Growth Metrics

Castle Biosciences (CSTL) Gross Margin (2018 - 2025)

Castle Biosciences (CSTL) has disclosed Gross Margin for 8 consecutive years, with 78.95% as the latest value for Q4 2025.

  • Quarterly Gross Margin fell 230.0% to 78.95% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 79.37% through Dec 2025, down 250.0% year-over-year, with the annual reading at 79.37% for FY2025, 250.0% down from the prior year.
  • Gross Margin hit 78.95% in Q4 2025 for Castle Biosciences, up from 77.48% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 86.73% in Q1 2021 to a low of 75.17% in Q4 2022.
  • Historically, Gross Margin has averaged 80.06% across 5 years, with a median of 80.9% in 2021.
  • Biggest five-year swings in Gross Margin: plummeted -886bps in 2022 and later surged 604bps in 2023.
  • Year by year, Gross Margin stood at 81.64% in 2021, then fell by -8bps to 75.17% in 2022, then rose by 8bps to 81.21% in 2023, then grew by 0bps to 81.25% in 2024, then decreased by -3bps to 78.95% in 2025.
  • Business Quant data shows Gross Margin for CSTL at 78.95% in Q4 2025, 77.48% in Q3 2025, and 79.55% in Q2 2025.