Growth Metrics

Castle Biosciences (CSTL) EBITDA Margin (2018 - 2025)

Castle Biosciences (CSTL) has disclosed EBITDA Margin for 8 consecutive years, with 4.4% as the latest value for Q4 2025.

  • Quarterly EBITDA Margin fell 909.0% to 4.4% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 12.44% through Dec 2025, down 1505.0% year-over-year, with the annual reading at 12.44% for FY2025, 1505.0% down from the prior year.
  • EBITDA Margin hit 4.4% in Q4 2025 for Castle Biosciences, up from 8.19% in the prior quarter.
  • In the past five years, EBITDA Margin ranged from a high of 5.92% in Q3 2024 to a low of 91.7% in Q1 2022.
  • Historically, EBITDA Margin has averaged 26.46% across 5 years, with a median of 17.22% in 2023.
  • Biggest five-year swings in EBITDA Margin: plummeted -7294bps in 2022 and later skyrocketed 6749bps in 2024.
  • Year by year, EBITDA Margin stood at 25.68% in 2021, then plummeted by -132bps to 59.55% in 2022, then skyrocketed by 86bps to 8.56% in 2023, then surged by 155bps to 4.69% in 2024, then crashed by -194bps to 4.4% in 2025.
  • Business Quant data shows EBITDA Margin for CSTL at 4.4% in Q4 2025, 8.19% in Q3 2025, and 4.93% in Q2 2025.