Enanta Pharmaceuticals Inc (ENTA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

28,748,000Shares Outstanding

26,622,118Shares held by institutions

$375,105,643Value of institutional holdings

92.61%Institutional ownership %

35.28%Shares Changed QoQ

127No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Enanta Pharmaceuticals Inc (NASDAQ:ENTA) has 127 institutional investors with active 13F positions as of December 2025.

These investors collectively held 91.8% of Enanta Pharmaceuticals's outstanding shares in December 2025, down from 99.7% in September 2025.
They increased total shares held in Enanta Pharmaceuticals by 34.62% from the prior quarter, while the number of investors in ENTA increased 18.69% year over year.
During the quarter, 78 of these 127 funds increased positions in ENTA, 29 reduced exposure, and 20 held steady.
Institutional investors collectively held 26.4Mn shares in Enanta Pharmaceuticals as of December 2025, up by 6.79Mn shares quarter on quarter, and up 3.73Mn shares year over year.
Janus Henderson Group Plc holds the largest position in ENTA at 3.73Mn shares as of December 31, 2025, or 12.97% of shares outstanding.
Leading buyers of Enanta Pharmaceuticals shares for the quarter ending December 2025 were Deep Track Capital, LP (1.96Mn), Janus Henderson Group Plc (1.78Mn), BlackRock, Inc. (1.24Mn), Krensavage Asset Management, LLC (651.95K), Hillsdale Investment Management Inc. (422.3K).
The largest sellers of Enanta Pharmaceuticals for the quarter ending December 2025 were FARALLON CAPITAL MANAGEMENT LLC (1.47Mn), MILLENNIUM MANAGEMENT LLC (277.66K), Stonepine Capital Management, LLC (205.0K), Jpmorgan Chase & Co (134.67K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (106.84K).
Per Business Quant, the top 10 investors in ENTA for the quarter ending December 2025 include Janus Henderson Group Plc (3.73Mn), BlackRock, Inc. (3.08Mn), FARALLON CAPITAL MANAGEMENT LLC (2.77Mn), Krensavage Asset Management, LLC (2.77Mn), VANGUARD GROUP INC (2.3Mn), Deep Track Capital, LP (1.96Mn), ACADIAN ASSET MANAGEMENT LLC (885.13K), MILLENNIUM MANAGEMENT LLC (670.43K), GEODE CAPITAL MANAGEMENT, LLC (645.79K), RENAISSANCE TECHNOLOGIES LLC (642.2K).

127 Institutional Holders

26,622,118 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
Janus Henderson Group Plc	31 Dec, 2025	3,729,659	1,782,745	91.57%	$58,760,778.00
BlackRock, Inc.	31 Dec, 2025	3,076,282	1,243,302	67.83%	$48,512,966.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	2,772,262	-1,472,262	-34.69%	$43,718,572.00
Krensavage Asset Management, LLC	31 Dec, 2025	2,766,390	651,946	30.83%	$43,626.00
VANGUARD GROUP INC	31 Dec, 2025	2,301,794	362,965	18.72%	$36,299,291.00
Deep Track Capital, LP	31 Dec, 2025	1,956,867	1,956,867	0.00%	$30,859,793.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	885,126	18,089	2.09%	$13,946.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	670,428	-277,656	-29.29%	$10,572,650.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	645,791	152,597	30.94%	$10,186,549.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	642,200	162,600	33.90%	$10,127,494.00
State Street Corp	31 Dec, 2025	523,715	51,723	10.96%	$8,258,986.00
Point72 Asset Management, L.P.	31 Dec, 2025	438,939	138,939	46.31%	$6,922,068.00
Goldman Sachs Group Inc	31 Dec, 2025	437,632	271,199	162.95%	$6,901,456.00
Hillsdale Investment Management Inc.	31 Dec, 2025	422,300	422,300	0.00%	$6,659,671.00
Spruce Street Capital LP	31 Dec, 2025	389,687	389,687	0.00%	$6,145,364.00
MARSHALL WACE, LLP	31 Dec, 2025	385,276	109,887	39.90%	$6,075,802.00
Morgan Stanley	31 Dec, 2025	339,918	57,287	20.27%	$5,360,518.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	285,448	224,726	370.09%	$4,501,515.00
Invesco Ltd.	31 Dec, 2025	249,998	190,300	318.77%	$3,942,468.00
AQR CAPITAL MANAGEMENT LLC	31 Dec, 2025	234,835	7,990	3.52%	$3,703,349.00

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