Castle Biosciences (CSTL) Price to Earnings (2019 - 2026)
Castle Biosciences' (CSTL) quarterly Price to Earnings came in at 353.22 in Q2 2026, down 371.99% year-over-year from 129.87 in Q2 2025, and down 589.66% quarter-over-quarter from 51.22 in Q1 2026.
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Analysis
Castle Biosciences (CSTL) Price to Earnings (2019 - 2026) Analysis & Trends
Castle Biosciences has disclosed Price to Earnings across 8 years of filings, most recently posting 353.22 for Q2 2026.
- In Q2 2026, Price to Earnings fell 371.99% year-over-year to 353.22; the TTM figure through Jun 2026 stood at 37.48 (up 40.27% YoY), while the FY2025 annual figure was 47.8, down 214.9% from the prior year.
- Price to Earnings came in at 353.22 for Q2 2026 at Castle Biosciences, down from 51.22 in the prior quarter.
- In the past five years, Price to Earnings ranged from a high of 351.64 in Q3 2024 to a low of 1325.38 in Q3 2025.
- Average Price to Earnings over 5 years is 147.58, with a median of 40.18 recorded in 2022.
- The largest YoY upside for Price to Earnings was 634.61% in 2024 against a maximum downside of 1061.44% in 2024.
- Over 5 years, Price to Earnings stood at 30.32 in 2022, then plunged by 656.25% to 229.27 in 2023, then surged by 134.52% to 79.15 in 2024, then tumbled by 725.62% to 495.2 in 2025, then increased by 28.67% to 353.22 in 2026.
- Per Business Quant data, the three most recent Price to Earnings figures were 353.22 in Q2 2026, 51.22 in Q1 2026, and 495.2 in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Natera | 53.05 Bn | 51.95 Bn | 486.15 Mn |
| 2 | Quest Diagnostics | 27.19 Bn | 26.87 Bn | 1.03 Bn |
| 3 | Labcorp Holdings | 25.93 Bn | 25.81 Bn | 1.11 Bn |
| 4 | Guardant Health | 23.97 Bn | 22.91 Bn | 219.03 Mn |
| 5 | Tempus AI | 13.64 Bn | 12.82 Bn | 274.25 Mn |
| 6 | Caris Life Sciences | 8.47 Bn | 7.68 Bn | 182.38 Mn |
| 7 | Sotera Health | 5.35 Bn | 4.99 Bn | 177.96 Mn |
| 8 | BillionToOne | 4.96 Bn | 4.41 Bn | 77.11 Mn |
| 9 | Adaptive Biotechnologies | 4.55 Bn | 4.21 Bn | 51.39 Mn |
| 10 | Castle Biosciences | 1.08 Bn | 811.36 Mn | 79.85 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -353.22 |
| Mar 31, 2026 | -51.22 |
| Dec 31, 2025 | -495.20 |
| Sep 30, 2025 | -1,325.38 |
| Jun 30, 2025 | 129.87 |
| Mar 31, 2025 | -22.34 |
| Dec 31, 2024 | 79.15 |
| Sep 30, 2024 | 351.64 |
| Jun 30, 2024 | 67.63 |
| Mar 31, 2024 | -241.13 |
| Dec 31, 2023 | -229.27 |
| Sep 30, 2023 | -65.78 |
| Jun 30, 2023 | -19.57 |
| Mar 31, 2023 | -20.76 |
| Dec 31, 2022 | -30.32 |
| Sep 30, 2022 | -33.94 |
| Jun 30, 2022 | -350.19 |
| Mar 31, 2022 | -46.43 |
| Dec 31, 2021 | -169.20 |
| Sep 30, 2021 | -142.61 |
API Access
Castle Biosciences Price to Earnings API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=price-to-earnings&ticker=CSTL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "price-to-earnings", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=price-to-earnings&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();