Castle Biosciences (CSTL) Operating Income (2018 - 2026)
Castle Biosciences' (CSTL) quarterly Operating Income came in at -$3.1 million in Q2 2026, up 27.78% year-over-year from -$2.4 million in Q2 2025, and up 83.32% quarter-over-quarter from -$18.4 million in Q1 2026.
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Analysis
Castle Biosciences (CSTL) Operating Income (2018 - 2026) Analysis & Trends
Castle Biosciences has disclosed Operating Income across 9 years of filings, most recently posting -$3.1 million for Q2 2026.
- In Q2 2026, Operating Income rose 27.78% year-over-year to -$3.1 million; the TTM figure through Jun 2026 stood at -$32.1 million (down 39.3% YoY), while the FY2025 annual figure was -$42.8 million, down 593.77% from the prior year.
- Operating Income came in at -$3.1 million for Q2 2026 at Castle Biosciences, up from -$18.4 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $5.1 million in Q3 2024 to a low of -$31.5 million in Q1 2023.
- Average Operating Income over 5 years is -$10.9 million, with a median of -$6.2 million recorded in 2023.
- Year-over-year, Operating Income sank 472.27% in 2022 and jumped 171.58% in 2024.
- Over 5 years, Operating Income stood at -$22.8 million in 2022, then surged by 75.22% to -$5.7 million in 2023, then surged by 171.58% to $4.0 million in 2024, then slumped by 194.49% to -$3.8 million in 2025, then climbed by 19.78% to -$3.1 million in 2026.
- Per Business Quant data, the three most recent Operating Income figures were -$3.1 million in Q2 2026, -$18.4 million in Q1 2026, and -$3.8 million in Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Natera | 53.05 Bn | 51.95 Bn | 486.15 Mn | -75.79 Mn |
| 2 | Quest Diagnostics | 27.19 Bn | 26.87 Bn | 1.03 Bn | 459.00 Mn |
| 3 | Labcorp Holdings | 25.93 Bn | 25.81 Bn | 1.11 Bn | 451.60 Mn |
| 4 | Guardant Health | 23.97 Bn | 22.91 Bn | 219.03 Mn | -129.12 Mn |
| 5 | Tempus AI | 13.64 Bn | 12.82 Bn | 274.25 Mn | -75.91 Mn |
| 6 | Caris Life Sciences | 8.47 Bn | 7.68 Bn | 182.38 Mn | 26.93 Mn |
| 7 | Sotera Health | 5.35 Bn | 4.99 Bn | 177.96 Mn | 109.81 Mn |
| 8 | BillionToOne | 4.96 Bn | 4.41 Bn | 77.11 Mn | 5.50 Mn |
| 9 | Adaptive Biotechnologies | 4.55 Bn | 4.21 Bn | 51.39 Mn | -15.77 Mn |
| 10 | Castle Biosciences | 1.08 Bn | 811.36 Mn | 79.85 Mn | -3.07 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3.07 Mn |
| Mar 31, 2026 | -18.41 Mn |
| Dec 31, 2025 | -3.83 Mn |
| Sep 30, 2025 | -6.80 Mn |
| Jun 30, 2025 | -4.25 Mn |
| Mar 31, 2025 | -27.93 Mn |
| Dec 31, 2024 | 4.05 Mn |
| Sep 30, 2024 | 5.08 Mn |
| Jun 30, 2024 | 5.01 Mn |
| Mar 31, 2024 | -5.47 Mn |
| Dec 31, 2023 | -5.66 Mn |
| Sep 30, 2023 | -9.64 Mn |
| Jun 30, 2023 | -21.16 Mn |
| Mar 31, 2023 | -31.52 Mn |
| Dec 31, 2022 | -22.83 Mn |
| Sep 30, 2022 | -21.54 Mn |
| Jun 30, 2022 | -3.97 Mn |
| Mar 31, 2022 | -24.52 Mn |
| Dec 31, 2021 | -15.17 Mn |
| Sep 30, 2021 | -11.81 Mn |
API Access
Castle Biosciences Operating Income API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-income&ticker=CSTL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-income", "ticker": "CSTL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-income&ticker=CSTL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();