Castle Biosciences (CSTL) Operating Expenses (2018 - 2026)

Castle Biosciences' (CSTL) quarterly Operating Expenses came in at $102.1 million in Q1 2026, down 11.93% year-on-year from $115.9 million in Q1 2025, and up 12.38% quarter-over-quarter from $90.8 million in Q4 2025.

Castle Biosciences (CSTL) Operating Expenses (2018 - 2026) Analysis & Trends

Castle Biosciences has disclosed Operating Expenses across 9 years of filings, most recently posting $102.1 million for Q1 2026.

  • Operating Expenses for Q1 2026 came in at $102.1 million, down 11.93% year-over-year; the trailing twelve-month figure through Mar 2026 was $373.2 million (up 3.42% YoY), and the FY2025 annual result was $387.0 million, up 19.68% from the prior year.
  • Operating Expenses came in at $102.1 million for Q1 2026 at Castle Biosciences, up from $90.8 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $115.9 million in Q1 2025 to a low of $38.8 million in Q2 2022.
  • The 5-year median for Operating Expenses is $78.4 million (2024), against an average of $77.1 million.
  • Across the five-year window, Operating Expenses jumped 113.42% in 2022 and decreased 11.93% in 2026, its largest moves.
  • Castle Biosciences' Operating Expenses stood at $61.2 million in 2022, then advanced by 17.34% to $71.8 million in 2023, then climbed by 14.6% to $82.3 million in 2024, then advanced by 10.43% to $90.8 million in 2025, then increased by 12.38% to $102.1 million in 2026.
  • The last three Operating Expenses figures came in at $102.1 million (Q1 2026), $90.8 million (Q4 2025), and $89.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn 1.31 Bn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 9.14 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 2.25 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 360.15 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 1.44 Bn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 553.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn 790.16 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 512.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 316.87 Mn
10 Castle Biosciences 601.82 Mn 340.09 Mn 63.15 Mn 102.09 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 102.09 Mn
Dec 31, 2025 90.84 Mn
Sep 30, 2025 89.85 Mn
Jun 30, 2025 90.44 Mn
Mar 31, 2025 115.92 Mn
Dec 31, 2024 82.26 Mn
Sep 30, 2024 80.70 Mn
Jun 30, 2024 81.99 Mn
Mar 31, 2024 78.45 Mn
Dec 31, 2023 71.78 Mn
Sep 30, 2023 71.13 Mn
Jun 30, 2023 71.30 Mn
Mar 31, 2023 73.56 Mn
Dec 31, 2022 61.17 Mn
Sep 30, 2022 58.55 Mn
Jun 30, 2022 38.81 Mn
Mar 31, 2022 51.37 Mn
Dec 31, 2021 40.21 Mn
Sep 30, 2021 35.29 Mn
Jun 30, 2021 31.57 Mn