Soleno Therapeutics Inc (SLNO) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

54,921,916Shares Outstanding

65,548,476Shares held by institutions

$3,464,236,957Value of institutional holdings

119.35%Institutional ownership %

18.08%Shares Changed QoQ

244No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Soleno Therapeutics Inc (NASDAQ:SLNO) is held by 244 institutional investors per 13F filings through December 2025.

Collectively, these holders controlled 112.2% of Soleno Therapeutics's outstanding shares in December 2025, down from 121.4% in September 2025.
They increased total shares held in Soleno Therapeutics by 11.42% from last quarter, and the number of investors in SLNO increased 49.69% annually.
Of these 244 holders, 163 added to their stakes in Soleno Therapeutics, 64 trimmed positions, and 17 made no changes.
Altogether, these fund groups held 61.61Mn shares in SLNO by December 2025, up by 6.32Mn shares quarter on quarter, and up 10.01Mn shares year over year.
As of December 31, 2025, Pictet Asset Management Holding SA held the largest stake in Soleno Therapeutics with 616.22K shares, accounting for 1.12% of total shares outstanding.
The biggest buyers of Soleno Therapeutics for the quarter ending December 2025 included E Fund Management Co., Ltd. (10.01K), MOODY ALDRICH PARTNERS LLC (1.96K), SIGNATUREFD, LLC (120), Private Wealth Management Group, LLC (54), Stone House Investment Management, LLC (50).
The biggest sellers of Soleno Therapeutics for the quarter ending December 2025 included SG Americas Securities, LLC (21.06K), Pictet Asset Management Holding SA (7.91K), BANQUE PICTET & CIE SA (5.07K), OPPENHEIMER & CO INC (86), Versant Capital Management, Inc (76).
Soleno Therapeutics's 10 largest shareholders as of December 2025 include Pictet Asset Management Holding SA (616.22K), MOODY ALDRICH PARTNERS LLC (48.26K), BANQUE PICTET & CIE SA (38.73K), SG Americas Securities, LLC (19.14K), E Fund Management Co., Ltd. (10.01K), OPPENHEIMER & CO INC (8.66K), FNY Investment Advisers, LLC (3.5K), Sterling Capital Management LLC (327), Farther Finance Advisors, LLC (164), SIGNATUREFD, LLC (131) per Business Quant data.

244 Institutional Holders

65,548,476 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
FMR LLC	31 Dec, 2025	8,079,304	79,622	1.00%	$374,071,758.00
Janus Henderson Group Plc	31 Dec, 2025	7,178,354	1,122,015	18.53%	$332,302,144.00
Avoro Capital Advisors LLC	31 Dec, 2025	5,800,000	3,222,223	125.00%	$268,540,000.00
BlackRock, Inc.	31 Dec, 2025	3,871,639	379,387	10.86%	$179,256,886.00
WELLINGTON MANAGEMENT GROUP LLP	31 Dec, 2025	3,322,799	1,010,704	43.71%	$153,845,595.00
VANGUARD GROUP INC	31 Dec, 2025	3,060,361	253,212	9.02%	$141,694,714.00
State Street Corp	31 Dec, 2025	2,649,626	476,590	21.93%	$122,677,684.00
Goldman Sachs Group Inc	31 Dec, 2025	1,826,100	1,270,662	228.77%	$84,548,430.00
Nantahala Capital Management, LLC	31 Dec, 2025	1,314,002	450,239	52.13%	$60,838,293.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	1,236,321	256,495	26.18%	$57,241,662.00
Commodore Capital LP	31 Dec, 2025	1,200,000	-150,000	-11.11%	$55,560,000.00
BRAIDWELL LP	31 Dec, 2025	1,187,859	-94,130	-7.34%	$54,997,872.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,163,338	78,386	7.22%	$53,870,660.00
Polar Capital Holdings Plc	31 Dec, 2025	1,136,929	-54,194	-4.55%	$52,639,813.00
Woodline Partners LP	31 Dec, 2025	1,111,778	840,946	310.50%	$51,475,321.00
Deep Track Capital, LP	31 Dec, 2025	1,000,000	1,000,000	0.00%	$46,300,000.00
Vivo Capital, LLC	31 Dec, 2025	894,909	-1,383,294	-60.72%	$41,434,287.00
Invesco Ltd.	31 Dec, 2025	875,019	-625,506	-41.69%	$40,513,380.00
READYSTATE ASSET MANAGEMENT LP	31 Dec, 2025	874,447	668,640	324.89%	$40,486,896.00
Franklin Resources Inc	31 Dec, 2025	823,958	-11,793	-1.41%	$38,149,268.00

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