Castle Biosciences (CSTL) Net Margin (2018 - 2026)
Castle Biosciences' (CSTL) quarterly Net Margin came in at 17.35% in Q1 2026, up 1202.0% year-on-year from 1.33% in Q1 2025, and down 547.52% quarter-over-quarter from 2.68% in Q4 2025.
Castle Biosciences (CSTL) Net Margin (2018 - 2026) Analysis & Trends
Castle Biosciences has disclosed Net Margin across 9 years of filings, most recently posting 17.35% for Q1 2026.
- Net Margin for Q1 2026 came in at 17.35%, up 1202.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 3.78% (down 231.0% YoY), and the FY2025 annual result was 7.02%, down 1251.0% from the prior year.
- Net Margin came in at 17.35% for Q1 2026 at Castle Biosciences, down from 2.68% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 11.11% in Q4 2024 to a low of 91.7% in Q1 2022.
- The 5-year median for Net Margin is 4.73% (2022), against an average of 20.66%.
- Across the five-year window, Net Margin sank 7294 bps in 2022 and jumped 6600 bps in 2024, its largest moves.
- Castle Biosciences' Net Margin stood at 53.78% in 2022, then jumped by 93 bps to 3.9% in 2023, then jumped by 385 bps to 11.11% in 2024, then tumbled by 124 bps to 2.68% in 2025, then sank by 548 bps to 17.35% in 2026.
- The last three Net Margin figures came in at 17.35% (Q1 2026), 2.68% (Q4 2025), and 0.6% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 30,529.42 Bn | 30,528.96 Bn | 1.11 Bn | -5.68% |
| 2 | Thermo Fisher Scientific | 183.75 Bn | 180.50 Bn | 7.74 Bn | 15.06% |
| 3 | Danaher | 133.13 Bn | 127.43 Bn | 3.59 Bn | 17.29% |
| 4 | Idexx Laboratories | 46.14 Bn | 45.94 Bn | 722.74 Mn | 24.41% |
| 5 | Agilent Technologies | 38.20 Bn | 36.39 Bn | 990.00 Mn | 18.47% |
| 6 | Natera | 31.50 Bn | 30.40 Bn | 696.04 Mn | -12.22% |
| 7 | Iqvia Holdings | 31.34 Bn | 29.36 Bn | 1.36 Bn | 3.40% |
| 8 | Illumina | 24.51 Bn | 23.36 Bn | 721.00 Mn | 12.28% |
| 9 | Mettler Toledo International | 23.53 Bn | 23.47 Bn | 555.82 Mn | 17.89% |
| 10 | Castle Biosciences | 629.76 Mn | 368.04 Mn | 63.15 Mn | -17.35% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -17.35% |
| Dec 31, 2025 | -2.68% |
| Sep 30, 2025 | -0.60% |
| Jun 30, 2025 | 5.25% |
| Mar 31, 2025 | -29.38% |
| Dec 31, 2024 | 11.11% |
| Sep 30, 2024 | 2.65% |
| Jun 30, 2024 | 10.25% |
| Mar 31, 2024 | -3.47% |
| Dec 31, 2023 | -3.90% |
| Sep 30, 2023 | -11.23% |
| Jun 30, 2023 | -37.45% |
| Mar 31, 2023 | -69.47% |
| Dec 31, 2022 | -53.78% |
| Sep 30, 2022 | -54.71% |
| Jun 30, 2022 | -4.73% |
| Mar 31, 2022 | -91.70% |
| Dec 31, 2021 | -53.44% |
| Sep 30, 2021 | -50.23% |
| Jun 30, 2021 | -38.63% |