
Dec 31, 2025 -60.45%
Sep 30, 2025 -121.56%
Jun 30, 2025 -103.16%
Mar 31, 2025 -164.32%
Dec 31, 2024 -138.82%
Sep 30, 2024 -204.38%
Jun 30, 2024 -134.58%
Mar 31, 2024 -192.13%
Dec 31, 2023 -193.78%
Sep 30, 2023 -163.90%
Jun 30, 2023 -194.33%
Mar 31, 2023 -221.70%
Dec 31, 2022 -127.25%
Sep 30, 2022 -133.13%
Jun 30, 2022 -167.05%
Mar 31, 2022 -180.85%
Dec 31, 2021 -109.99%
Sep 30, 2021 -143.06%
Jun 30, 2021 -156.53%