Castle Biosciences (CSTL) Operating Income (2018 - 2026)
Castle Biosciences (CSTL) posted Operating Income of -$18.4 million for Q1 2026, down 380.98% sequentially from -$3.8 million in Q4 2025, and up 34.09% YoY from -$13.7 million in Q1 2025.
Castle Biosciences (CSTL) Operating Income (2018 - 2026) Analysis & Trends
Castle Biosciences (CSTL) has 9 years of Operating Income data on file, last reported at -$18.4 million in Q1 2026.
- Quarterly Operating Income rose 34.09% year-over-year to -$18.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$33.3 million (down 141.45% YoY) and the FY2025 annual result came in at -$42.8 million, down 593.77% from the prior year.
- Operating Income retreated to -$18.4 million in Q1 2026 per CSTL's latest filing, from -$3.8 million in the prior quarter.
- The five-year high for Operating Income was $5.1 million in Q3 2024, with the low at -$31.5 million in Q1 2023.
- Average Operating Income over 5 years is -$11.4 million, with a median of -$6.8 million recorded in 2025.
- Year-over-year, Operating Income plunged 472.27% in 2022 and jumped 171.58% in 2024.
- Castle Biosciences' Operating Income stood at -$22.8 million in 2022, then surged by 75.22% to -$5.7 million in 2023, then surged by 171.58% to $4.0 million in 2024, then sank by 194.49% to -$3.8 million in 2025, then sank by 380.98% to -$18.4 million in 2026.
- Business Quant data shows CSTL's Operating Income at -$18.4 million in Q1 2026, -$3.8 million in Q4 2025, and -$6.8 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -47.00 Mn |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 1.86 Bn |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 1.34 Bn |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 362.59 Mn |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -93.52 Mn |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 399.00 Mn |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 514.00 Mn |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 209.00 Mn |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 238.95 Mn |
| 10 | Castle Biosciences | 738.56 Mn | 476.84 Mn | 63.15 Mn | -18.41 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -18.41 Mn |
| Dec 31, 2025 | -3.83 Mn |
| Sep 30, 2025 | -6.80 Mn |
| Jun 30, 2025 | -4.25 Mn |
| Mar 31, 2025 | -27.93 Mn |
| Dec 31, 2024 | 4.05 Mn |
| Sep 30, 2024 | 5.08 Mn |
| Jun 30, 2024 | 5.01 Mn |
| Mar 31, 2024 | -5.47 Mn |
| Dec 31, 2023 | -5.66 Mn |
| Sep 30, 2023 | -9.64 Mn |
| Jun 30, 2023 | -21.16 Mn |
| Mar 31, 2023 | -31.52 Mn |
| Dec 31, 2022 | -22.83 Mn |
| Sep 30, 2022 | -21.54 Mn |
| Jun 30, 2022 | -3.97 Mn |
| Mar 31, 2022 | -24.52 Mn |
| Dec 31, 2021 | -15.17 Mn |
| Sep 30, 2021 | -11.81 Mn |
| Jun 30, 2021 | -8.81 Mn |