Calidi Biotherapeutics (CLDI) Operating Expenses (2022 - 2025)
Calidi Biotherapeutics' quarterly Operating Expenses came in at $4.5 million in Q4 2025, up 10.93% year-on-year from $4.0 million in Q4 2024, and down 11.53% quarter-over-quarter from $5.0 million in Q3 2025.
Calidi Biotherapeutics has reported Operating Expenses for 4 years, with the latest figure at $4.5 million in Q4 2025.
- For the quarter ending Q4 2025, Operating Expenses rose 10.93% year-over-year to $4.5 million; the trailing twelve-month figure through Dec 2025 stood at $20.2 million (down 7.05% YoY), and the FY2025 full-year result was $20.2 million, down 7.05% from the prior year.
- Operating Expenses for Q4 2025 stood at $4.5 million, down from $5.0 million in the prior quarter.
- The five-year high for Operating Expenses was $9.8 million in Q4 2023, with the low at $361622.0 in Q2 2022.
- Average Operating Expenses over 4 years is $5.2 million, with a median of $5.3 million recorded in 2023.
- Year-over-year, Operating Expenses jumped 1707.69% in 2023 and plunged 59.0% in 2024.
- Tracing CLDI's Operating Expenses over 4 years: stood at $4.7 million in 2022, then jumped by 109.47% to $9.8 million in 2023, then sank by 59.0% to $4.0 million in 2024, then advanced by 10.93% to $4.5 million in 2025.
- The last three Operating Expenses figures came in at $4.5 million (Q4 2025), $5.0 million (Q3 2025), and $5.7 million (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,638,563.89 Bn | 1,638,563.89 Bn | - | 2.97 Mn |
| 2 | Alterity Therapeutics | 767,934.24 Bn | 767,934.20 Bn | - | 4.33 Mn |
| 3 | Legend Biotech | 2,937.00 Bn | 2,936.10 Bn | 242.10 Mn | -138.30 Mn |
| 4 | Nanobiotix | 2,282.79 Bn | 2,282.72 Bn | - | - |
| 5 | Akari Therapeutics | 2,169.69 Bn | 2,169.69 Bn | - | 15.76 Mn |
| 6 | Vertex Pharmaceuticals | 110.41 Bn | 103.16 Bn | 2.59 Bn | 1.85 Bn |
| 7 | Regeneron Pharmaceuticals | 66.44 Bn | 57.69 Bn | 3.31 Bn | 2.96 Bn |
| 8 | Evaxion A | 65.44 Bn | 65.42 Bn | - | -3.82 Mn |
| 9 | Alnylam Pharmaceuticals | 39.53 Bn | 36.52 Bn | 959.66 Mn | 898.54 Mn |
| 10 | Calidi Biotherapeutics | - | - | - | 4.47 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 4.47 Mn |
| Sep 30, 2025 | 5.05 Mn |
| Jun 30, 2025 | 5.66 Mn |
| Mar 31, 2025 | 5.06 Mn |
| Dec 31, 2024 | 4.03 Mn |
| Sep 30, 2024 | 5.23 Mn |
| Jun 30, 2024 | 5.77 Mn |
| Mar 31, 2024 | 6.75 Mn |
| Dec 31, 2023 | 9.82 Mn |
| Sep 30, 2023 | 7.22 Mn |
| Jun 30, 2023 | 6.54 Mn |
| Mar 31, 2023 | 5.41 Mn |
| Dec 31, 2022 | 4.69 Mn |
| Sep 30, 2022 | 6.99 Mn |
| Jun 30, 2022 | 361,622.00 |
| Mar 31, 2022 | 528,858.00 |