Castle Biosciences (CSTL) Gross Profit (2018 - 2026)

Castle Biosciences (CSTL) posted Gross Profit of $63.1 million for Q1 2026, down 8.08% sequentially from $68.7 million in Q4 2025, and down 11.81% YoY from $71.6 million in Q1 2025.

Castle Biosciences (CSTL) Gross Profit (2018 - 2026) Analysis & Trends

Castle Biosciences (CSTL) has 9 years of Gross Profit data on file, last reported at $63.1 million in Q1 2026.

  • Quarterly Gross Profit fell 11.81% year-over-year to $63.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $264.7 million (down 6.91% YoY) and the FY2025 annual result came in at $273.2 million, changed 0.49% from the prior year.
  • Gross Profit retreated to $63.1 million in Q1 2026 per CSTL's latest filing, from $68.7 million in the prior quarter.
  • The five-year high for Gross Profit was $72.5 million in Q2 2024, with the low at $20.9 million in Q1 2022.
  • Average Gross Profit over 5 years is $52.2 million, with a median of $59.1 million recorded in 2024.
  • Year-over-year, Gross Profit surged 86.33% in 2023 and declined 11.81% in 2026.
  • Castle Biosciences' Gross Profit stood at $28.8 million in 2022, then soared by 86.33% to $53.7 million in 2023, then surged by 30.6% to $70.1 million in 2024, then decreased by 2.04% to $68.7 million in 2025, then slipped by 8.08% to $63.1 million in 2026.
  • Business Quant data shows CSTL's Gross Profit at $63.1 million in Q1 2026, $68.7 million in Q4 2025, and $64.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn
10 Castle Biosciences 738.56 Mn 476.84 Mn 63.15 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 63.15 Mn
Mar 31, 2026 63.15 Mn
Dec 31, 2025 68.70 Mn
Dec 31, 2025 68.70 Mn
Sep 30, 2025 64.34 Mn
Sep 30, 2025 64.34 Mn
Jun 30, 2025 68.56 Mn
Jun 30, 2025 68.56 Mn
Mar 31, 2025 71.61 Mn
Mar 31, 2025 71.61 Mn
Dec 31, 2024 70.13 Mn
Dec 31, 2024 70.13 Mn
Sep 30, 2024 70.17 Mn
Sep 30, 2024 70.17 Mn
Jun 30, 2024 72.48 Mn
Jun 30, 2024 72.48 Mn
Mar 31, 2024 59.08 Mn
Mar 31, 2024 59.08 Mn
Dec 31, 2023 53.70 Mn
Dec 31, 2023 53.70 Mn