Castle Biosciences (CSTL) Gross Profit (2018 - 2026)

Castle Biosciences' (CSTL) quarterly Gross Profit came in at $63.1 million in Q1 2026, down 11.81% year-on-year from $71.6 million in Q1 2025, and down 8.08% quarter-over-quarter from $68.7 million in Q4 2025.

Castle Biosciences (CSTL) Gross Profit (2018 - 2026) Analysis & Trends

Castle Biosciences has disclosed Gross Profit across 9 years of filings, most recently posting $63.1 million for Q1 2026.

  • Gross Profit for Q1 2026 came in at $63.1 million, down 11.81% year-over-year; the trailing twelve-month figure through Mar 2026 was $264.7 million (down 6.91% YoY), and the FY2025 annual result was $273.2 million, changed 0.49% from the prior year.
  • Gross Profit came in at $63.1 million for Q1 2026 at Castle Biosciences, down from $68.7 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $72.5 million in Q2 2024 to a low of $20.9 million in Q1 2022.
  • The 5-year median for Gross Profit is $59.1 million (2024), against an average of $52.2 million.
  • Across the five-year window, Gross Profit jumped 86.33% in 2023 and retreated 11.81% in 2026, its largest moves.
  • Castle Biosciences' Gross Profit stood at $28.8 million in 2022, then soared by 86.33% to $53.7 million in 2023, then surged by 30.6% to $70.1 million in 2024, then declined by 2.04% to $68.7 million in 2025, then fell by 8.08% to $63.1 million in 2026.
  • The last three Gross Profit figures came in at $63.1 million (Q1 2026), $68.7 million (Q4 2025), and $64.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn
10 Castle Biosciences 601.82 Mn 340.09 Mn 63.15 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 63.15 Mn
Mar 31, 2026 63.15 Mn
Dec 31, 2025 68.70 Mn
Dec 31, 2025 68.70 Mn
Sep 30, 2025 64.34 Mn
Sep 30, 2025 64.34 Mn
Jun 30, 2025 68.56 Mn
Jun 30, 2025 68.56 Mn
Mar 31, 2025 71.61 Mn
Mar 31, 2025 71.61 Mn
Dec 31, 2024 70.13 Mn
Dec 31, 2024 70.13 Mn
Sep 30, 2024 70.17 Mn
Sep 30, 2024 70.17 Mn
Jun 30, 2024 72.48 Mn
Jun 30, 2024 72.48 Mn
Mar 31, 2024 59.08 Mn
Mar 31, 2024 59.08 Mn
Dec 31, 2023 53.70 Mn
Dec 31, 2023 53.70 Mn