Castle Biosciences (CSTL) Operating Expenses (2018 - 2026)
Castle Biosciences' (CSTL) quarterly Operating Expenses came in at $106.6 million in Q2 2026, up 17.89% year-over-year from $90.4 million in Q2 2025, and up 4.44% quarter-over-quarter from $102.1 million in Q1 2026.
Castle Biosciences (CSTL) Operating Expenses (2018 - 2026) Analysis & Trends
Castle Biosciences has disclosed Operating Expenses across 9 years of filings, most recently posting $106.6 million for Q2 2026.
- In Q2 2026, Operating Expenses rose 17.89% year-over-year to $106.6 million; the TTM figure through Jun 2026 stood at $389.4 million (up 5.43% YoY), while the FY2025 annual figure was $387.0 million, up 19.68% from the prior year.
- Operating Expenses came in at $106.6 million for Q2 2026 at Castle Biosciences, up from $102.1 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $115.9 million in Q1 2025 to a low of $38.8 million in Q2 2022.
- Average Operating Expenses over 5 years is $78.7 million, with a median of $79.6 million recorded in 2024.
- Year-over-year, Operating Expenses jumped 89.57% in 2022 and slipped 11.93% in 2026.
- Over 5 years, Operating Expenses stood at $61.2 million in 2022, then advanced by 17.34% to $71.8 million in 2023, then climbed by 14.6% to $82.3 million in 2024, then advanced by 10.43% to $90.8 million in 2025, then gained by 17.37% to $106.6 million in 2026.
- Per Business Quant data, the three most recent Operating Expenses figures were $106.6 million in Q2 2026, $102.1 million in Q1 2026, and $90.8 million in Q4 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Natera | 53.05 Bn | 51.95 Bn | 486.15 Mn | 828.54 Mn |
| 2 | Quest Diagnostics | 27.19 Bn | 26.87 Bn | 1.03 Bn | 2.58 Bn |
| 3 | Labcorp Holdings | 25.93 Bn | 25.81 Bn | 1.11 Bn | 582.30 Mn |
| 4 | Guardant Health | 23.97 Bn | 22.91 Bn | 219.03 Mn | 464.10 Mn |
| 5 | Tempus AI | 13.64 Bn | 12.82 Bn | 274.25 Mn | 458.40 Mn |
| 6 | Caris Life Sciences | 8.47 Bn | 7.68 Bn | 182.38 Mn | 236.79 Mn |
| 7 | Sotera Health | 5.35 Bn | 4.99 Bn | 177.96 Mn | 68.16 Mn |
| 8 | BillionToOne | 4.96 Bn | 4.41 Bn | 77.11 Mn | 71.60 Mn |
| 9 | Adaptive Biotechnologies | 4.55 Bn | 4.21 Bn | 51.39 Mn | 87.32 Mn |
| 10 | Castle Biosciences | 1.08 Bn | 811.36 Mn | 79.85 Mn | 106.62 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 106.62 Mn |
| Mar 31, 2026 | 102.09 Mn |
| Dec 31, 2025 | 90.84 Mn |
| Sep 30, 2025 | 89.85 Mn |
| Jun 30, 2025 | 90.44 Mn |
| Mar 31, 2025 | 115.92 Mn |
| Dec 31, 2024 | 82.26 Mn |
| Sep 30, 2024 | 80.70 Mn |
| Jun 30, 2024 | 81.99 Mn |
| Mar 31, 2024 | 78.45 Mn |
| Dec 31, 2023 | 71.78 Mn |
| Sep 30, 2023 | 71.13 Mn |
| Jun 30, 2023 | 71.30 Mn |
| Mar 31, 2023 | 73.56 Mn |
| Dec 31, 2022 | 61.17 Mn |
| Sep 30, 2022 | 58.55 Mn |
| Jun 30, 2022 | 38.81 Mn |
| Mar 31, 2022 | 51.37 Mn |
| Dec 31, 2021 | 40.21 Mn |
| Sep 30, 2021 | 35.29 Mn |
Castle Biosciences Operating Expenses API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-expenses&ticker=CSTL&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-expenses", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-expenses&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();