Castle Biosciences (CSTL) Net Margin (2018 - 2026)
Castle Biosciences (CSTL) posted Net Margin of 17.35% for Q1 2026, down 547.52% sequentially from 2.68% in Q4 2025, and up 1202.0% YoY from 1.33% in Q1 2025.
Castle Biosciences (CSTL) Net Margin (2018 - 2026) Analysis & Trends
Castle Biosciences (CSTL) has 9 years of Net Margin data on file, last reported at 17.35% in Q1 2026.
- Quarterly Net Margin rose 1202.0% year-over-year to 17.35% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 3.78% (down 231.0% YoY) and the FY2025 annual result came in at 7.02%, down 1251.0% from the prior year.
- Net Margin slipped to 17.35% in Q1 2026 per CSTL's latest filing, from 2.68% in the prior quarter.
- The five-year high for Net Margin was 11.11% in Q4 2024, with the low at 91.7% in Q1 2022.
- Average Net Margin over 5 years is 20.66%, with a median of 4.73% recorded in 2022.
- Year-over-year, Net Margin tumbled 7294 bps in 2022 and surged 6600 bps in 2024.
- Castle Biosciences' Net Margin stood at 53.78% in 2022, then jumped by 93 bps to 3.9% in 2023, then jumped by 385 bps to 11.11% in 2024, then plunged by 124 bps to 2.68% in 2025, then slumped by 548 bps to 17.35% in 2026.
- Business Quant data shows CSTL's Net Margin at 17.35% in Q1 2026, 2.68% in Q4 2025, and 0.6% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -5.68% |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 15.06% |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 17.29% |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 24.41% |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -12.22% |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 18.47% |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 3.40% |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 12.28% |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 17.89% |
| 10 | Castle Biosciences | 738.56 Mn | 476.84 Mn | 63.15 Mn | -17.35% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -17.35% |
| Dec 31, 2025 | -2.68% |
| Sep 30, 2025 | -0.60% |
| Jun 30, 2025 | 5.25% |
| Mar 31, 2025 | -29.38% |
| Dec 31, 2024 | 11.11% |
| Sep 30, 2024 | 2.65% |
| Jun 30, 2024 | 10.25% |
| Mar 31, 2024 | -3.47% |
| Dec 31, 2023 | -3.90% |
| Sep 30, 2023 | -11.23% |
| Jun 30, 2023 | -37.45% |
| Mar 31, 2023 | -69.47% |
| Dec 31, 2022 | -53.78% |
| Sep 30, 2022 | -54.71% |
| Jun 30, 2022 | -4.73% |
| Mar 31, 2022 | -91.70% |
| Dec 31, 2021 | -53.44% |
| Sep 30, 2021 | -50.23% |
| Jun 30, 2021 | -38.63% |