Enanta Pharmaceuticals Inc (ENTA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

28,423,810Shares Outstanding

158,634Shares held by institutions

$2,198,667Value of institutional holdings

82.07%Institutional ownership %

51.79%Shares Changed QoQ

122No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

The institutional landscape for Enanta Pharmaceuticals Inc (NASDAQ:ENTA) includes 122 filers as of the latest reporting cycle ending December 2025.

The collective stake of institutional investors in Enanta Pharmaceuticals moved to 82.1% in December 2025, a shift down from the 90.2% reported for September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 51.79%, with a year-over-year an increase of 14.02% in the count of filers.
Among the 122 institutional holders of Enanta Pharmaceuticals, 75 added to their stakes while 27 trimmed their positions and 20 held steady.
The total number of shares held by institutions in Enanta Pharmaceuticals increased to 23.33Mn as of December 2025, a net change of up by 7.96Mn shares quarter on quarter, and up 1.92Mn shares year over year.
JANUS HENDERSON GROUP PLC's holding of 3.73Mn shares as of December 31, 2025 makes it the primary institutional investor in Enanta Pharmaceuticals, owning 13.12% of the stock.
Among the most significant buyers of Enanta Pharmaceuticals during December 2025 were Deep Track Capital, LP (1.96Mn), JANUS HENDERSON GROUP PLC (1.78Mn), BlackRock, Inc. (1.24Mn), FARALLON CAPITAL MANAGEMENT LLC (650.00K), Hillsdale Investment Management Inc. (422.30K).
Leading sellers of Enanta Pharmaceuticals stock in December 2025 included MILLENNIUM MANAGEMENT LLC (484.66K), Stonepine Capital Management, LLC (205.00K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (106.84K), Nuveen, LLC (78.70K), DIMENSIONAL FUND ADVISORS LP (58.45K).
The top 10 institutional holders of Enanta Pharmaceuticals for the quarter ending December 2025 included JANUS HENDERSON GROUP PLC (3.73Mn), BlackRock, Inc. (3.08Mn), FARALLON CAPITAL MANAGEMENT LLC (2.77Mn), VANGUARD GROUP INC (2.30Mn), Deep Track Capital, LP (1.96Mn), ACADIAN ASSET MANAGEMENT LLC (885.13K), MILLENNIUM MANAGEMENT LLC (670.43K), GEODE CAPITAL MANAGEMENT, LLC (645.79K), RENAISSANCE TECHNOLOGIES LLC (642.20K), STATE STREET CORP (523.72K).

122 Institutional Holders

158,634 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
JANUS HENDERSON GROUP PLC	31 Dec, 2025	3,729,659	1,782,745	91.57%	$58,760,778.00
BlackRock, Inc.	31 Dec, 2025	3,076,282	1,243,302	67.83%	$48,512,966.00
FARALLON CAPITAL MANAGEMENT LLC	31 Dec, 2025	2,772,262	650,000	30.63%	$43,718,572.00
VANGUARD GROUP INC	31 Dec, 2025	2,301,794	362,965	18.72%	$36,299,291.00
Deep Track Capital, LP	31 Dec, 2025	1,956,867	1,956,867	0.00%	$30,859,793.00
ACADIAN ASSET MANAGEMENT LLC	31 Dec, 2025	885,126	18,089	2.09%	$13,946.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	670,428	-484,656	-41.96%	$10,572,650.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	645,791	152,597	30.94%	$10,186,549.00
RENAISSANCE TECHNOLOGIES LLC	31 Dec, 2025	642,200	162,600	33.90%	$10,127,494.00
STATE STREET CORP	31 Dec, 2025	523,715	51,723	10.96%	$8,258,986.00
Point72 Asset Management, L.P.	31 Dec, 2025	438,939	138,939	46.31%	$6,922,068.00
Hillsdale Investment Management Inc.	31 Dec, 2025	422,300	422,300	0.00%	$6,659,671.00
Spruce Street Capital LP	31 Dec, 2025	389,687	389,687	0.00%	$6,145,364.00
MARSHALL WACE, LLP	31 Dec, 2025	385,276	109,887	39.90%	$6,075,802.00
MORGAN STANLEY	31 Dec, 2025	339,918	57,287	20.27%	$5,360,518.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	285,448	224,726	370.09%	$4,501,515.00
AQR CAPITAL MANAGEMENT LLC	31 Dec, 2025	234,835	7,990	3.52%	$3,703,349.00
NORTHERN TRUST CORP	31 Dec, 2025	229,889	33,993	17.35%	$3,625,349.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	218,816	52,383	31.47%	$3,450,728.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	218,636	52,089	31.28%	$3,447,890.00

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