Castle Biosciences (CSTL) EBIT Margin (2018 - 2026)

Castle Biosciences' (CSTL) quarterly EBIT Margin came in at 22.0% in Q1 2026, up 974.0% year-on-year from 2.05% in Q1 2025, and down 400.12% quarter-over-quarter from 4.4% in Q4 2025.

Castle Biosciences (CSTL) EBIT Margin (2018 - 2026) Analysis & Trends

Castle Biosciences has disclosed EBIT Margin across 9 years of filings, most recently posting 22.0% for Q1 2026.

  • EBIT Margin for Q1 2026 came in at 22.0%, up 974.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 9.79% (down 582.0% YoY), and the FY2025 annual result was 12.44%, down 1505.0% from the prior year.
  • EBIT Margin came in at 22.0% for Q1 2026 at Castle Biosciences, down from 4.4% in the prior quarter.
  • In the past five years, EBIT Margin ranged from a high of 5.92% in Q3 2024 to a low of 91.3% in Q1 2022.
  • The 5-year median for EBIT Margin is 11.4% (2022), against an average of 24.96%.
  • Across the five-year window, EBIT Margin slumped 7252 bps in 2022 and surged 6749 bps in 2024, its largest moves.
  • Castle Biosciences' EBIT Margin stood at 59.55% in 2022, then surged by 86 bps to 8.56% in 2023, then soared by 155 bps to 4.69% in 2024, then sank by 194 bps to 4.4% in 2025, then sank by 400 bps to 22.0% in 2026.
  • The last three EBIT Margin figures came in at 22.0% (Q1 2026), 4.4% (Q4 2025), and 8.19% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Waters 30,529.42 Bn 30,528.96 Bn 1.11 Bn -3.71%
2 Thermo Fisher Scientific 183.75 Bn 180.50 Bn 7.74 Bn 16.93%
3 Danaher 133.13 Bn 127.43 Bn 3.59 Bn 22.58%
4 Idexx Laboratories 46.14 Bn 45.94 Bn 722.74 Mn 31.78%
5 Agilent Technologies 38.20 Bn 36.39 Bn 990.00 Mn 21.74%
6 Natera 31.50 Bn 30.40 Bn 696.04 Mn -13.42%
7 Iqvia Holdings 31.34 Bn 29.36 Bn 1.36 Bn 12.38%
8 Illumina 24.51 Bn 23.36 Bn 721.00 Mn 19.16%
9 Mettler Toledo International 23.53 Bn 23.47 Bn 555.82 Mn 25.23%
10 Castle Biosciences 629.76 Mn 368.04 Mn 63.15 Mn -22.00%

Historic Data

Download Data
DateValue
Mar 31, 2026 -22.00%
Dec 31, 2025 -4.40%
Sep 30, 2025 -8.19%
Jun 30, 2025 -4.93%
Mar 31, 2025 -31.74%
Dec 31, 2024 4.69%
Sep 30, 2024 5.92%
Jun 30, 2024 5.76%
Mar 31, 2024 -7.50%
Dec 31, 2023 -8.56%
Sep 30, 2023 -15.68%
Jun 30, 2023 -42.20%
Mar 31, 2023 -74.99%
Dec 31, 2022 -59.55%
Sep 30, 2022 -58.19%
Jun 30, 2022 -11.40%
Mar 31, 2022 -91.30%
Dec 31, 2021 -60.59%
Sep 30, 2021 -50.33%
Jun 30, 2021 -38.71%