Castle Biosciences (CSTL) Gross Margin (2018 - 2026)
Castle Biosciences (CSTL) posted Gross Margin of 76.75% for Q3 2026, down 0.72 percentage points from 77.48% a year earlier and down 0.36 percentage points from the prior quarter.
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Analysis
Castle Biosciences (CSTL) Gross Margin (2018 - 2026) Analysis & Trends
For the trailing twelve months through Sep 30, 2026, Gross Margin at Castle Biosciences was 77.07%, down 2.87 percentage points year-over-year; for FY2025, it came in at 79.37%, down 2.50 percentage points from FY2024.
- Annual Gross Margin shows a five-year change of -5.17 percentage points (FY2020 to FY2025).
- In prior years, Castle Biosciences' Gross Margin was 81.87% in FY2024 (+2.34 pp), 79.53% in FY2023 (+2.89 pp), 76.64% in FY2022 (-6.54 pp) and 83.18% in FY2021 (-1.36 pp).
- Quarterly Gross Margin has run from a low of 75.17% in Q4 2022 to a high of 83.31% in Q2 2024 over five years.
- On a year-over-year basis, Gross Margin has declined in each of the last six quarters, with an average year-over-year change of -2.38 percentage points over the last eight quarters.
- The strongest year-over-year quarter for Gross Margin in the past five years was Q4 2023, with a gain of 6.04 percentage points; the weakest was Q1 2022, with a drop of 8.86 percentage points.
- According to Business Quant data, Gross Margin for the three prior quarters was 77.11% (Q2 2026), 75.46% (Q1 2026) and 78.95% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 105.29 Bn | 103.13 Bn | 17.03 Bn | 85.78% |
| 2 | Natera | 46.06 Bn | 41.68 Bn | 513.47 Mn | 64.67% |
| 3 | Labcorp Holdings | 30.09 Bn | 28.19 Bn | 1.11 Bn | 29.08% |
| 4 | Quest Diagnostics | 28.58 Bn | 26.66 Bn | 1.04 Bn | 33.65% |
| 5 | Guardant Health | 20.44 Bn | 16.05 Bn | 236.15 Mn | 65.42% |
| 6 | BrightSpring Health Services | 14.16 Bn | 11.04 Bn | 518.55 Mn | 12.31% |
| 7 | Encompass Health | 13.83 Bn | 14.29 Bn | 1.54 Bn | 95.96% |
| 8 | Tempus AI | 12.69 Bn | 9.84 Bn | 266.70 Mn | 64.81% |
| 9 | Davita | 11.06 Bn | 9.92 Bn | 1.13 Bn | 31.50% |
| 10 | Castle Biosciences | 1.04 Bn | -65.97 Mn | 78.97 Mn | 76.75% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 76.75% |
| Jun 30, 2026 | 77.11% |
| Mar 31, 2026 | 75.46% |
| Dec 31, 2025 | 78.95% |
| Sep 30, 2025 | 77.48% |
| Jun 30, 2025 | 79.55% |
| Mar 31, 2025 | 81.38% |
| Dec 31, 2024 | 81.25% |
| Sep 30, 2024 | 81.80% |
| Jun 30, 2024 | 83.31% |
| Mar 31, 2024 | 80.96% |
| Dec 31, 2023 | 81.21% |
| Sep 30, 2023 | 81.59% |
| Jun 30, 2023 | 77.94% |
| Mar 31, 2023 | 75.78% |
| Dec 31, 2022 | 75.17% |
| Sep 30, 2022 | 76.06% |
| Jun 30, 2022 | 77.94% |
| Mar 31, 2022 | 77.86% |
| Dec 31, 2021 | 81.64% |
API Access
Castle Biosciences Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=CSTL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();