Soleno Therapeutics (SLNO) Operating Expenses (2013 - 2026)

Soleno Therapeutics (SLNO) posted quarterly Operating Expenses of $63.3 million for Q1 2026, up 38.44% year-over-year from $45.7 million in Q1 2025, and up 21.42% quarter-over-quarter from $52.2 million in Q4 2025.

Soleno Therapeutics (SLNO) Operating Expenses (2013 - 2026) Analysis & Trends

Soleno Therapeutics (SLNO) has reported Operating Expenses for 14 consecutive years, with $63.3 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Operating Expenses rose 38.44% year-over-year to $63.3 million; the TTM figure through Mar 2026 stood at $198.6 million (down 5.41% YoY), while the FY2025 annual figure was $181.0 million, down 3.56% from the prior year.
  • Operating Expenses climbed to $63.3 million in Q1 2026 per SLNO's latest filing, from $52.2 million in the prior quarter.
  • Across five years, Operating Expenses topped out at $80.2 million in Q3 2024 and bottomed at $5.6 million in Q4 2022.
  • Historically, Operating Expenses has averaged $29.3 million across 5 years, with a median of $23.5 million in 2024.
  • Annual changes were most pronounced in 2024 — Operating Expenses soared 672.61% — and 2025, when it tumbled 45.25%.
  • Soleno Therapeutics' Operating Expenses stood at $5.6 million in 2022, then soared by 147.95% to $13.9 million in 2023, then jumped by 324.99% to $59.1 million in 2024, then declined by 11.78% to $52.2 million in 2025, then rose by 21.42% to $63.3 million in 2026.
  • Business Quant data shows SLNO's Operating Expenses at $63.3 million in Q1 2026, $52.2 million in Q4 2025, and $43.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 2.09 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 3.00 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 2.89 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - 505.13 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 1.21 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 4,978.15
7 Royalty Pharma 33.72 Bn 35.84 Bn - 541.02 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.06 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 427.03 Mn
10 Soleno Therapeutics 2.74 Bn 2.49 Bn 93.41 Mn 63.33 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 63.33 Mn
Dec 31, 2025 52.15 Mn
Sep 30, 2025 43.91 Mn
Jun 30, 2025 39.18 Mn
Mar 31, 2025 45.74 Mn
Dec 31, 2024 59.12 Mn
Sep 30, 2024 80.21 Mn
Jun 30, 2024 24.87 Mn
Mar 31, 2024 23.48 Mn
Dec 31, 2023 13.91 Mn
Sep 30, 2023 10.38 Mn
Jun 30, 2023 8.62 Mn
Mar 31, 2023 8.47 Mn
Dec 31, 2022 5.61 Mn
Sep 30, 2022 6.24 Mn
Jun 30, 2022 6.78 Mn
Mar 31, 2022 5.77 Mn
Dec 31, 2021 3.00 Mn
Sep 30, 2021 8.29 Mn
Jun 30, 2021 11.09 Mn