Growth Metrics

Castle Biosciences (CSTL) Gross Margin (2018 - 2025)

Castle Biosciences' Gross Margin history spans 7 years, with the latest figure at 78.95% for Q4 2025.

  • For Q4 2025, Gross Margin fell 230.0% year-over-year to 78.95%; the TTM value through Dec 2025 reached 79.37%, down 250.0%, while the annual FY2025 figure was 79.37%, 250.0% down from the prior year.
  • Gross Margin for Q4 2025 was 78.95% at Castle Biosciences, up from 77.48% in the prior quarter.
  • Across five years, Gross Margin topped out at 100.0% in Q3 2021 and bottomed at 75.17% in Q4 2022.
  • The 5-year median for Gross Margin is 81.09% (2023), against an average of 81.02%.
  • The largest annual shift saw Gross Margin soared 1626bps in 2021 before it tumbled -2394bps in 2022.
  • A 5-year view of Gross Margin shows it stood at 81.64% in 2021, then decreased by -8bps to 75.17% in 2022, then increased by 8bps to 81.21% in 2023, then rose by 0bps to 81.25% in 2024, then dropped by -3bps to 78.95% in 2025.
  • Per Business Quant, the three most recent readings for CSTL's Gross Margin are 78.95% (Q4 2025), 77.48% (Q3 2025), and 79.55% (Q2 2025).