Growth Metrics

Soleno Therapeutics (SLNO) Return on Capital Employed (2014 - 2026)

Soleno Therapeutics (SLNO) reported Return on Capital Employed of 16.37% for Q1 2026, up 8435.0% year-over-year from 0.19% in Q1 2025, and up 805.01% on a QoQ basis from 1.81% in Q4 2025.

Soleno Therapeutics (SLNO) has 13 years of Return on Capital Employed data on file, last reported at 16.37% in Q1 2026.

  • Quarterly Return on Capital Employed rose 8435.0% year-over-year to 16.37% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 16.37% (up 8435.0% YoY) and the FY2025 annual result came in at 2.44%, up 8160.0% from the prior year.
  • Return on Capital Employed improved to 16.37% in Q1 2026 per SLNO's latest filing, from 1.81% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 16.37% in Q1 2026 and bottomed at 181.25% in Q3 2023.
  • The 5-year median for Return on Capital Employed is 63.6% (2024), against an average of 72.94%.
  • The widest annual swing landed in 2023, when Return on Capital Employed sank 10255 bps; it then jumped 14405 bps in 2024.
  • Tracing SLNO's Return on Capital Employed over 5 years: stood at 111.27% in 2022, then soared by 66 bps to 37.41% in 2023, then slumped by 70 bps to 63.6% in 2024, then jumped by 103 bps to 1.81% in 2025, then surged by 805 bps to 16.37% in 2026.
  • Per Business Quant, the three latest SLNO Return on Capital Employed figures stand at 16.37% (Q1 2026), 1.81% (Q4 2025), and 20.63% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - 450.31%
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -107.40%
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 21.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 20.34%
10 Soleno Therapeutics 2.76 Bn 2.51 Bn 93.41 Mn 16.37%

Historic Data

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DateValue
Mar 31, 2026 16.37%
Dec 31, 2025 1.81%
Sep 30, 2025 -20.63%
Jun 30, 2025 -62.97%
Mar 31, 2025 -67.99%
Dec 31, 2024 -63.60%
Sep 30, 2024 -49.91%
Jun 30, 2024 -31.95%
Mar 31, 2024 -34.96%
Dec 31, 2023 -37.41%
Sep 30, 2023 -181.25%
Jun 30, 2023 -176.00%
Mar 31, 2023 -177.60%
Dec 31, 2022 -111.27%
Sep 30, 2022 -80.46%
Jun 30, 2022 -73.45%
Mar 31, 2022 -88.68%
Dec 31, 2021 -101.53%
Sep 30, 2021 -99.60%
Jun 30, 2021 -81.24%
Mar 31, 2021 -70.45%
Dec 31, 2020 -60.72%
Sep 30, 2020 -52.11%
Jun 30, 2020 -70.79%
Mar 31, 2020 -99.76%
Dec 31, 2019 -82.45%
Sep 30, 2019 -72.45%
Jun 30, 2019 -53.54%
Mar 31, 2019 -40.78%
Dec 31, 2018 -40.73%
Sep 30, 2018 -53.97%
Jun 30, 2018 -44.75%
Mar 31, 2018 -39.94%
Dec 31, 2017 -39.30%
Sep 30, 2017 -33.04%
Jun 30, 2017 -27.14%
Mar 31, 2017 -42.58%
Dec 31, 2016 -198.09%
Sep 30, 2016 -233.87%
Jun 30, 2016 -238.20%
Mar 31, 2016 -225.15%
Dec 31, 2015 -267.14%
Sep 30, 2015 -524.67%
Jun 30, 2015 219.79%
Mar 31, 2015 -84.45%
Dec 31, 2014 -137.37%