Growth Metrics

Calidi Biotherapeutics (CLDI) Profit After Tax (2022 - 2025)

Calidi Biotherapeutics' quarterly Profit After Tax came in at -$4.2 million in Q4 2025, down 3.21% year-on-year from -$4.4 million in Q4 2024, and up 18.18% quarter-over-quarter from -$5.1 million in Q3 2025.

Calidi Biotherapeutics has reported Profit After Tax for 4 years, with the latest figure at -$4.2 million in Q4 2025.

  • For the quarter ending Q4 2025, Profit After Tax fell 3.21% year-over-year to -$4.2 million; the trailing twelve-month figure through Dec 2025 stood at -$20.2 million (up 8.78% YoY), and the FY2025 full-year result was -$20.1 million, up 9.39% from the prior year.
  • Profit After Tax for Q4 2025 stood at -$4.2 million, up from -$5.1 million in the prior quarter.
  • The five-year high for Profit After Tax was -$2.0 million in Q3 2023, with the low at -$12.5 million in Q2 2023.
  • Average Profit After Tax over 4 years is -$6.1 million, with a median of -$5.6 million recorded in 2022.
  • Peak annual rise in Profit After Tax reached 62.2% in 2023, while the deepest fall reached 173.19% in 2023.
  • Tracing CLDI's Profit After Tax over 4 years: stood at -$7.8 million in 2022, then decreased by 6.1% to -$8.2 million in 2023, then soared by 50.39% to -$4.1 million in 2024, then slipped by 3.21% to -$4.2 million in 2025.
  • The last three Profit After Tax figures came in at -$4.2 million (Q4 2025), -$5.1 million (Q3 2025), and -$5.8 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - -2.99 Mn
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - -
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn 30.90 Mn
4 Nanobiotix 2,282.79 Bn 2,282.72 Bn - -
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - -14.46 Mn
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 1.03 Bn
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn 727.20 Mn
8 Evaxion A 65.44 Bn 65.42 Bn - -3.63 Mn
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 205.99 Mn
10 Calidi Biotherapeutics - - - -4.21 Mn

Historic Data

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DateValue
Dec 31, 2025 -4.21 Mn
Sep 30, 2025 -5.15 Mn
Jun 30, 2025 -5.76 Mn
Mar 31, 2025 -5.06 Mn
Dec 31, 2024 -4.08 Mn
Sep 30, 2024 -5.05 Mn
Jun 30, 2024 -5.77 Mn
Mar 31, 2024 -7.23 Mn
Dec 31, 2023 -8.23 Mn
Sep 30, 2023 -2.02 Mn
Jun 30, 2023 -12.50 Mn
Mar 31, 2023 -6.46 Mn
Dec 31, 2022 -7.76 Mn
Sep 30, 2022 -5.36 Mn
Jun 30, 2022 -4.58 Mn
Mar 31, 2022 -7.74 Mn