Castle Biosciences (CSTL) Operating Margin (2018 - 2026)
Castle Biosciences (CSTL) reported Operating Margin of -2.65% for Q3 2026, up 5.54 percentage points from -8.19% a year earlier and up 0.31 percentage points from the prior quarter.
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Analysis
Castle Biosciences (CSTL) Operating Margin (2018 - 2026) Analysis & Trends
Over the twelve months ended Sep 30, 2026, Castle Biosciences' Operating Margin came in at -7.43%, up 2.73 percentage points year-over-year; for FY2025, it was -12.44%, down 15.05 percentage points from FY2024.
- Operating Margin has a five-year change of -1.99 percentage points (FY2020 to FY2025).
- By year, Operating Margin came in at 2.61% in FY2024 (+33.54 pp), -30.93% in FY2023 (+22.24 pp), -53.16% in FY2022 (-10.56 pp) and -42.60% in FY2021 (-32.16 pp).
- The Q3 2026 figure ranks as the highest quarterly Operating Margin since Q4 2024.
- Year over year, Operating Margin has now increased in each of the last three quarters, with an average year-over-year change of -3.46 percentage points over the last eight quarters.
- The high point for year-over-year Operating Margin in five years was Q1 2024 (a gain of 67.49 percentage points); the low point was Q1 2022 (a drop of 72.52 percentage points).
- Per Business Quant data, the three quarters before Q3 2026 came in at -2.96% (Q2 2026), -22.00% (Q1 2026) and -4.40% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 105.29 Bn | 103.13 Bn | 17.03 Bn | 15.00% |
| 2 | Natera | 46.06 Bn | 41.68 Bn | 513.47 Mn | -8.60% |
| 3 | Labcorp Holdings | 30.09 Bn | 28.19 Bn | 1.11 Bn | 10.55% |
| 4 | Quest Diagnostics | 28.58 Bn | 26.66 Bn | 1.04 Bn | 15.47% |
| 5 | Guardant Health | 20.44 Bn | 16.05 Bn | 236.15 Mn | -36.78% |
| 6 | BrightSpring Health Services | 14.16 Bn | 11.04 Bn | 518.55 Mn | 3.81% |
| 7 | Encompass Health | 13.83 Bn | 14.29 Bn | 1.54 Bn | 13.86% |
| 8 | Tempus AI | 12.69 Bn | 9.84 Bn | 266.70 Mn | -13.82% |
| 9 | Davita | 11.06 Bn | 9.92 Bn | 1.13 Bn | 13.95% |
| 10 | Castle Biosciences | 1.04 Bn | -65.97 Mn | 78.97 Mn | -2.65% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -2.65% |
| Jun 30, 2026 | -2.96% |
| Mar 31, 2026 | -22.00% |
| Dec 31, 2025 | -4.40% |
| Sep 30, 2025 | -8.19% |
| Jun 30, 2025 | -4.93% |
| Mar 31, 2025 | -31.74% |
| Dec 31, 2024 | 4.69% |
| Sep 30, 2024 | 5.92% |
| Jun 30, 2024 | 5.76% |
| Mar 31, 2024 | -7.50% |
| Dec 31, 2023 | -8.56% |
| Sep 30, 2023 | -15.68% |
| Jun 30, 2023 | -42.20% |
| Mar 31, 2023 | -74.99% |
| Dec 31, 2022 | -59.55% |
| Sep 30, 2022 | -58.19% |
| Jun 30, 2022 | -11.40% |
| Mar 31, 2022 | -91.30% |
| Dec 31, 2021 | -60.59% |
API Access
Castle Biosciences Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=CSTL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();