Growth Metrics

Castle Biosciences (CSTL) Net Margin (2018 - 2026)

Castle Biosciences' Net Margin history spans 8 years, with the latest figure at 2.68% for Q4 2025.

  • On a quarterly basis, Net Margin fell 1379.0% to 2.68% in Q4 2025 year-over-year; TTM through Dec 2025 was 7.02%, a 1251.0% decrease, with the full-year FY2025 number at 7.02%, down 1251.0% from a year prior.
  • Net Margin hit 2.68% in Q4 2025 for Castle Biosciences, down from 0.6% in the prior quarter.
  • Over the last five years, Net Margin for CSTL hit a ceiling of 11.11% in Q4 2024 and a floor of 91.7% in Q1 2022.
  • Historically, Net Margin has averaged 24.75% across 5 years, with a median of 15.0% in 2021.
  • Biggest five-year swings in Net Margin: plummeted -7294bps in 2022 and later soared 6600bps in 2024.
  • Tracing CSTL's Net Margin over 5 years: stood at 53.44% in 2021, then dropped by -1bps to 53.78% in 2022, then surged by 93bps to 3.9% in 2023, then surged by 385bps to 11.11% in 2024, then crashed by -124bps to 2.68% in 2025.
  • Business Quant data shows Net Margin for CSTL at 2.68% in Q4 2025, 0.6% in Q3 2025, and 5.25% in Q2 2025.