Growth Metrics

Calidi Biotherapeutics (CLDI) Invested Capital (2021 - 2025)

Calidi Biotherapeutics' quarterly Invested Capital came in at $3.8 million in Q4 2025, up 71.57% year-on-year from $2.2 million in Q4 2024, and down 47.78% quarter-over-quarter from $7.2 million in Q3 2025.

Calidi Biotherapeutics has reported Invested Capital for 5 years, with the latest figure at $3.8 million in Q4 2025.

  • For the quarter ending Q4 2025, Invested Capital rose 71.57% year-over-year to $3.8 million; the trailing twelve-month figure through Dec 2025 stood at $3.8 million (up 71.57% YoY), and the FY2025 full-year result was $3.8 million, up 71.57% from the prior year.
  • Invested Capital for Q4 2025 stood at $3.8 million, down from $7.2 million in the prior quarter.
  • The five-year high for Invested Capital was $7.3 million in Q1 2025, with the low at -$63.4 million in Q2 2023.
  • Average Invested Capital over 5 years is -$20.1 million, with a median of -$11.5 million recorded in 2024.
  • Year-over-year, Invested Capital tumbled 10092.55% in 2024 and jumped 175.13% in 2025.
  • Tracing CLDI's Invested Capital over 5 years: stood at -$31.6 million in 2021, then plunged by 56.4% to -$49.4 million in 2022, then soared by 83.34% to -$8.2 million in 2023, then surged by 126.61% to $2.2 million in 2024, then jumped by 71.57% to $3.8 million in 2025.
  • The last three Invested Capital figures came in at $3.8 million (Q4 2025), $7.2 million (Q3 2025), and $2.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - 595,226.00
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - -
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn -
4 Nanobiotix 2,282.79 Bn 2,282.72 Bn - 110.96 Mn
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - 14.38 Mn
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 19.36 Bn
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn 31.42 Bn
8 Evaxion A 65.44 Bn 65.42 Bn - -
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 1.08 Bn
10 Calidi Biotherapeutics - - - 3.76 Mn

Historic Data

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DateValue
Dec 31, 2025 3.76 Mn
Sep 30, 2025 7.20 Mn
Jun 30, 2025 2.08 Mn
Mar 31, 2025 7.30 Mn
Dec 31, 2024 2.19 Mn
Sep 30, 2024 -9.58 Mn
Jun 30, 2024 -11.54 Mn
Mar 31, 2024 -14.37 Mn
Dec 31, 2023 -8.24 Mn
Sep 30, 2023 -94,000.00
Jun 30, 2023 -63.44 Mn
Mar 31, 2023 -54.96 Mn
Dec 31, 2022 -49.44 Mn
Sep 30, 2022 -43.93 Mn
Jun 30, 2022 -39.64 Mn
Mar 31, 2022 -37.62 Mn
Dec 31, 2021 -31.61 Mn