Castle Biosciences (CSTL) EBT Margin (2018 - 2026)
Castle Biosciences' (CSTL) quarterly EBT Margin came in at 1.63% in Q2 2026, down 147.0% year-over-year from 3.47% in Q2 2025, and up 90.52% quarter-over-quarter from 17.22% in Q1 2026.
Powered by 
Analysis
Castle Biosciences (CSTL) EBT Margin (2018 - 2026) Analysis & Trends
Castle Biosciences has disclosed EBT Margin across 9 years of filings, most recently posting 1.63% for Q2 2026.
- In Q2 2026, EBT Margin fell 147.0% year-over-year to 1.63%; the TTM figure through Jun 2026 stood at 5.37% (down 242.0% YoY), while the FY2025 annual figure was 8.57%, down 1507.0% from the prior year.
- EBT Margin came in at 1.63% for Q2 2026 at Castle Biosciences, up from 17.22% in the prior quarter.
- In the past five years, EBT Margin ranged from a high of 9.65% in Q3 2024 to a low of 91.2% in Q1 2022.
- Average EBT Margin over 5 years is 19.99%, with a median of 7.1% recorded in 2023.
- Year-over-year, EBT Margin sank 7244 bps in 2022 and surged 6603 bps in 2024.
- Over 5 years, EBT Margin stood at 53.63% in 2022, then surged by 93 bps to 3.84% in 2023, then surged by 338 bps to 9.14% in 2024, then tumbled by 134 bps to 3.12% in 2025, then surged by 48 bps to 1.63% in 2026.
- Per Business Quant data, the three most recent EBT Margin figures were 1.63% in Q2 2026, 17.22% in Q1 2026, and 3.12% in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Natera | 53.05 Bn | 51.95 Bn | 486.15 Mn | -8.93% |
| 2 | Quest Diagnostics | 27.19 Bn | 26.87 Bn | 1.03 Bn | 13.54% |
| 3 | Labcorp Holdings | 25.93 Bn | 25.81 Bn | 1.11 Bn | 10.36% |
| 4 | Guardant Health | 23.97 Bn | 22.91 Bn | 219.03 Mn | -35.81% |
| 5 | Tempus AI | 13.64 Bn | 12.82 Bn | 274.25 Mn | 2.30% |
| 6 | Caris Life Sciences | 8.47 Bn | 7.68 Bn | 182.38 Mn | -0.23% |
| 7 | Sotera Health | 5.35 Bn | 4.99 Bn | 177.96 Mn | 24.29% |
| 8 | BillionToOne | 4.96 Bn | 4.41 Bn | 77.11 Mn | 6.87% |
| 9 | Adaptive Biotechnologies | 4.55 Bn | 4.21 Bn | 51.39 Mn | -22.65% |
| 10 | Castle Biosciences | 1.08 Bn | 811.36 Mn | 79.85 Mn | -1.63% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -1.63% |
| Mar 31, 2026 | -17.22% |
| Dec 31, 2025 | -3.12% |
| Sep 30, 2025 | -0.46% |
| Jun 30, 2025 | -0.17% |
| Mar 31, 2025 | -29.86% |
| Dec 31, 2024 | 9.14% |
| Sep 30, 2024 | 9.65% |
| Jun 30, 2024 | 9.06% |
| Mar 31, 2024 | -3.41% |
| Dec 31, 2023 | -3.84% |
| Sep 30, 2023 | -11.18% |
| Jun 30, 2023 | -37.42% |
| Mar 31, 2023 | -69.44% |
| Dec 31, 2022 | -53.63% |
| Sep 30, 2022 | -54.71% |
| Jun 30, 2022 | -10.35% |
| Mar 31, 2022 | -91.20% |
| Dec 31, 2021 | -60.53% |
| Sep 30, 2021 | -50.23% |
API Access
Castle Biosciences EBT Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebt-margin&ticker=CSTL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebt-margin", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebt-margin&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();