Growth Metrics

Castle Biosciences (CSTL) Operating Margin (2018 - 2025)

Castle Biosciences' Operating Margin history spans 7 years, with the latest figure at 4.4% for Q4 2025.

  • For Q4 2025, Operating Margin fell 909.0% year-over-year to 4.4%; the TTM value through Dec 2025 reached 12.44%, down 1505.0%, while the annual FY2025 figure was 12.44%, 1505.0% down from the prior year.
  • Operating Margin for Q4 2025 was 4.4% at Castle Biosciences, up from 8.19% in the prior quarter.
  • Across five years, Operating Margin topped out at 5.92% in Q3 2024 and bottomed at 91.3% in Q1 2022.
  • The 5-year median for Operating Margin is 17.23% (2023), against an average of 28.53%.
  • The largest annual shift saw Operating Margin crashed -7252bps in 2022 before it soared 6749bps in 2024.
  • A 5-year view of Operating Margin shows it stood at 60.59% in 2021, then rose by 2bps to 59.55% in 2022, then soared by 86bps to 8.56% in 2023, then skyrocketed by 155bps to 4.69% in 2024, then tumbled by -194bps to 4.4% in 2025.
  • Per Business Quant, the three most recent readings for CSTL's Operating Margin are 4.4% (Q4 2025), 8.19% (Q3 2025), and 4.93% (Q2 2025).