Growth Metrics

Calidi Biotherapeutics (CLDI) EBT (2022 - 2025)

Calidi Biotherapeutics' quarterly EBT came in at -$4.1 million in Q4 2025, up 2.03% year-on-year from -$4.0 million in Q4 2024, and up 21.47% quarter-over-quarter from -$5.2 million in Q3 2025.

Calidi Biotherapeutics has reported EBT for 4 years, with the latest figure at -$4.1 million in Q4 2025.

  • For the quarter ending Q4 2025, EBT rose 2.03% year-over-year to -$4.1 million; the trailing twelve-month figure through Dec 2025 stood at -$20.0 million (up 9.67% YoY), and the FY2025 full-year result was -$20.0 million, up 9.67% from the prior year.
  • EBT for Q4 2025 stood at -$4.1 million, up from -$5.2 million in the prior quarter.
  • The five-year high for EBT was $4.2 million in Q2 2022, with the low at -$12.5 million in Q2 2023.
  • Average EBT over 4 years is -$4.9 million, with a median of -$5.3 million recorded in 2022.
  • Peak annual rise in EBT reached 62.4% in 2023, while the deepest fall reached 541.67% in 2023.
  • Tracing CLDI's EBT over 4 years: stood at -$7.8 million in 2022, then declined by 6.1% to -$8.2 million in 2023, then surged by 49.65% to -$4.1 million in 2024, then increased by 2.03% to -$4.1 million in 2025.
  • The last three EBT figures came in at -$4.1 million (Q4 2025), -$5.2 million (Q3 2025), and -$5.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - -2.99 Mn
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - -
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,282.79 Bn 2,282.72 Bn - -
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - -15.31 Mn
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 1.25 Bn
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn 831.20 Mn
8 Evaxion A 65.44 Bn 65.42 Bn - -3.18 Mn
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 221.65 Mn
10 Calidi Biotherapeutics - - - -4.06 Mn

Historic Data

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DateValue
Dec 31, 2025 -4.06 Mn
Sep 30, 2025 -5.17 Mn
Jun 30, 2025 -5.76 Mn
Mar 31, 2025 -5.06 Mn
Dec 31, 2024 -4.15 Mn
Sep 30, 2024 -5.07 Mn
Jun 30, 2024 -5.76 Mn
Mar 31, 2024 -7.22 Mn
Dec 31, 2023 -8.23 Mn
Sep 30, 2023 -2.01 Mn
Jun 30, 2023 -12.50 Mn
Mar 31, 2023 -6.46 Mn
Dec 31, 2022 -7.76 Mn
Sep 30, 2022 -5.35 Mn
Jun 30, 2022 4.16 Mn
Mar 31, 2022 1.46 Mn