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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Vertex Pharmaceuticals (VRTX) Return on Equity (2016 - 2025)

Vertex Pharmaceuticals has reported Return on Equity over the past 16 years, most recently at 0.22% for Q4 2025.

  • Quarterly results put Return on Equity at 0.22% for Q4 2025, up 25.0% from a year ago — trailing twelve months through Dec 2025 was 0.22% (up 25.0% YoY), and the annual figure for FY2025 was 0.23%, up 26.0%.
  • Return on Equity for Q4 2025 was 0.22% at Vertex Pharmaceuticals, up from 0.21% in the prior quarter.
  • Over the last five years, Return on Equity for VRTX hit a ceiling of 0.31% in Q1 2021 and a floor of 0.06% in Q1 2025.
  • Median Return on Equity over the past 5 years was 0.22% (2024), compared with a mean of 0.18%.
  • Peak annual rise in Return on Equity hit 25bps in 2025, while the deepest fall reached -28bps in 2025.
  • Vertex Pharmaceuticals' Return on Equity stood at 0.24% in 2021, then rose by 3bps to 0.25% in 2022, then fell by -14bps to 0.21% in 2023, then plummeted by -116bps to 0.03% in 2024, then skyrocketed by 757bps to 0.22% in 2025.
  • The last three reported values for Return on Equity were 0.22% (Q4 2025), 0.21% (Q3 2025), and 0.22% (Q2 2025) per Business Quant data.