Castle Biosciences (CSTL) Net Margin (2018 - 2026)

Castle Biosciences (CSTL) posted Net Margin of 1.99% for Q2 2026, up 88.54% sequentially from 17.35% in Q1 2026, and down 728.0% YoY from 0.32% in Q2 2025.

Castle Biosciences (CSTL) Net Margin (2018 - 2026) Analysis & Trends

Castle Biosciences has reported Net Margin for 9 years, with the latest figure at 1.99% in Q2 2026.

  • Quarterly Net Margin fell 728.0% year-over-year to 1.99% in Q2 2026, while the trailing twelve-month figure through Jun 2026 was 5.43% (down 271.0% YoY) and the FY2025 annual result came in at 7.02%, down 1251.0% from the prior year.
  • Net Margin climbed to 1.99% in Q2 2026 per CSTL's latest filing, from 17.35% in the prior quarter.
  • Over five years, Net Margin peaked at 11.11% in Q4 2024 and troughed at 91.7% in Q1 2022.
  • A 5-year average of 19.62% and a median of 4.32% in 2022 frame the typical range for Net Margin.
  • The sharpest annual moves came in 2022 and 2024: Net Margin sank 7294 bps in 2022, then soared 6600 bps in 2024.
  • Over 5 years, Net Margin stood at 53.78% in 2022, then soared by 93 bps to 3.9% in 2023, then soared by 385 bps to 11.11% in 2024, then tumbled by 124 bps to 2.68% in 2025, then gained by 26 bps to 1.99% in 2026.
  • According to Business Quant data, Net Margin over the past three periods registered 1.99%, 17.35%, and 2.68% for Q2 2026, Q1 2026, and Q4 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Thermo Fisher Scientific 213.88 Bn 209.81 Bn 8.34 Bn 14.65%
2 Danaher 140.65 Bn 136.30 Bn 3.61 Bn 13.89%
3 Idexx Laboratories 46.02 Bn 45.83 Bn 779.09 Mn 27.82%
4 Agilent Technologies 39.85 Bn 38.05 Bn 990.00 Mn 18.47%
5 Iqvia Holdings 39.20 Bn 37.12 Bn 1.44 Bn 5.52%
6 Natera 38.80 Bn 37.70 Bn 696.04 Mn -12.22%
7 Illumina 30.11 Bn 28.94 Bn 770.00 Mn 17.86%
8 Mettler Toledo International 28.66 Bn 28.61 Bn 650.22 Mn 22.67%
9 Quest Diagnostics 26.24 Bn 25.61 Bn 1.03 Bn 10.65%
10 Castle Biosciences 926.56 Mn 659.75 Mn 79.85 Mn -1.99%

Historic Data

Download Data
DateValue
Jun 30, 2026 -1.99%
Mar 31, 2026 -17.35%
Dec 31, 2025 -2.68%
Sep 30, 2025 -0.60%
Jun 30, 2025 5.29%
Mar 31, 2025 -29.38%
Dec 31, 2024 11.11%
Sep 30, 2024 2.65%
Jun 30, 2024 10.25%
Mar 31, 2024 -3.47%
Dec 31, 2023 -3.90%
Sep 30, 2023 -11.23%
Jun 30, 2023 -37.45%
Mar 31, 2023 -69.47%
Dec 31, 2022 -53.78%
Sep 30, 2022 -54.71%
Jun 30, 2022 -4.73%
Mar 31, 2022 -91.70%
Dec 31, 2021 -53.44%
Sep 30, 2021 -50.23%