Castle Biosciences (CSTL) Gross Profit (2018 - 2026)
Castle Biosciences (CSTL) posted Gross Profit of $78.97 million for Q3 2026, up 22.7% from $64.34 million a year earlier but down 1.1% from the prior quarter.
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Analysis
Castle Biosciences (CSTL) Gross Profit (2018 - 2026) Analysis & Trends
For the trailing twelve months through Sep 30, 2026, Gross Profit at Castle Biosciences was $290.66 million, up 5.8% year-over-year; for FY2025, it came in at $273.2 million, up 0.5% from FY2024.
- Annual Gross Profit has increased for seven consecutive years, with a five-year compound annual growth rate of 38.8% (FY2020 to FY2025).
- In prior years, Castle Biosciences' Gross Profit was $271.86 million in FY2024 (+55.5%), $174.81 million in FY2023 (+66.4%), $105.03 million in FY2022 (+34.2%) and $78.26 million in FY2021 (+47.8%).
- Quarterly Gross Profit has run from a low of $20.44 million in Q4 2021 to a high of $79.85 million in Q2 2026 over five years.
- On a year-over-year basis, Gross Profit increased in four of the last eight quarters, with growth averaging 7.9%.
- The strongest year-over-year quarter for Gross Profit in the past five years was Q4 2023, with growth of 86.3%; the weakest was Q1 2026, with a decline of 11.8%.
- According to Business Quant data, Gross Profit for the three prior quarters was $79.85 million (Q2 2026), $63.15 million (Q1 2026) and $68.7 million (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | HCA Healthcare | 105.29 Bn | 103.13 Bn | 17.03 Bn |
| 2 | Natera | 46.06 Bn | 41.68 Bn | 513.47 Mn |
| 3 | Labcorp Holdings | 30.09 Bn | 28.19 Bn | 1.11 Bn |
| 4 | Quest Diagnostics | 28.58 Bn | 26.66 Bn | 1.04 Bn |
| 5 | Guardant Health | 20.44 Bn | 16.05 Bn | 236.15 Mn |
| 6 | BrightSpring Health Services | 14.16 Bn | 11.04 Bn | 518.55 Mn |
| 7 | Encompass Health | 13.83 Bn | 14.29 Bn | 1.54 Bn |
| 8 | Tempus AI | 12.69 Bn | 9.84 Bn | 266.70 Mn |
| 9 | Davita | 11.06 Bn | 9.92 Bn | 1.13 Bn |
| 10 | Castle Biosciences | 1.04 Bn | -65.97 Mn | 78.97 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 78.97 Mn |
| Jun 30, 2026 | 79.85 Mn |
| Mar 31, 2026 | 63.15 Mn |
| Dec 31, 2025 | 68.70 Mn |
| Sep 30, 2025 | 64.34 Mn |
| Jun 30, 2025 | 68.56 Mn |
| Mar 31, 2025 | 71.61 Mn |
| Dec 31, 2024 | 70.13 Mn |
| Sep 30, 2024 | 70.17 Mn |
| Jun 30, 2024 | 72.48 Mn |
| Mar 31, 2024 | 59.08 Mn |
| Dec 31, 2023 | 53.70 Mn |
| Sep 30, 2023 | 50.17 Mn |
| Jun 30, 2023 | 39.08 Mn |
| Mar 31, 2023 | 31.86 Mn |
| Dec 31, 2022 | 28.82 Mn |
| Sep 30, 2022 | 28.15 Mn |
| Jun 30, 2022 | 27.15 Mn |
| Mar 31, 2022 | 20.91 Mn |
| Dec 31, 2021 | 20.44 Mn |
API Access
Castle Biosciences Gross Profit API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-profit&ticker=CSTL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-profit", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-profit&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();