Castle Biosciences CSTL
NASDAQ CSTL
$35.35 +0.36 (+1.03%)
As of: Sep 22, 2026 · 10:04 AM EDT

Castle Biosciences (CSTL) Gross Profit (2018 - 2026)

Castle Biosciences' (CSTL) quarterly Gross Profit came in at $79.8 million in Q2 2026, up 16.46% year-over-year from $68.6 million in Q2 2025, and up 26.45% quarter-over-quarter from $63.1 million in Q1 2026.

Analysis

Castle Biosciences (CSTL) Gross Profit (2018 - 2026) Analysis & Trends

Castle Biosciences has disclosed Gross Profit across 9 years of filings, most recently posting $79.8 million for Q2 2026.

  • In Q2 2026, Gross Profit rose 16.46% year-over-year to $79.8 million; the TTM figure through Jun 2026 stood at $276.0 million (down 1.58% YoY), while the FY2025 annual figure was $273.2 million, changed 0.49% from the prior year.
  • Gross Profit came in at $79.8 million for Q2 2026 at Castle Biosciences, up from $63.1 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $79.8 million in Q2 2026 to a low of $20.9 million in Q1 2022.
  • Average Gross Profit over 5 years is $53.8 million, with a median of $61.1 million recorded in 2024.
  • Year-over-year, Gross Profit surged 86.33% in 2023 and decreased 11.81% in 2026.
  • Over 5 years, Gross Profit stood at $28.8 million in 2022, then soared by 86.33% to $53.7 million in 2023, then surged by 30.6% to $70.1 million in 2024, then declined by 2.04% to $68.7 million in 2025, then climbed by 16.23% to $79.8 million in 2026.
  • Per Business Quant data, the three most recent Gross Profit figures were $79.8 million in Q2 2026, $63.1 million in Q1 2026, and $68.7 million in Q4 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Natera 53.05 Bn 51.95 Bn 486.15 Mn
2 Quest Diagnostics 27.19 Bn 26.87 Bn 1.03 Bn
3 Labcorp Holdings 25.93 Bn 25.81 Bn 1.11 Bn
4 Guardant Health 23.97 Bn 22.91 Bn 219.03 Mn
5 Tempus AI 13.64 Bn 12.82 Bn 274.25 Mn
6 Caris Life Sciences 8.47 Bn 7.68 Bn 182.38 Mn
7 Sotera Health 5.35 Bn 4.99 Bn 177.96 Mn
8 BillionToOne 4.96 Bn 4.41 Bn 77.11 Mn
9 Adaptive Biotechnologies 4.55 Bn 4.21 Bn 51.39 Mn
10 Castle Biosciences 1.08 Bn 811.36 Mn 79.85 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 79.85 Mn
Mar 31, 2026 63.15 Mn
Dec 31, 2025 68.70 Mn
Sep 30, 2025 64.34 Mn
Jun 30, 2025 68.56 Mn
Mar 31, 2025 71.61 Mn
Dec 31, 2024 70.13 Mn
Sep 30, 2024 70.17 Mn
Jun 30, 2024 72.48 Mn
Mar 31, 2024 59.08 Mn
Dec 31, 2023 53.70 Mn
Sep 30, 2023 50.17 Mn
Jun 30, 2023 39.08 Mn
Mar 31, 2023 31.86 Mn
Dec 31, 2022 28.82 Mn
Sep 30, 2022 28.15 Mn
Jun 30, 2022 27.15 Mn
Mar 31, 2022 20.91 Mn
Dec 31, 2021 20.44 Mn
Sep 30, 2021 18.98 Mn
API Access

Castle Biosciences Gross Profit API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=gross-profit&ticker=CSTL&period=max&api_key=YOUR_API_KEY