Castle Biosciences (CSTL) EBITDA Margin (2018 - 2026)

Castle Biosciences (CSTL) posted EBITDA Margin of 2.96% for Q2 2026, up 86.52% sequentially from 22.0% in Q1 2026, and up 197.0% YoY from 1.0% in Q2 2025.

Castle Biosciences (CSTL) EBITDA Margin (2018 - 2026) Analysis & Trends

Castle Biosciences has reported EBITDA Margin for 9 years, with the latest figure at 2.96% in Q2 2026.

  • Quarterly EBITDA Margin rose 197.0% year-over-year to 2.96% in Q2 2026, while the trailing twelve-month figure through Jun 2026 was 8.99% (down 233.0% YoY) and the FY2025 annual result came in at 12.44%, down 1505.0% from the prior year.
  • EBITDA Margin advanced to 2.96% in Q2 2026 per CSTL's latest filing, from 22.0% in the prior quarter.
  • Over five years, EBITDA Margin peaked at 5.92% in Q3 2024 and troughed at 91.3% in Q1 2022.
  • A 5-year average of 23.73% and a median of 9.98% in 2022 frame the typical range for EBITDA Margin.
  • The sharpest annual moves came in 2022 and 2024: EBITDA Margin slumped 7252 bps in 2022, then jumped 6749 bps in 2024.
  • Over 5 years, EBITDA Margin stood at 59.55% in 2022, then jumped by 86 bps to 8.56% in 2023, then surged by 155 bps to 4.69% in 2024, then sank by 194 bps to 4.4% in 2025, then jumped by 33 bps to 2.96% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 2.96%, 22.0%, and 4.4% for Q2 2026, Q1 2026, and Q4 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Thermo Fisher Scientific 213.88 Bn 209.81 Bn 8.34 Bn 17.40%
2 Danaher 140.65 Bn 136.30 Bn 3.61 Bn 17.99%
3 Idexx Laboratories 46.02 Bn 45.83 Bn 779.09 Mn 34.98%
4 Agilent Technologies 39.85 Bn 38.05 Bn 990.00 Mn 21.74%
5 Iqvia Holdings 39.20 Bn 37.12 Bn 1.44 Bn 11.58%
6 Natera 38.80 Bn 37.70 Bn 696.04 Mn -13.42%
7 Illumina 30.11 Bn 28.94 Bn 770.00 Mn 21.14%
8 Mettler Toledo International 28.66 Bn 28.61 Bn 650.22 Mn 31.97%
9 Quest Diagnostics 26.24 Bn 25.61 Bn 1.03 Bn 15.08%
10 Castle Biosciences 926.56 Mn 659.75 Mn 79.85 Mn -2.96%

Historic Data

Download Data
DateValue
Jun 30, 2026 -2.96%
Mar 31, 2026 -22.00%
Dec 31, 2025 -4.40%
Sep 30, 2025 -8.19%
Jun 30, 2025 -4.93%
Mar 31, 2025 -31.74%
Dec 31, 2024 4.69%
Sep 30, 2024 5.92%
Jun 30, 2024 5.76%
Mar 31, 2024 -7.50%
Dec 31, 2023 -8.56%
Sep 30, 2023 -15.68%
Jun 30, 2023 -42.20%
Mar 31, 2023 -74.99%
Dec 31, 2022 -59.55%
Sep 30, 2022 -58.19%
Jun 30, 2022 -11.40%
Mar 31, 2022 -91.30%
Dec 31, 2021 -60.59%
Sep 30, 2021 -50.33%