Enanta Pharmaceuticals (ENTA) EBITDA Margin (2012 - 2026)

Enanta Pharmaceuticals' (ENTA) quarterly EBITDA Margin came in at 69.07% in Q1 2026, up 9525.0% YoY from 0.72% in Q1 2025, and down 14.26% on a QoQ basis from 60.45% in Q4 2025.

Enanta Pharmaceuticals (ENTA) EBITDA Margin (2012 - 2026) Analysis & Trends

Enanta Pharmaceuticals (ENTA) has 15 years of EBITDA Margin data on file, last reported at 69.07% in Q1 2026.

  • Quarterly EBITDA Margin rose 9525.0% year-over-year to 69.07% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 87.24% (up 7116.0% YoY) and the FY2025 annual result came in at 130.65%, up 4927.0% from the prior year.
  • EBITDA Margin retreated to 69.07% in Q1 2026, from 60.45% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 60.45% in Q4 2025 to a low of 221.7% in Q1 2023.
  • A 5-year average of 151.2% and a median of 163.9% in 2023 frame the typical range for EBITDA Margin.
  • Annual changes were most pronounced in 2023 — EBITDA Margin tumbled 6652 bps — and 2026, when it surged 9525 bps.
  • Tracing ENTA's EBITDA Margin over 5 years: stood at 127.25% in 2022, then slumped by 52 bps to 193.78% in 2023, then rose by 28 bps to 138.82% in 2024, then jumped by 56 bps to 60.45% in 2025, then slipped by 14 bps to 69.07% in 2026.
  • The last three EBITDA Margin figures came in at 69.07% (Q1 2026), 60.45% (Q4 2025), and 121.56% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.15%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 31.68%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 19.06%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -77,569,866.34%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 19.75%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 17.93%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -0.36%
10 Enanta Pharmaceuticals 383.29 Mn 193.78 Mn - -120.04%

Historic Data

Download Data
DateValue
Jun 30, 2026 -120.04%
Mar 31, 2026 -69.07%
Dec 31, 2025 -60.45%
Sep 30, 2025 -121.56%
Jun 30, 2025 -103.16%
Mar 31, 2025 -164.32%
Dec 31, 2024 -138.82%
Sep 30, 2024 -204.38%
Jun 30, 2024 -134.58%
Mar 31, 2024 -192.13%
Dec 31, 2023 -193.78%
Sep 30, 2023 -163.90%
Jun 30, 2023 -194.33%
Mar 31, 2023 -221.70%
Dec 31, 2022 -127.25%
Sep 30, 2022 -133.13%
Jun 30, 2022 -167.05%
Mar 31, 2022 -180.85%
Dec 31, 2021 -109.99%
Sep 30, 2021 -143.06%