Growth Metrics

Calidi Biotherapeutics (CLDI) Return on Equity (2022 - 2025)

Calidi Biotherapeutics' quarterly Return on Equity came in at 0.04% in Q4 2025, down 9.0% year-on-year from 0.04% in Q4 2024, and up 15.73% quarter-over-quarter from 0.04% in Q3 2025.

Calidi Biotherapeutics has reported Return on Equity for 4 years, with the latest figure at 0.04% in Q4 2025.

  • For the quarter ending Q4 2025, Return on Equity fell 9.0% year-over-year to 0.04%; the trailing twelve-month figure through Dec 2025 stood at 0.04% (down 9.0% YoY), and the FY2025 full-year result was 0.07%, down 14.0% from the prior year.
  • Return on Equity for Q4 2025 stood at 0.04%, up from 0.04% in the prior quarter.
  • The five-year high for Return on Equity was 0.06% in Q4 2023, with the low at 0.04% in Q3 2025.
  • Average Return on Equity over 4 years is 0.0%, with a median of 0.0% recorded in 2023.
  • Year-over-year, Return on Equity advanced 6 bps in 2023 and retreated 9 bps in 2025.
  • Tracing CLDI's Return on Equity over 4 years: stood at 0.0% in 2022, then jumped by 3840 bps to 0.06% in 2023, then slipped by 9 bps to 0.06% in 2024, then tumbled by 165 bps to 0.04% in 2025.
  • The last three Return on Equity figures came in at 0.04% (Q4 2025), 0.04% (Q3 2025), and 0.04% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - -0.04%
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - -
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn -
4 Nanobiotix 2,282.79 Bn 2,282.72 Bn - -
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - -0.01%
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 0.00%
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn 0.00%
8 Evaxion A 65.44 Bn 65.42 Bn - -
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 0.01%
10 Calidi Biotherapeutics - - - -0.04%

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -0.04%
Sep 30, 2025 -0.04%
Jun 30, 2025 -0.04%
Mar 31, 2025 -0.04%
Dec 31, 2024 0.06%
Sep 30, 2024 0.02%
Jun 30, 2024 0.02%
Mar 31, 2024 0.03%
Dec 31, 2023 0.06%
Sep 30, 2023 0.01%
Jun 30, 2023 0.01%
Mar 31, 2023 0.00%
Dec 31, 2022 0.00%
Sep 30, 2022 0.00%