Calidi Biotherapeutics CLDI
NYSE CLDI
$1.34 +0.00 (+0.00%)
As of: Aug 21, 2026 · 3:59 PM EDT

Calidi Biotherapeutics (CLDI) Free Cash Flow (2022 - 2025)

Calidi Biotherapeutics (CLDI) posted quarterly Free Cash Flow of -$5.1 million for Q4 2025, up 6.41% year-over-year from -$4.8 million in Q4 2024, and down 19.11% quarter-over-quarter from -$4.3 million in Q3 2025.

Calidi Biotherapeutics (CLDI) Free Cash Flow (2022 - 2025) Analysis & Trends

Calidi Biotherapeutics' Free Cash Flow history runs 4 years deep, the most recent figure standing at -$5.1 million for Q4 2025.

  • In Q4 2025, Free Cash Flow rose 6.41% year-over-year to -$5.1 million; the TTM figure through Dec 2025 stood at -$21.4 million (down 8.68% YoY), while the FY2025 annual figure was -$21.4 million, down 8.68% from the prior year.
  • Free Cash Flow for Q4 2025 stood at -$5.1 million, down from -$4.3 million in the prior quarter.
  • The five-year high for Free Cash Flow was -$268679.0 in Q2 2022, with the low at -$14.0 million in Q3 2023.
  • The 4-year median for Free Cash Flow is -$5.0 million (2023), against an average of -$5.1 million.
  • The sharpest annual moves came in 2023 and 2024: Free Cash Flow sank 1742.35% in 2023, then surged 64.64% in 2024.
  • Calidi Biotherapeutics' Free Cash Flow stood at -$4.0 million in 2022, then tumbled by 30.2% to -$5.3 million in 2023, then decreased by 3.27% to -$5.4 million in 2024, then gained by 6.41% to -$5.1 million in 2025.
  • Business Quant data shows CLDI's Free Cash Flow at -$5.1 million in Q4 2025, -$4.3 million in Q3 2025, and -$4.9 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -563.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 437.80 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 292.04 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 433.84 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -95.09 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 477.44 Mn
10 Calidi Biotherapeutics 1.88 Mn -2.22 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 -5.08 Mn
Dec 31, 2025 -5.08 Mn
Sep 30, 2025 -4.27 Mn
Sep 30, 2025 -4.27 Mn
Jun 30, 2025 -4.94 Mn
Jun 30, 2025 -4.94 Mn
Mar 31, 2025 -7.14 Mn
Mar 31, 2025 -7.14 Mn
Dec 31, 2024 -5.43 Mn
Dec 31, 2024 -5.43 Mn
Sep 30, 2024 -4.95 Mn
Sep 30, 2024 -4.95 Mn
Jun 30, 2024 -5.49 Mn
Jun 30, 2024 -5.49 Mn
Mar 31, 2024 -3.84 Mn
Mar 31, 2024 -3.84 Mn
Dec 31, 2023 -5.26 Mn
Dec 31, 2023 -5.26 Mn
Sep 30, 2023 -14.01 Mn
Sep 30, 2023 -14.01 Mn