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Castle Biosciences (CSTL) Operating Margin: 2018-2025

Historic Operating Margin for Castle Biosciences (CSTL) over the last 8 years, with Sep 2025 value amounting to -8.19%.

  • Castle Biosciences' Operating Margin fell 1411.00% to -8.19% in Q3 2025 from the same period last year, while for Sep 2025 it was -10.17%, marking a year-over-year decrease of 984.00%. This contributed to the annual value of 2.61% for FY2024, which is 3354.00% up from last year.
  • According to the latest figures from Q3 2025, Castle Biosciences' Operating Margin is -8.19%, which was down 66.12% from -4.93% recorded in Q2 2025.
  • In the past 5 years, Castle Biosciences' Operating Margin registered a high of 5.92% during Q3 2024, and its lowest value of -91.30% during Q1 2022.
  • For the 3-year period, Castle Biosciences' Operating Margin averaged around -16.13%, with its median value being -8.19% (2025).
  • Per our database at Business Quant, Castle Biosciences' Operating Margin plummeted by 7,252bps in 2022 and then surged by 6,749bps in 2024.
  • Over the past 5 years, Castle Biosciences' Operating Margin (Quarterly) stood at -60.59% in 2021, then surged by 103bps to -59.55% in 2022, then surged by 5,100bps to -8.56% in 2023, then skyrocketed by 1,325bps to 4.69% in 2024, then plummeted by 1,411bps to -8.19% in 2025.
  • Its last three reported values are -8.19% in Q3 2025, -4.93% for Q2 2025, and -31.74% during Q1 2025.