Castle Biosciences Inc (CSTL) Institutional Ownership

Institutions by Trading Activity

25,050,000Shares Outstanding

233Shares held by institutions

$9,166Value of institutional holdings

0.13%Institutional ownership %

38.99%Shares Changed QoQ

5No. of institutional investors

According to SEC filings for the period ending December 2025, Castle Biosciences Inc (NASDAQ:CSTL) is held by 5 institutional firms.

These investors collectively held 0.1% of the company's total shares outstanding in December 2025, down from 106.0% in September 2025.
On a quarter-over-quarter basis, institutional holdings shifted by 38.99%, with a year-over-year a decrease of 97.42% in the count of filers.
The latest 13F cycle for Castle Biosciences reveals that of 5 total investors, 3 funds grew their exposure, whereas 0 reduced theirs and 2 made no changes.
This class of investors increased its holdings in Castle Biosciences to 31.74K shares for the 13F-cycle ending December 2025, up by 8.90K shares quarter on quarter, and down 26.25Mn shares year over year.
As of December 31, 2025, SG Americas Securities, LLC held Castle Biosciences's largest shareholding position with over 21.26K shares, representing 0.08% of total outstanding shares.
Among the most significant buyers of Castle Biosciences during December 2025 were SG Americas Securities, LLC (8.20K), Green Alpha Advisors, LLC (698), True Wealth Design, LLC (4).
The top 5 institutional holders of Castle Biosciences for the quarter ending December 2025 included SG Americas Securities, LLC (21.26K), Green Alpha Advisors, LLC (10.24K), Versant Capital Management, Inc (181), GAMMA Investing LLC (52), True Wealth Design, LLC (5).

233 Total Shares Held

Rows:

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	30 Sep, 2025	3,189,896	35,217	1.12%	$72,633,931.00
VANGUARD GROUP INC	30 Sep, 2025	2,172,318	2,290	0.11%	$49,463,681.00
PRINCIPAL FINANCIAL GROUP INC	30 Sep, 2025	1,794,355	-4,619	-0.26%	$40,857,463.00
Portolan Capital Management, LLC	30 Sep, 2025	1,515,111	25,539	1.71%	$34,499,077.00
DIMENSIONAL FUND ADVISORS LP	30 Sep, 2025	1,474,089	96,084	6.97%	$33,564,113.00
Nuveen, LLC	30 Sep, 2025	957,081	-116,026	-10.81%	$21,792,735.00
BRAIDWELL LP	30 Sep, 2025	822,735	0	0.00%	$18,733,676.00
STATE STREET CORP	30 Sep, 2025	724,080	16,393	2.32%	$16,487,302.00
AIGH Capital Management LLC	30 Sep, 2025	707,287	707,287	0.00%	$16,104,925.00
GEODE CAPITAL MANAGEMENT, LLC	30 Sep, 2025	698,610	8,684	1.26%	$15,909,607.00
WASATCH ADVISORS LP	30 Sep, 2025	669,120	-380,653	-36.26%	$15,235,862.00
Allianz Asset Management GmbH	30 Sep, 2025	648,351	-65,391	-9.16%	$14,762,953.00
PALISADE CAPITAL MANAGEMENT, LP	30 Sep, 2025	638,656	63,540	11.05%	$14,542,197.00
MILLENNIUM MANAGEMENT LLC	30 Sep, 2025	575,089	146,692	34.24%	$13,094,777.00
RENAISSANCE TECHNOLOGIES LLC	30 Sep, 2025	562,600	-107,900	-16.09%	$12,810,402.00
SCHRODER INVESTMENT MANAGEMENT GROUP	30 Sep, 2025	494,950	-153,622	-23.69%	$11,067,082.00
Parkman Healthcare Partners LLC	30 Sep, 2025	475,568	123,306	35.00%	$10,828,683.00
ACADIAN ASSET MANAGEMENT LLC	30 Sep, 2025	451,652	-92,598	-17.01%	$10,281.00
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	30 Sep, 2025	400,000	400,000	0.00%	$9,108,000.00
SILVERCREST ASSET MANAGEMENT GROUP LLC	30 Sep, 2025	367,888	87,929	31.41%	$8,376,810.00

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