Growth Metrics

Calidi Biotherapeutics (CLDI) Net Cash Flow (2022 - 2025)

Calidi Biotherapeutics' quarterly Net Cash Flow came in at -$4.8 million in Q4 2025, down 162.93% year-on-year from $7.7 million in Q4 2024, and down 191.99% quarter-over-quarter from $5.3 million in Q3 2025.

Calidi Biotherapeutics has reported Net Cash Flow for 4 years, with the latest figure at -$4.8 million in Q4 2025.

  • For the quarter ending Q4 2025, Net Cash Flow fell 162.93% year-over-year to -$4.8 million; the trailing twelve-month figure through Dec 2025 stood at -$4.0 million (down 152.31% YoY), and the FY2025 full-year result was -$4.0 million, down 152.31% from the prior year.
  • Net Cash Flow for Q4 2025 stood at -$4.8 million, down from $5.3 million in the prior quarter.
  • The five-year high for Net Cash Flow was $8.1 million in Q3 2023, with the low at -$8.2 million in Q4 2023.
  • Average Net Cash Flow over 4 years is $225812.5, with a median of $6660.5 recorded in 2022.
  • Peak annual rise in Net Cash Flow reached 789.02% in 2023, while the deepest fall reached 3000.35% in 2023.
  • Tracing CLDI's Net Cash Flow over 4 years: stood at $282000.0 in 2022, then tumbled by 3000.35% to -$8.2 million in 2023, then surged by 193.87% to $7.7 million in 2024, then plunged by 162.93% to -$4.8 million in 2025.
  • The last three Net Cash Flow figures came in at -$4.8 million (Q4 2025), $5.3 million (Q3 2025), and -$5.4 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 1,638,563.89 Bn 1,638,563.89 Bn - 2.44 Mn
2 Alterity Therapeutics 767,934.24 Bn 767,934.20 Bn - -
3 Legend Biotech 2,937.00 Bn 2,936.10 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,282.79 Bn 2,282.72 Bn - -
5 Akari Therapeutics 2,169.69 Bn 2,169.69 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 110.41 Bn 103.16 Bn 2.59 Bn 457.40 Mn
7 Regeneron Pharmaceuticals 66.44 Bn 57.69 Bn 3.31 Bn -152.20 Mn
8 Evaxion A 65.44 Bn 65.42 Bn - -
9 Alnylam Pharmaceuticals 39.53 Bn 36.52 Bn 959.66 Mn 60.68 Mn
10 Calidi Biotherapeutics - - - -4.83 Mn

Historic Data

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DateValue
Dec 31, 2025 -4.83 Mn
Dec 31, 2025 -4.83 Mn
Sep 30, 2025 5.25 Mn
Sep 30, 2025 5.25 Mn
Jun 30, 2025 -5.43 Mn
Jun 30, 2025 -5.43 Mn
Mar 31, 2025 1.00 Mn
Mar 31, 2025 1.00 Mn
Dec 31, 2024 7.68 Mn
Dec 31, 2024 7.68 Mn
Sep 30, 2024 1.09 Mn
Sep 30, 2024 1.09 Mn
Jun 30, 2024 -294,000.00
Jun 30, 2024 -294,000.00
Mar 31, 2024 -823,000.00
Mar 31, 2024 -823,000.00
Dec 31, 2023 -8.18 Mn
Dec 31, 2023 -8.18 Mn
Sep 30, 2023 8.06 Mn
Sep 30, 2023 8.06 Mn
Jun 30, 2023 1.16 Mn
Jun 30, 2023 1.16 Mn
Mar 31, 2023 547,000.00
Mar 31, 2023 547,000.00
Dec 31, 2022 282,000.00
Dec 31, 2022 282,000.00
Sep 30, 2022 -1.17 Mn
Sep 30, 2022 -1.17 Mn
Jun 30, 2022 -268,679.00
Jun 30, 2022 -268,679.00
Mar 31, 2022 -465,131.00
Mar 31, 2022 -465,131.00