Calidi Biotherapeutics (CLDI) Research & Development (2022 - 2025)
Calidi Biotherapeutics' quarterly Research & Development came in at $2.4 million in Q4 2025, up 29.92% year-on-year from $1.8 million in Q4 2024, and little changed quarter-over-quarter from $2.4 million in Q3 2025.
Calidi Biotherapeutics has reported Research & Development for 4 years, with the latest figure at $2.4 million in Q4 2025.
- For the quarter ending Q4 2025, Research & Development rose 29.92% year-over-year to $2.4 million; the trailing twelve-month figure through Dec 2025 stood at $9.7 million (up 9.68% YoY), and the FY2025 full-year result was $9.7 million, up 9.68% from the prior year.
- Research & Development for Q4 2025 stood at $2.4 million, roughly flat from $2.4 million in the prior quarter.
- The five-year high for Research & Development was $4.0 million in Q4 2023, with the low at $1.8 million in Q4 2024.
- Average Research & Development over 4 years is $2.6 million, with a median of $2.4 million recorded in 2025.
- Year-over-year, Research & Development soared 74.9% in 2023 and slumped 54.14% in 2024.
- Tracing CLDI's Research & Development over 4 years: stood at $2.3 million in 2022, then soared by 74.9% to $4.0 million in 2023, then tumbled by 54.14% to $1.8 million in 2024, then advanced by 29.92% to $2.4 million in 2025.
- The last three Research & Development figures came in at $2.4 million (Q4 2025), $2.4 million (Q3 2025), and $2.6 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,638,563.89 Bn | 1,638,563.89 Bn | - | 626,092.00 |
| 2 | Alterity Therapeutics | 767,934.24 Bn | 767,934.20 Bn | - | 4.32 Mn |
| 3 | Legend Biotech | 2,937.00 Bn | 2,936.10 Bn | 242.10 Mn | -101.30 Mn |
| 4 | Nanobiotix | 2,282.79 Bn | 2,282.72 Bn | - | - |
| 5 | Akari Therapeutics | 2,169.69 Bn | 2,169.69 Bn | - | 1.46 Mn |
| 6 | Vertex Pharmaceuticals | 110.41 Bn | 103.16 Bn | 2.59 Bn | 961.60 Mn |
| 7 | Regeneron Pharmaceuticals | 66.44 Bn | 57.69 Bn | 3.31 Bn | 1.54 Bn |
| 8 | Evaxion A | 65.44 Bn | 65.42 Bn | - | -2.30 Mn |
| 9 | Alnylam Pharmaceuticals | 39.53 Bn | 36.52 Bn | 959.66 Mn | 364.87 Mn |
| 10 | Calidi Biotherapeutics | - | - | - | 2.36 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 2.36 Mn |
| Sep 30, 2025 | 2.36 Mn |
| Jun 30, 2025 | 2.59 Mn |
| Mar 31, 2025 | 2.43 Mn |
| Dec 31, 2024 | 1.82 Mn |
| Sep 30, 2024 | 2.15 Mn |
| Jun 30, 2024 | 2.17 Mn |
| Mar 31, 2024 | 2.74 Mn |
| Dec 31, 2023 | 3.96 Mn |
| Sep 30, 2023 | 3.25 Mn |
| Jun 30, 2023 | 3.18 Mn |
| Mar 31, 2023 | 2.62 Mn |
| Dec 31, 2022 | 2.26 Mn |
| Sep 30, 2022 | 1.95 Mn |